Vitamin A Appears Helpful in Pediatric Retinitis Pigmentosa

Share this content:
Vitamin A Appears Helpful in Pediatric Retinitis Pigmentosa
Vitamin A Appears Helpful in Pediatric Retinitis Pigmentosa

MONDAY, April 2, 2018 (HealthDay News) -- For children with retinitis pigmentosa, vitamin A supplementation is associated with slower loss of cone electroretinogram amplitude, according to a study published online March 29 in JAMA Ophthalmology.

Eliot L. Berson, M.D., from Harvard Medical School in Boston, and colleagues conducted a nonrandomized comparison study involving children with retinitis pigmentosa taking or not taking vitamin A supplementation (55 and 25, respectively). The main outcome was the mean exponential rates of change of full-field cone electroretinogram amplitude to 30-Hz flashes.

The researchers found that in the unadjusted model, the estimated mean rates of change were −0.0713 loge unit/year for the vitamin A cohort and −0.1419 loge unit per year for the control cohort (−6.9 and −13.2 percent per year, respectively). A slower mean rate of decline was confirmed in the vitamin A cohort in the adjusted model (difference, 0.0771 loge-unit per year). There was no difference by cohort in the mean exponential rates of change of visual field area and visual acuity and the incidences of falling to a visual field diameter of 20 degrees or less or a visual acuity of 20/200 or less in at least one eye.

"A vitamin A palmitate supplement was associated with a slower loss of cone electroretinogram amplitude in children with retinitis pigmentosa," the authors write.

Abstract/Full Text
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

E. Coli Found in Water at Tennessee Ziplining Facility

<i>E. Coli</i> Found in Water at Tennessee Ziplining ...

One visitor to the CLIMB Works Zipline Canopy Tour in Gatlinburg tested positive for norovirus and E. coli

FDA: Illnesses Tied to Fresh Crab Meat Imported From Venezuela

FDA: Illnesses Tied to Fresh Crab Meat Imported ...

Illnesses appear to be caused by Vibrio parahaemolyticus bacteria

FDA Approves First Drug to Treat Smallpox

FDA Approves First Drug to Treat Smallpox

New treatment offers additional option should smallpox ever be used as a bioweapon

is free, fast, and customized just for you!




Already a member?

Sign In Now »