Tool May Predict Short-Term Progression to Type 1 Diabetes

This article originally appeared here.
Share this content:
Tool May Predict Short-Term Progression to Type 1 Diabetes
Tool May Predict Short-Term Progression to Type 1 Diabetes

FRIDAY, March 20, 2015 (HealthDay News) -- Researchers have developed a new tool that may predict short-term glycemic progression to type 1 diabetes (T1D). The findings were published online March 10 in Diabetes Care.

Jay M. Sosenko, M.D., from the University of Miami, and colleagues utilized Diabetes Prevention Trial-Type 1 (DPT-1) data to develop and test a scale to serve as a potential end point for six-month glycemic progression (PS6M) toward type 1 diabetes (T1D) in autoantibody-positive relatives of individuals with T1D.

The researchers found that PS6M significantly predicted T1D (P < 0.001). Compared to the baseline-to-six-month difference in glucose, the area under the receiver operating characteristic curve was greater (P < 0.001) for the PS6M. In those with two or more autoantibodies, PS6M values were higher (30-0 min C-peptide values <2.00 ng/mL, or DPT-1 Risk Scores >7.00; P < 0.001 for all).

"The PS6M is an indicator of short-term glycemic progression to T1D that could be a useful tool for assessing preventive treatments and biomarkers," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Permits Marketing of Brain Stimulation Device for OCD

FDA Permits Marketing of Brain Stimulation Device for ...

FDA previously approved transcranial magnetic stimulation for major depression, certain migraines

Comments Open on End of NIH Review for Gene Therapy Studies

Comments Open on End of NIH Review for ...

NIH oversight panel no longer plans to review all applications for gene therapy experiments

U.S. Measles Outbreak Hits 107 Cases in 21 States, D.C.

U.S. Measles Outbreak Hits 107 Cases in 21 ...

Outbreak on track to exceed last year's; most of the people who got measles weren't vaccinated

is free, fast, and customized just for you!




Already a member?

Sign In Now »