Sentinel Lymph Node Mapping Most Cost-Effective for Uterine CA

Share this content:
Sentinel Lymph Node Mapping Most Cost-Effective for Uterine CA
Sentinel Lymph Node Mapping Most Cost-Effective for Uterine CA

TUESDAY, Aug. 21, 2018 (HealthDay News) -- Sentinel lymph node mapping has the lowest costs and highest quality-adjusted survival compared to both routine and selective lymphadenectomy for managing low-risk endometrial carcinoma, according to a study published in the July issue of Obstetrics & Gynecology.

Rudy S. Suidan, M.D., from the University of Texas MD Anderson Cancer Center in Houston, and colleagues evaluated the cost-utility of three lymphadenectomy strategies (routine lymphadenectomy in all patients, selective lymphadenectomy based on intraoperative frozen section criteria, and sentinel lymph node mapping) in the management of low-risk endometrial carcinoma.

The researchers found in the base-case scenario that routine lymphadenectomy had a cost of $18,041 and an effectiveness of 2.79 quality-adjusted life-years (QALYs) versus $17,036 and 2.81 QALYs with selective lymphadenectomy and $16,401 and 2.87 QALYS with sentinel lymph node mapping. Selective lymphadenectomy was both less costly and more effective than routine lymphadenectomy. But sentinel lymph node mapping dominated the other modalities and was the most cost-effective strategy. These findings remained even when varying the rates of lymphedema and lymphadenectomy, surgical approach (open or minimally invasive surgery), lymphedema utility, and costs.

"For the estimated 40,000 women undergoing surgery for low-risk endometrial carcinoma each year in the United States, the annual cost of routine lymphadenectomy, selective lymphadenectomy, and sentinel lymph node mapping would be $722 million, $681 million, and $656 million, respectively," the authors write.

Several authors disclosed financial ties to the pharmaceutical industry.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: Progress in HIV Prevention Has Stalled in the United States

CDC: Progress in HIV Prevention Has Stalled in ...

Agency says effective HIV prevention, treatment not reaching those who could most benefit

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in Children

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in ...

All children with sustained unresponsiveness ingested concentrated and baked egg

Prenatal Vitamin Intake in Early Pregnancy May Cut Autism Risk

Prenatal Vitamin Intake in Early Pregnancy May Cut ...

ASD risk down for children whose mothers took prenatal vitamins during first month of pregnancy

is free, fast, and customized just for you!




Already a member?

Sign In Now »