This activity is provided by Paradigm Medical Communications, LLC.
This activity is supported by an educational grant from Genentech, Inc.
In this era of personalized medicine in which the identification of targetable genetic alterations will help determine appropriate treatment in patients with non-small cell lung cancer (NSCLC), oncology clinicians, along with pathologists, require new insights into specific techniques that are being used to identify the targets and then to select the specific treatment(s) that correspond to these targets. This interactive infographic will guide clinicians through the process of identifying predictive biomarkers and matching them up with new and emerging targeted therapies. They will also be able to evaluate clinical trial data for new and emerging targeted treatments in NSCLC with genetic mutations, as well as review recommendations on initial and repeat biomarker testing.
Recommendations for Genetic Testing
Genetic Markers Associated With NSCLC
Targeted Therapies for Genetic Alterations
Newer Therapies: Current and Ongoing Late-Phase Trial Data
Resources on NSCLC
This activity has been designed to address the educational needs of medical oncologists and pathologists. It will also be of benefit to interventional radiologists, pulmonologists, surgical oncologists, thoracic surgeons, and other healthcare providers involved in the management of non-small cell lung cancer, including oncology nurses, nurse practitioners, and PAs.
Upon proper completion of this activity, participants should be better able to:
Identify the types of genetic mutations found in non-small cell lung cancer and associated guideline recommendations for treatment
Evaluate clinical trial data for new and emerging targeted treatments in non-small cell lung cancer with genetic mutations
Summarize the recommendations regarding initial and repeat biomarker testing for genetic mutations in non-small cell lung cancer
Conflict of Interest Disclosure Policy
Paradigm Medical Communications, LLC has implemented a system to resolve conflicts of interest for each CME activity to help ensure content is objective, fair and balanced, independent, and aligned with the public interest. Conflicts, if any, are resolved through one or more processes. All CME content in this activity was independently reviewed to ensure that it is free of commercial bias, scientifically rigorous, aligned with the public interest, and compliant with all regulatory guidance and the ACCME’s Standards for Commercial Support of Continuing Medical Education.
In accordance with Accreditation Council for Continuing Medical Education requirements on disclosure, faculty and contributors are asked to disclose any relationships with commercial interests associated with the area of medicine featured in the activity. These relationships are described below.
Mark M. Awad, MD, PhD Clinical Director, Lowe Center for Thoracic Oncology Dana-Farber Cancer Institute Assistant Professor of Medicine Harvard Medical School Boston, MA
Dr. Awad discloses the following: Grant/Research Support: AstraZeneca; Bristol-Myers Squibb Company; Eli Lilly and Company; Genentech, Inc. Retained Consultant: AstraZeneca; Blueprint Medicine; Bristol-Myers Squibb Company; Genentech, Inc.; Merck & Co., Inc; Pfizer Inc.; Syndax
Alexander Drilon, MD Clinical Director Early Drug Development Service Memorial Sloan Kettering Cancer Center New York, NY
Dr. Drilon discloses the following: Retained Consultant: AstraZeneca; Bayer Healthcare; BeiGene; Blueprint Medicine Corporation; Exelixis, Inc.; Genentech, Inc./Roche; Helsinn Therapeutics; Hengrui Therapeutics Inc.; Ignyta; Loxo Oncology; Pfizer Inc.; TP Therapeutics, Inc.; Takeda Pharmaceutical Company Ltd. Honoraria: AstraZeneca; Bayer Healthcare; Foundation Medicine, Inc; Genentech, Inc./Roche; Medscape; MORE Health; OncLive; Peerview; PeerVoice; Physicians Education Resources; Research to Practice; Targeted Oncology; Tyra Biosciences
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Paradigm Medical Communications, LLC staff members have no financial relationships to disclose.
Peer Reviewer Disclosure
Independent peer reviewer has no financial relationships to disclose.
AMA PRA Category 1 Credit(s)TM
Paradigm Medical Communications, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Paradigm Medical Communications, LLC designates this enduring material for a maximum of 1.00 AMA PRA Category 1 CreditTM . Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Additional Credit Information
PA Continuing Education PAs may claim a maximum of 1.00 Category 1 credit for completing this activity. NCCPA accepts AMA PRA Category 1 CreditTM from organizations accredited by ACCME or a recognized state medical society.
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This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA.
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Disclaimer The materials provided for this activity are for informational purposes only, and should not be used for diagnosis or treatment of a health problem without consulting a licensed medical professional. Any views or opinions presented are solely those of the faculty, and do not necessarily represent those of Paradigm Medical Communications, LLC. References to any entity, product, service, or source of information on this website should not be considered an endorsement, either direct or implied, by Paradigm Medical Communications, LLC. Paradigm Medical Communications, LLC accepts no liability for the content referenced in this activity.
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Hardware/Software Requirements This certified CME activity is designed using HTML5. As you navigate the application using the supplied controls, the slides will present information via video, audio, text, images, or tables.
For Desktops (Windows/Mac) Internet Explorer 10 or higher, Firefox 28 or higher, Safari 9 or higher, Google Chrome 45 or higher, Opera 30 or higher
For Tablets (iPad/Android/Surface) iOS Safari 9 or higher, Android 4.4 or higher, IE Mobile 12 or higher