Secukinumab Effective for Moderate/Severe Scalp Psoriasis

Share this content:
Secukinumab Effective for Moderate/Severe Scalp Psoriasis
Secukinumab Effective for Moderate/Severe Scalp Psoriasis

FRIDAY, Sept. 29, 2017 (HealthDay News) -- Secukinumab is safe and effective as a treatment for patients with extensive moderate-to-severe scalp psoriasis, according to a study published in the October issue of the Journal of the American Academy of Dermatology.

Jerry Bagel, M.D., from the Psoriasis Treatment Center of Central New Jersey in East Windsor, and colleagues conducted a 24-week, double-blind, phase 3b study in which 102 patients were randomized to subcutaneous secukinumab (300 mg) or placebo at baseline; weeks 1, 2, and 3; and then every four weeks from week 4 to 20.

The researchers found that at week 12, 90 percent improvement of the Psoriasis Scalp Severity Index score was seen in 52.9 percent of the secukinumab group versus 2 percent of the placebo group. In addition, Investigator's Global Assessment modified 2011 scalp responses of 0 or 1 were 56.9 percent and 5.9 percent, respectively, with secukinumab and placebo. Significantly more patients achieved complete clearance of scalp psoriasis at week 12 with secukinumab 300 mg compared with placebo (35.3 percent versus 0 percent. The safety of secukinumab was consistent with other phase 3 studies.

"Secukinumab is efficacious and well-tolerated for patients with extensive moderate-to-severe scalp psoriasis," conclude the authors.

Several authors disclosed financial ties to pharmaceutical companies, including Novartis Pharmaceuticals, which funded the study.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: Progress in HIV Prevention Has Stalled in the United States

CDC: Progress in HIV Prevention Has Stalled in ...

Agency says effective HIV prevention, treatment not reaching those who could most benefit

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in Children

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in ...

All children with sustained unresponsiveness ingested concentrated and baked egg

Prenatal Vitamin Intake in Early Pregnancy May Cut Autism Risk

Prenatal Vitamin Intake in Early Pregnancy May Cut ...

ASD risk down for children whose mothers took prenatal vitamins during first month of pregnancy

is free, fast, and customized just for you!




Already a member?

Sign In Now »