Short-Term Benefits for Immunothx in Allergic Asthma

This article originally appeared here.
Share this content:
Short-Term Benefits for Immunothx in Allergic Asthma
Short-Term Benefits for Immunothx in Allergic Asthma

FRIDAY, June 2, 2017 (HealthDay News) -- Administration of allergen immunotherapy (AIT) in patients with allergic asthma leads to lower short-term symptom and medication scores, according to a review published online May 19 in Allergy.

Sangeeta Dhami, M.B.B.S., from Evidence-Based Health Care in Edinburgh, U.K., and colleagues performed a systematic review to examine evidence on the effectiveness, cost-effectiveness, and safety of AIT. Data were reviewed from 98 studies.

The researchers observed a reduction in short-term symptom and medication scores, with evidence found for publication bias. No reduction was seen in short-term combined medication and symptom scores; a beneficial long-term effect was seen in one study. Subcutaneous immunotherapy correlated with improved quality of life and reduction in allergen-specific airway hyperreactivity (AHR); this was not seen for sublingual immunotherapy (SLIT). No consistent effects were seen on asthma control, exacerbations, lung function, or non-specific AHR. There was a modest increase in the risk of adverse events with AIT. Evidence on cost-effectiveness was mainly available for SLIT, which was likely to be cost-effective.

"AIT can achieve substantial reductions in short-term symptom and medication scores in allergic asthma," the authors write. "More data are needed in relation to secondary outcomes, longer-term effectiveness, and cost-effectiveness."

Several authors disclosed financial ties to the biopharmaceutical industry.

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC Warns of Polio-Like Virus Striking More U.S. Children

CDC Warns of Polio-Like Virus Striking More U.S. ...

127 cases reported in 22 states so far this year with 62 confirmed as acute flaccid myelitis

Harvard: Heart Researcher's Papers Contain Fraudulent Data

Harvard: Heart Researcher's Papers Contain Fraudulent Data

31 scientific publications from the laboratory of Piero Anversa contain falsified and/or fabricated data

Bariatric Sx Cuts Macrovascular Complications in Obesity, T2DM

Bariatric Sx Cuts Macrovascular Complications in Obesity, T2DM

Lower composite incidence of macrovascular events, lower incidence of coronary artery disease at 5 years

is free, fast, and customized just for you!




Already a member?

Sign In Now »