Vitamin D Supplementation Cuts Aeroallergen Sensitization

This article originally appeared here.
Share this content:
Vitamin D Supplementation Cuts Aeroallergen Sensitization
Vitamin D Supplementation Cuts Aeroallergen Sensitization

MONDAY, April 18, 2016 (HealthDay News) -- Vitamin D supplementation during pregnancy and infancy may reduce aeroallergen sensitization in children, according to a study published online April 6 in Allergy.

Cameron C. Grant, M.B.Ch.B., from the University of Auckland in New Zealand, and colleagues conducted a randomized, double-blind, placebo controlled trial. Pregnant women (27 weeks of gestation to birth) and then their infants were randomized to receive placebo or one of two doses of daily oral vitamin D (placebo/placebo; 1,000 IU/400 IU; 2,000 IU/800 IU). Specific serum immunoglobulin (Ig)E antibodies were measured when the children were 18 months old.

Specific IgE was measured in 71 percent of 260 enrolled children. The researchers found that for four mite antigens: Dermatophagoides farina (Der-f1, Der-f2) and Dermatophagoides pteronyssinus (Der-p1, Der-p2), the proportion of children sensitized varied for placebo, lower-dose, and higher-dose vitamin D, respectively: 18, 10, 2 percent; 14, 3, 2 percent; 19, 14, 3 percent; and 12, 2, 3 percent, respectively (all P < 0.05). Study group differences were seen in the proportion of children with primary care visits for asthma (11, 0, 4 percent, respectively; P = 0.002), but not for other respiratory diagnoses.

"Vitamin D supplementation during pregnancy and infancy reduces the proportion of children sensitized to mites at age 18 months," the authors write. "Preliminary data indicate a possible effect on primary care visits where asthma is diagnosed."

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Zika, West Nile Cases Reported in Alabama

Zika, West Nile Cases Reported in Alabama

State health officials note that Zika hasn't been transmitted locally

TBI Linked to Increased Suicide Risk

TBI Linked to Increased Suicide Risk

Increased suicide risk with one, two, and three or more medical contacts for traumatic brain injury

Triple Combo Blood Pressure Pill Can Improve BP Control

Triple Combo Blood Pressure Pill Can Improve BP ...

Proportion achieving target BP increased with use of triple combo pill versus usual care at six months

is free, fast, and customized just for you!




Already a member?

Sign In Now »