Sufficient Preconception Vitamin D Tied to Lower Miscarriage Risk

Share this content:
Sufficient Preconception Vitamin D Tied to Lower Miscarriage Risk
Sufficient Preconception Vitamin D Tied to Lower Miscarriage Risk

FRIDAY, Aug. 10, 2018 (HealthDay News) -- Preconception vitamin D levels may play a role in maintaining pregnancy, according to a study published recently in The Lancet Diabetes & Endocrinology.

Sunni Mumford, Ph.D., from the National Institutes of Health in Bethesda, Md., and colleagues conducted a secondary analysis of data from the EAGeR trial to assess the association between preconception vitamin D and pregnancy outcomes among 1,191 women with proven fecundity. Serum 25-hydroxyvitamin D was measured preconception (baseline) and at 8 weeks gestation.

The researchers found that 555 women (47 percent) were classified as having sufficient concentrations (≥75 nmol/L) while 636 (53 percent) had insufficient concentrations (<75 nmol/L). Clinical pregnancy was more likely among women with sufficient preconception 25-hydroxyvitamin D (adjusted risk ratio [RR], 1.10) and livebirth (adjusted RR, 1.15) versus women with insufficient concentrations. Among women who achieved pregnancy, sufficient preconception 25-hydroxyvitamin D was associated with reduced risk of pregnancy loss (preconception RR per 25 nmol/L, 0.88; 95 percent confidence interval, 0.77 to 0.99); but this was not found at 8 weeks of gestation (RR, 0.98; 95 percent confidence interval, 0.95 to 1.01).

"These results provide valuable insight into the potential effects of vitamin D during the preconception period for fertile or subfertile couples attempting spontaneous conception," the authors write.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

WPSI Recommends Annual Urinary Incontinence Screening

WPSI Recommends Annual Urinary Incontinence Screening

Due to limited evidence, other experts urge caution in implementing guideline for women

Young, Growing Athletes at High Risk for ACL Injuries

Young, Growing Athletes at High Risk for ACL ...

Athletic teams should provide program that includes muscle strengthening, proper technique training

Side Effects of Biologics for Rheumatic Dz May Up Anxiety

Side Effects of Biologics for Rheumatic Dz May ...

Common patient concerns are risks of cancer and tuberculosis activation

is free, fast, and customized just for you!




Already a member?

Sign In Now »