Review: Venlafaxine May Be Effective for Fibromyalgia Tx

This article originally appeared here.
Share this content:
Review: Venlafaxine May Be Effective for Fibromyalgia Tx
Review: Venlafaxine May Be Effective for Fibromyalgia Tx

FRIDAY, Jan. 16, 2015 (HealthDay News) -- Venlafaxine seems to be effective for the treatment of fibromyalgia, although studies are limited by small sample size and methodological concerns, according to a review published in the February issue of the Journal of Clinical Pharmacy and Therapeutics.

Luke A. VanderWeide, Pharm.D., from the University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences in Aurora, and colleagues conducted a systematic review of venlafaxine for the treatment of fibromyalgia. The authors included data from five clinical studies (four open-label cohort studies and one randomized controlled trial) that investigated venlafaxine for the treatment of fibromyalgia. They then graded the studies according to the strength of evidence.

The researchers found that four of the published studies reported improvement in at least one outcome. There were generally consistent improvements in outcome measures related to pain, including the Fibromyalgia Impact Questionnaire, Visual Analog Scale, McGill Pain Questionnaire, and Clinical Global Impression scale. The studies were limited by small sample size, inconsistency of outcomes, and methodological concerns.

"Studies assessing the efficacy of venlafaxine in the treatment of fibromyalgia to date have been limited by small sample size, inconsistent venlafaxine dosing, lack of placebo control, and lack of blinding," the authors write. "In the context of these limitations, venlafaxine appears to be at least modestly effective in treating fibromyalgia."

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Actigraphy May Overestimate Sleep in ICU Setting

Actigraphy May Overestimate Sleep in ICU Setting

Wide ranges of sleep quality and quantity with use of actigraphy among critically ill patients in ICU

Mortality for Unintentional Drug Poisonings Up Since 1979

Mortality for Unintentional Drug Poisonings Up Since 1979

Trajectory of overall mortality rate smooth; no exponential trajectories in rates for individual drugs

Most Breast Cancer Diagnoses Given Over the Phone

Most Breast Cancer Diagnoses Given Over the Phone

This represents a reversal, with in-person diagnoses more common before 2006

is free, fast, and customized just for you!




Already a member?

Sign In Now »