Sodium Intake, BP Linked in Communities With Highest Intake

Share this content:
Sodium Intake, BP Linked in Communities With Highest Intake
Sodium Intake, BP Linked in Communities With Highest Intake

THURSDAY, Aug. 23, 2018 (HealthDay News) -- Mean systolic blood pressure is increased with increasing sodium intake only in communities in the highest tertile of sodium intake, according to a study published online Aug. 9 in The Lancet.

Andrew Mente, Ph.D., from McMaster University in Hamilton, Canada, and colleagues performed an analysis of the Prospective Urban Rural Epidemiology study in 18 countries to examine the correlations between community-level mean sodium and potassium intake, cardiovascular disease, and mortality. BP was assessed for 95,767 participants in 369 communities, and cardiovascular outcomes were assessed among 82,544 participants in 255 communities.

The researchers found that there was an increase in mean systolic BP of 2.86 mmHg per 1 g increase in mean sodium intake; only communities in the highest tertile of sodium intake had positive correlations. Significant deviations from linearity were seen for the correlation between mean sodium intake and major cardiovascular events; this resulted from a significant inverse association in the lowest tertile of sodium intake (change, −1 events per 1,000 years; 95 percent confidence interval, −2 to −0.1), no association in the middle tertile (change, 0.24 events per 1,000 years; 95 percent confidence interval, −2.12 to 2.61), and a positive but non-significant association in the highest tertile (change, 0.37 events per 1,000 years; 95 percent confidence interval, −0.03 to 0.78). Compared with other countries, in China there was a strong association with stroke (mean sodium intake, 5.58 mg/day; 0.42 events per 1,000 years).

"Sodium intake was associated with cardiovascular disease and strokes only in communities where mean intake was greater than 5 g/day," the authors write.

The study was funded in part by pharmaceutical companies.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: Increase Seen in Salmonella Illnesses From Ground Beef

CDC: Increase Seen in <i>Salmonella</i> Illnesses From Ground ...

246 people now sickened; 59 people have been hospitalized; no deaths reported to date

Epinephrine Personal Autoinjectors Cost-Effective at 24

Epinephrine Personal Autoinjectors Cost-Effective at &#36;24

Based on 10-fold fatality risk difference, value-based price for personal epinephrine $24

Burden of Liver Cancer Rising in Medicare Patients

Burden of Liver Cancer Rising in Medicare Patients

Coexistence of other liver conditions tied to even higher risk for death, health care costs

is free, fast, and customized just for you!




Already a member?

Sign In Now »