Stem/Progenitor Cells Can Predict Wound Healing

This article originally appeared here.
Share this content:
Stem/Progenitor Cells Can Predict Wound Healing
Stem/Progenitor Cells Can Predict Wound Healing

TUESDAY, Nov. 3, 2015 (HealthDay News) -- Stem/progenitor cell (SPC) assays can predict wound healing in diabetic foot ulcers (DFUs), according to a study published online Oct. 20 in Diabetes.

Stephen R. Thom, M.D., Ph.D., from the University of Maryland School of Medicine in Baltimore, and colleagues collected blood and debrided wound margins for eight weeks from 100 patients undergoing weekly evaluations and treatment. They examined SPC number and intracellular content of hypoxia inducible factors (HIFs).

The researchers found that in the first two weeks of care, more SPCs entered the bloodstream in patients who healed (37 patients) than those who did not (63 patients). The number of bloodborne SPCs and cellular content of HIFs at study entry and first week follow-up visit predicted healing. Among week-to-week assessment of bloodborne SPC's HIF factors, strong correlations were identified.

"We conclude that assays of SPCs during the first weeks of care in patients with DFUs can provide insight into how well wounds will respond, and may aid with decisions on use of adjunctive measures," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Dozens of Medical Groups Join Forces to Improve Diagnoses

Dozens of Medical Groups Join Forces to Improve ...

Diagnostic error is the most common cause of medical errors that patients report

HbA1c Variability Is a Strong Predictor of Mortality in T2DM

HbA1c Variability Is a Strong Predictor of Mortality ...

HbA1c variability is a powerful, independent measure, regardless of how it is measured

Pediatric End-Stage Liver Disease Score Underestimates Mortality

Pediatric End-Stage Liver Disease Score Underestimates Mortality

Actual probability of death for patients on liver transplant wait list underestimated by up to 17%

is free, fast, and customized just for you!




Already a member?

Sign In Now »