Provided by Albert Einstein College of Medicine in collaboration with Haymarket Medical Education
Supported by an educational grant from Jazz Pharmaceuticals
The sheer pace of medical research challenges clinicians who try to keep up with the burgeoning volume of literature related to obstructive sleep apnea (OSA), narcolepsy, excessive daytime sleepiness, and other sleep-related disorders. The Keeping Up With Sleep Journal Club selects key articles and shares expert commentary on them, giving learners an educational tool that helps translate emerging knowledge into improvements in clinical care. This issue addresses multiple sleep-latency test results that change over time in narcolepsy type 2; the neurochemical and behavior effects of solriamfetol; the impact of “overlap syndrome”—comorbid OSA and chronic obstructive pulmonary disease; the associations among OSA, hypertension, and other elements of the metabolic syndrome; and a trial of sodium oxybate in a pediatric population.
Psychiatrists, neurologists, pulmonologists, sleep specialists, and other clinicians who treat patients with or who are at risk for sleep-related disorders
After completing the activity, the participant should be better able to:
Characterize the impact of excessive daytime sleepiness (EDS) on patients’ health, ability to function, and quality of life
Recognize signs and symptoms of EDS in patients with obstructive sleep apnea, narcolepsy, and other disorders related to sleep disturbances
Evaluate new and emerging developments in the assessment and management of EDS
Conflict Of Interest Disclosure Policy
In accordance with the ACCME Standards for Commercial Support, Albert Einstein School of Medicine requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. Albert Einstein School of Medicine resolves all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational activities.
CHAIR Michael J. Thorpy, MB, ChB Professor of Neurology Albert Einstein College of Medicine Bronx, NY
Dr. Thorpy has served on the speakers’ bureaus for Jazz Pharmaceuticals and Merck & Co., Inc. He has also has conducted research funded by Balance Therapeutics, Flamel Technologies, and Jazz Pharmaceuticals.
FACULTY Richard K. Bogan, MD, FCCP, FAASM Chief Medical Officer, SleepMed, Inc. Clinical Associate Professor, Medical University of South Carolina Clinical Associate Professor, University of South Carolina Columbia, SC
Dr. Bogan has been a consultant for Harmony Biosciences and Jazz Pharmaceuticals and has served on the speakers’ bureau for Jazz Pharmaceuticals. He has also conducted research funded by Avadel Pharmaceuticals, Harmony Biosciences, and Jazz Pharmaceuticals.
Thomas E. Scammell, MD Professor of Neurology Beth Israel Deaconess Medical Center Harvard Medical School Boston, MA
Dr. Scammell has been a consultant for Avadel Pharmaceuticals, Balance Therapeutics, Bioprojet, Harmony Biosciences, Jazz Pharmaceuticals, Merck & Co., Inc., Takeda, and Vertex Pharmaceuticals. He has also conducted research funded by Merck & Co., Inc. and Takeda.
CME PEER REVIEWERS Imran Ahmed, MD Program Director, Sleep Medicine Training Program Associate Professor of Clinical Neurology Associate Director, Sleep-Wake Disorders Center Albert Einstein College of Medicine Montefiore Medical Center Bronx, NY
Dr. Ahmed is a principal investigator in a pediatric study with Xyrem.
Victor Hatcher, PhD Associate Dean for Continuing Medical Education and Research Administration Professor, Department of Biochemistry Professor, Department of Medicine Albert Einstein College of Medicine Montefiore Medical Center Bronx, NY
Dr. Hatcher has no relevant financial relationships to disclose.
Accredited Provider Disclosures
The Albert Einstein School of Medicine and Haymarket Medical Education staff involved in the planning and content review of this activity have no relevant financial relationships to disclose.
AMA PRA Category 1 Credit(s)TM
Albert Einstein School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Albert Einstein College of Medicine designates this enduring material for a maximum of 0.75 AMA PRA Category 1 CreditTM . Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Additional Credit Information
Physician Assistant Continuing Education AAPA accepts certificates of participation for educational activities certified for AMA PRA Category 1 CreditTM from organizations accredited by ACCME or a recognized state medical society. PAs may receive a maximum of 0.75 Category 1 Credit for completing this activity.
Nurse Practitioner Continuing Education The American Academy of Nurse Practitioners Certification Program (AANPCP) accepts certificates of participation for educational activities certified for AMA PRA Category 1 CreditTM from organizations accredited by ACCME. Individuals are responsible for checking with the AANPCP for further guidelines.
Disclosure of Unlabeled Use
This CME activity may or may not discuss investigational, unapproved, or off-label use of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME activity is for continuing medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options for a specific patient’s medical condition.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of Jazz Pharmaceuticals, Albert Einstein School of Medicine, or Haymarket Medical Education. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
To obtain credit, a score of 70% or better on the post-test is required. This activity is offered at no cost to participants. Please proceed with the activity until you have successfully completed this program, answered all test questions, completed the post-test and evaluation, and have received a digital copy of your credit certificate. Your online certificate will be saved on myCME within your Profile/CME History, which you can access at any time.