Vascular Targeted Photodynamic Tx Aids Low-Risk Prostate Cancer

This article originally appeared here.
Share this content:
Vascular Targeted Photodynamic Tx Aids Low-Risk Prostate Cancer
Vascular Targeted Photodynamic Tx Aids Low-Risk Prostate Cancer

TUESDAY, July 25, 2017 (HealthDay News) -- For men with low-risk prostate cancer, vascular targeted photodynamic therapy achieves an 82 percent rate of absent clinically significant cancer in treated lobes, according to a study published in the August issue of The Journal of Urology.

Souhil Lebdai, M.D., from the University Hospital of Angers in France, and colleagues followed 82 men treated with vascular targeted photodynamic therapy for low-risk prostate cancer every six months. Six months after treatment or when there was biological or clinical progression, patients underwent prostate biopsies.

Patients were followed for a median of 68 months. The researchers found that median progression-free survival was 86 months. Six months after treatment, there was a significant 41 percent decrease in median prostate-specific antigen, which remained stable during follow-up (P < 0.001). One hundred fifteen lobes were treated and 82 percent achieved absent clinically significant cancer. Twenty of the patients (24 percent) underwent radical therapy, including 18 and two patients who underwent radical prostatectomy and brachytherapy, respectively, at a median of 22 months.

"Padeliporfin vascular targeted photodynamic therapy for low-risk prostate cancer achieved an 82 percent rate of absent clinically significant cancer in treated lobes and 76 percent of patients avoided radical therapy at a median follow-up of 68 months," the authors write. "However, longer term follow-up is required to determine long-term outcomes."

One author disclosed financial ties to Steba Biotech, which funded the study.

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Permits Marketing of Brain Stimulation Device for OCD

FDA Permits Marketing of Brain Stimulation Device for ...

FDA previously approved transcranial magnetic stimulation for major depression, certain migraines

Comments Open on End of NIH Review for Gene Therapy Studies

Comments Open on End of NIH Review for ...

NIH oversight panel no longer plans to review all applications for gene therapy experiments

U.S. Measles Outbreak Hits 107 Cases in 21 States, D.C.

U.S. Measles Outbreak Hits 107 Cases in 21 ...

Outbreak on track to exceed last year's; most of the people who got measles weren't vaccinated

is free, fast, and customized just for you!




Already a member?

Sign In Now »