Spermatogenesis Still Occurs in Men With Testicular Cancer

Share this content:
Spermatogenesis Still Occurs in Men With Testicular Cancer
Spermatogenesis Still Occurs in Men With Testicular Cancer

FRIDAY, April 27, 2018 (HealthDay News) -- Spermatogenesis occurs in most men with testicular cancer, often away from tumors, according to a study published online April 17 in BJU International.

Jemma A. Moody, from King's College London, and colleagues retrospectively reviewed 103 testicular germ cell tumors (TGCTs) in men who underwent radical orchidectomy (between 2011 and 2015) in order to assess the frequency and predictors of spermatogenesis.

The researchers found that spermatogenesis was present in 70 percent of the patients. Spermatogenesis was widespread in 63 percent of these patients and focal in 38 percent. Tumor type, stage, presence of microcalcification, and tumor markers did not predict spermatogenesis. Spermatogenesis was 82 percent less likely among men with a percentage testis tumor occupation of >50 percent of their testis versus those with a percentage testis tumor occupation of <50 percent.

"These findings can help predict and guide successful surgical sperm retrieval in testes with TGCTs," the authors write. "The finding of focal spermatogenesis in a third of patients would support a microsurgical approach to sperm retrieval at the time of orchidectomy to maximize success."

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: Progress in HIV Prevention Has Stalled in the United States

CDC: Progress in HIV Prevention Has Stalled in ...

Agency says effective HIV prevention, treatment not reaching those who could most benefit

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in Children

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in ...

All children with sustained unresponsiveness ingested concentrated and baked egg

Prenatal Vitamin Intake in Early Pregnancy May Cut Autism Risk

Prenatal Vitamin Intake in Early Pregnancy May Cut ...

ASD risk down for children whose mothers took prenatal vitamins during first month of pregnancy

is free, fast, and customized just for you!




Already a member?

Sign In Now »