Ultrasound for Rectal Cancer Staging Tied to More Chemoradiation

This article originally appeared here.
Share this content:
Ultrasound for Rectal Cancer Staging Tied to More Chemoradiation
Ultrasound for Rectal Cancer Staging Tied to More Chemoradiation

MONDAY, Feb. 12, 2018 (HealthDay News) -- Use of endoscopic ultrasound (EUS) for rectal cancer (RC) staging is associated with higher use of neoadjuvant chemoradiation but no significant improvement in overall survival, according to a study published Jan. 26 in the Journal of Gastroenterology and Hepatology.

Philip N. Okafor, M.D., M.P.H., from Stanford University in California, and colleagues used the Surveillance, Epidemiology, and End Results-Medicare database to identify 3,408 patients with nonmetastatic RC between 2005 and 2007. Outcomes were compared between patients who received EUS and computed tomography of the abdomen and pelvis (CTAP) to those staged with CTAP alone.

The researchers found that compared to patients staged with CTAP alone, those who received EUS and CTAP were younger, were more likely male, and had a lower Charlson comorbidity index. Higher socioeconomic status (odds ratio [OR], 1.87), care by a gastroenterologist (OR, 1.713), and care in a teaching hospital (OR, 1.68) predicted EUS. Patients staged with EUS received more neoadjuvant chemoradiation. There was a trend toward longer survival among EUS-staged patients versus those staged with CTAP alone (60 versus 57 months), but this was not statistically significant.

"EUS in RC staging is associated with higher utilization of neoadjuvant chemoradiation without a significant difference in overall survival," conclude the authors.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Patient-Reported Outcome Measures May Aid Communication

Patient-Reported Outcome Measures May Aid Communication

Usefulness of PROs varies based on how much doctors value, prioritize, and use them

Negative Attitudes Reported Toward Weight-Loss Surgery

Negative Attitudes Reported Toward Weight-Loss Surgery

Women more likely to think surgery is needed for health, less likely to consider it 'easy way out'

Risk for Hospitalization for Heart Failure Greater With Diabetes

Risk for Hospitalization for Heart Failure Greater With ...

Rate has declined but remains higher in those with type 1 or 2 diabetes than in those without

is free, fast, and customized just for you!




Already a member?

Sign In Now »