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Medical Crossfire®: Diagnostic and Management Challenges in Hyponatremia

Medical Crossfire®: Diagnostic and Management Challenges in Hyponatremia



Time to Complete

2 hours


September 20, 2016


September 20, 2017
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Maximum Credits

2.00 / AMA PRA Category 1 CreditsTM

Accredited Provider

This program is jointly provided by Global Education and Pharmacy Times Continuing Education.

Commercial Supporter

Supported by an educational grant from Otsuka America Pharmaceutical, Inc.

Program Description

There is a need to educate clinicians, pharmacists and hospital policy makers in the management of hyponatremia in hospitalized patients. Continuing professional education will increase awareness of evidence-based recommendations for the diagnosis and treatment of hyponatremia. The high rate of under-diagnosis and under-treatment provides opportunities for clinicians and pharmacists to improve outcomes and the quality of care for patients with hyponatremia. To do so, they need to be familiar with diagnostic algorithms and follow clinical practice guidelines for hyponatremia. Knowledge about medical practices that reduce the risk of osmotic demyelination syndrome can help prevent over-rapid correction of hyponatremia.

Intended Audience

Physicians, pharmacy directors, hospitalists, and health-system pharmacists

Educational Objectives

Upon completion of the activity, participants should be able to:

  • Distinguish new diagnostic algorithms and clinical practice guidelines for hyponatremia that can help improve the diagnosis and treatment of hospitalized patients with hyponatremia
  • Examine hyponatremia as a prognostic indicator in heart failure
  • Explore the role of vasopressin antagonists to correct hyponatremia and improve congestive symptoms in acute decompensated heart failure
  • Characterize the impact of hyponatremia on medical costs and pharmacoeconomic issues with vasopressin antagonists

Conflict Of Interest Disclosure Policy

Global Education Group (Global) requires instructors, planners, managers and other individuals and their spouse/life partner who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by Global for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.


Peter L. Salgo, MD
Professor of Medicine and Anesthesiology
Columbia University College of Physicians and Surgeons
New York, NY

Dr. Salgo has no relevant financial relationships with commercial interests to disclose.

Division of Critical Care and Neurohospitalist Program
Head of Neuroscience ICU
Head of Neurotrauma ICU
Director of Neuro Intermediate Unit
Memorial Hermann Texas Medical Center
Vice Chair and Associate Professor
Department of Neurosurgery
The University of Texas Houston Medical School
Houston, TX

Dr. Lee has no relevant financial relationships with commercial interests to disclose.

Jodie L. Pepin, PharmD
Department of Pharmacy
Seton Medical Center Williamson
Round Rock, Texas
Assistant Clinical Professor
College of Pharmacy
The University of Texas at Austin
Austin, TX

Dr. Pepin has no relevant financial relationships with commercial interests to disclose.

Joseph G. Verbalis, MD
Professor of Medicine
Chief, Endocrinology and Metabolism
Georgetown University Medical Center
Washington, D.C.

Dr. Verbalis has disclosed the following financial relationship with commercial interests:
Consultant: Otsuka America Pharmaceutical, Inc.

Accredited Provider Disclosures

The following contributors have no relevant financial relationships with commercial interests to disclose.

Global Education Group
Planning StaffKristen Delisi, NP, Amanda Glazar, PhD, Andrea Funk, and Laura Gilsdorf

Pharmacy Times Continuing Education
Planning StaffDavid Heckard and Maryjo Dixon, RPh




AMA PRA Category 1 Credit(s)TM

Accreditation Statement

Global Education Group is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Designation Statement

Global Education Group designates this enduring material for a maximum of 2.00 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by FDA. The opinions expressed in the educational activity are those of the faculty. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings. Further, attendees/participants should appraise the information presented critically and are encouraged to consult appropriate resources for any product or device mentioned in this program.


The content and views presented in this educational activity are those of the authors and do not necessarily reflect those of Global Education Group or Pharmacy Times Continuing Education. This material is prepared based on a review of multiple sources of information, but it is not exhaustive of the subject matter.

Therefore, health care professionals and other individuals should review and consider other publications and materials on the subject.


To obtain credit, a score of 70% or better on the post-test is required. This activity is offered at no cost to participants. Please proceed with the activity until you have successfully completed this program, answered all test questions, completed the post-test and evaluation, and have received a digital copy of your credit certificate. Your online certificate will be saved on myCME within your Profile/CME History, which you can access at any time.

For information about the accreditation of this program, please contact Global at 303-395-1782 or

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