Study Compares Outcomes for Fresh, Cryopreserved Oocytes

Share this content:
Study Compares Outcomes for Fresh, Cryopreserved Oocytes
Study Compares Outcomes for Fresh, Cryopreserved Oocytes

TUESDAY, Aug. 11, 2015 (HealthDay News) -- In vitro fertilization (IVF) with cryopreserved donor oocytes has lower cancellation rates and lower live birth rates compared with donor cycles using fresh oocytes, according to a research letter published in the Aug. 11 issue of the Journal of the American Medical Association.

Using data from the 2013 annual report of U.S. IVF center outcomes published by the Society for Assisted Reproductive Technology, Vitaly A. Kushnir, M.D., from the Center for Human Reproduction in New York City, and colleagues compared live birth and cycle cancellation rates for fresh and cryopreserved donor oocytes. The aggregate data set was based on center-specific voluntarily reported outcomes from 380 U.S. fertility centers.

The researchers found that 20.0 percent of 11,148 oocyte donation cycles involved use of cryopreserved donor oocytes. Initiated cycles were cancelled in 11.7 and 8.5 percent of cycles involving fresh oocytes and cryopreserved oocytes, respectively (P < 0.001). The live birth rates were 49.6 and 43.2 percent with fresh and cryopreserved oocytes, respectively, per started recipient cycle (P < 0.001), and 56.1 and 47.1 percent, respectively, per embryo transfer (P < 0.001). Patients using fresh versus cryopreserved oocytes had a mean of 1.7 versus 1.6 embryos (P = 0.001).

"Even though these data offer new information about use of cryopreserved oocytes in donation cycles, they also demonstrate the need for additional studies," the authors write.

Several authors disclosed financial ties to Fertility Nutraceuticals. One author was the owner of the Center for Human Reproduction.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Cognitive Disability Most Prevalent Type in Young Adults

Cognitive Disability Most Prevalent Type in Young Adults

Disability-specific disparities prevalent in access to health care, especially for young, middle-aged adults

Declines in Life Expectancy in Many High-Income Countries

Declines in Life Expectancy in Many High-Income Countries

And increase in midlife death rates across racial and ethnic groups in the United States

Tobacco Content Still Common on U.K. Prime-Time Television

Tobacco Content Still Common on U.K. Prime-Time Television

Tobacco content occurred in 33 percent of all programs; 8 percent of all adverts, trailer breaks

is free, fast, and customized just for you!




Already a member?

Sign In Now »