Generic Name and Formulations:
Acetaminophen 325mg, chlorpheniramine maleate 2mg, dextromethorphan HBr 10mg, phenylephrine HCl 5mg; per Cool Burst caplet.
McNeil Consumer Healthcare
Congestion, rhinorrhea, cough, sore throat, headache, fever, minor aches and pains.
Swallow whole. 2 caplets every 4 hours; max 12 caplets/24 hours.
During or within 14 days of MAOIs. Concomitant other acetaminophen products.
Hepatic dysfunction. Cardiovascular disease. Hypertension. GI or GU obstruction. Thyroid disease. Glaucoma. Diabetes. Asthma. Lower respiratory disorders. Pregnancy. Nursing mothers.
Analgesic + antihistamine + antitussive + sympathomimetic.
See Contraindications. Hypertensive crisis with MAOIs. Increased risk of hepatotoxicity with ≥3 alcoholic drinks/day; avoid. β-blockers may increase pressor effects of sympathomimetics. Antihypertensives antagonized. Increased CNS effects with other CNS depressants.
Drowsiness, anticholinergic effects, nervousness, dizziness, insomnia, excitability in children, hepatotoxicity (overdosage).
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