Weight Loss May Cut Breast CA Risk in Postmenopausal Women

Share this content:
Weight Loss May Cut Breast CA Risk in Postmenopausal Women
Weight Loss May Cut Breast CA Risk in Postmenopausal Women

TUESDAY, Oct. 9, 2018 (HealthDay News) -- Postmenopausal women with weight loss have a reduced risk for breast cancer, according to a study published online Oct. 8 in Cancer.

Rowan T. Chlebowski, M.D., Ph.D., from the City of Hope National Medical Center in Duarte, Calif., and colleagues examined the correlation between weight change and breast cancer risk in 61,335 postmenopausal women with no prior breast cancer and a normal mammogram. Body weight and height were measured and body mass index (BMI) was calculated at baseline and year three; weight change was classified as stable (<5 percent), loss (≥5 percent), or gain (≥5 percent).

The researchers identified 3,061 incident breast cancers during a mean follow-up of 11.4 years. Compared with women whose weight remained stable, those with weight loss had a significantly lower risk for breast cancer (hazard ratio, 0.88; 95 percent confidence interval, 0.78 to 0.98) with no interaction by BMI. The findings were not altered by adjustment for mammography (hazard ratio, 0.88; 95 percent confidence interval, 0.78 to 0.99), with no significant difference by weight loss intentionality. There was no significant correlation between weight gain and breast cancer risk (hazard ratio, 1.02; 95 percent confidence interval, 0.93 to 1.11); weight gain correlated with a higher incidence of triple-negative breast cancer (hazard ratio, 1.54; 95 percent confidence interval, 1.16 to 2.05).

"These findings suggest that postmenopausal women who lose weight may reduce their breast cancer risk," the authors write.

One author disclosed financial ties to the pharmaceutical industry.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: More Cases in Salmonella Outbreak Linked to Recalled Beef

CDC: More Cases in <i>Salmonella</i> Outbreak Linked to ...

Three more states have reported illnesses; 87 new cases include 32 people who have been hospitalized

Eligibility Criteria Limit Access to Arthroplasty for Minorities

Eligibility Criteria Limit Access to Arthroplasty for Minorities

Those with lower socioeconomic status, lower education level have reduced odds of being eligible

is free, fast, and customized just for you!




Already a member?

Sign In Now »