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Module 5: Assessment and Treatment Decisions in HIV/HCV Co-Infection

Module 5: Assessment and Treatment Decisions in HIV/HCV Co-Infection


Interactive Monograph

Time to Complete

1 hour


April 20, 2018


April 20, 2019

Educational Partner

This is Module 5 in the HealthHIV HIV Primary Care Training and Certificate Program.

Maximum Credits

1.00 / AMA PRA Category 1 CreditTM

Accredited Provider

This activity is jointly provided by Postgraduate Institute for Medicine and HealthHIV.

Commercial Supporter

This activity is not supported by educational grants.

Program Description

People with HIV infection are disproportionately affected by viral hepatitis. The CDC reports that in the United States, 25% of people living with HIV are co-infected with hepatitis C virus (HCV), and about 10% are co-infected with hepatitis B virus (HBV).

  • HCV co-infection is responsible for a five-fold increase in hospitalizations and has become a leading cause of complications and morality among people with HIV.
  • To better manage the risk of viral hepatitis in this population, people with HIV should be screened for HCV infection annually and before starting antiretroviral therapy (ART).1,2
  • HIV/HCV co-infections can be effectively managed in many people, but treatment is complex.
In this activity, you will learn how to how effectively identify at-risk patients and screen for HCV co-infection, select appropriate treatment plans, and gain a better understanding of the recommended guidelines for treating and managing HIV/HCV co-infection.

Module 5 of HealthHIV’s HIV Primary Care Training and Certificate Program is designed to build upon previous modules deepening primary care providers’ understanding of HIV epidemiology, diagnosis, and management by familiarizing them with recommended guidelines for treating and managing HIV/HCV co-infection.

Intended Audience

This activity has been designed to meet the educational needs of primary care physicians, and other allied healthcare professionals who treat and care for patients with HIV/AIDS.

Educational Objectives

After completing this activity, the participant will demonstrate the ability to:

  • Identify indications for the treatment of chronic HCV infection and reasons to consider delaying HCV treatment in patients with HIV/HCV co-infection
  • Explain the reported safety and efficacy of currently available treatments for HCV in patients co-infected with HIV
  • List HCV/HIV drug combinations to avoid based on potential for drug-drug interactions
  • Select guidelines-recommended monitoring for patients being treated for HCV/HIV co-infection

Disclosure of Conflicts of Interest

Postgraduate Institute of Medicine (PIM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest (COI) they may have as related to the content of this activity. All identified COI are thoroughly vetted and resolved according to PIM policy. PIM is committed to providing its learners with high quality CME activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of a commercial interest.


Christian B. Ramers, MD, MPH, AAHIVS
Assistant Medical Director – Research/Special Populations
Director – Graduate Medical Education
Family Health Centers of San Diego
Assistant Clinical Professor of Medicine
UC San Diego School of Medicine
San Diego, CA

Dr. Ramers discloses the following:
Consultant: Gilead Sciences, Bristol Myers-Squibb

Planners and Managers Disclosure

The PIM planners and managers, Trace Hutchinson, PharmD, Samantha Mattiucci, PharmD, CHCP, Judi Smelker-Mitchek, MBS, MSN, RN, and Jan Schultz, MSN, RN, CHCP, have nothing to disclose. The HealthHIV planners and managers Dana Cropper-Williams, Brian Hujdich, Sibyl Wilmont, and Michael Shankle, MPH, have nothing to disclose.




AMA PRA Category 1 Credit(s)TM

Accreditation Statement

In support of improving patient care, this activity has been planned and implemented by the Postgraduate Institute for Medicine and HealthHIV.  Postgraduate Institute for Medicine is jointly accredited by the American Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Designation Statement

The Postgraduate Institute for Medicine designates this enduring material for a maximum of 1.00 AMA PRA Category 1 Credit(s)TM  . Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

Disclosure of Unlabled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medication, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.




To obtain credit, a score of 80% or better on the post-test is required. This activity is offered at no cost to participants. Please proceed with the activity until you have successfully completed this program, answered all test questions, completed the post-test and evaluation, and have received a digital copy of your credit certificate. Your online certificate will be saved on myCME within your Profile/CME History, which you can access at any time.

Privacy Policy

Last Reviewed

This course originally launched 10/1/13 and was updated in January 2018.


Hardware and Software Requirements
  • A computer with an internet connection
  • Internet Browser: Internet Explorer 7.x or higher, Firefox 4.x or higher, Safari 2.x or higher, or any other W3C standards compliant browser
  • Additional Software: Adobe Flash Player and/or an HTML 5 capable browser maybe required for video or audio playback. PowerPoint or Adobe Acrobat Reader may occasionally be required
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