Single Blood Sample Test May Help ID Undiagnosed Diabetes

Share this content:
Single Blood Sample Test May Help ID Undiagnosed Diabetes
Single Blood Sample Test May Help ID Undiagnosed Diabetes

MONDAY, June 18, 2018 (HealthDay News) -- Single-sample confirmatory testing for diabetes has a high positive predictive value for subsequent diagnosis, according to a study published online June 19 in the Annals of Internal Medicine.

Elizabeth Selvin, Ph.D., M.P.H., from the Johns Hopkins Bloomberg School of Public Health in Baltimore, and colleagues examined the prognostic performance of a single-sample confirmatory definition of undiagnosed diabetes among 12,268 participants in the Atherosclerosis Risk in Communities study without diagnosed diabetes at baseline and with 25 years of follow-up for incident diabetes, cardiovascular outcomes, kidney disease, and mortality.

The researchers found that 978 participants had elevated levels of fasting glucose or HbA1c at baseline and that, of these, 39 percent had both measures elevated (confirmed undiagnosed diabetes), while 61 percent had only one elevated measure (unconfirmed undiagnosed diabetes). For identification of diabetes cases diagnosed during the first five years of follow-up, the confirmatory definition had moderate sensitivity (54.9 percent) but high specificity (98.1 percent), which increased to 99.6 percent by 15 years. The 15-year positive predictive value was 88.7 percent versus 71.1 percent for unconfirmed cases.

"Our results support the clinical utility of using a combination of elevated fasting glucose and HbA1c levels from a single blood sample to identify undiagnosed diabetes in the population," the authors write.

One author disclosed financial ties to the biotechnology industry.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: Progress in HIV Prevention Has Stalled in the United States

CDC: Progress in HIV Prevention Has Stalled in ...

Agency says effective HIV prevention, treatment not reaching those who could most benefit

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in Children

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in ...

All children with sustained unresponsiveness ingested concentrated and baked egg

Prenatal Vitamin Intake in Early Pregnancy May Cut Autism Risk

Prenatal Vitamin Intake in Early Pregnancy May Cut ...

ASD risk down for children whose mothers took prenatal vitamins during first month of pregnancy

is free, fast, and customized just for you!




Already a member?

Sign In Now »