Review Links Sleep-Disordered Breathing, Cognitive Impairment

Share this content:
Review Links Sleep-Disordered Breathing, Cognitive Impairment
Review Links Sleep-Disordered Breathing, Cognitive Impairment

WEDNESDAY, Aug. 30, 2017 (HealthDay News) -- Sleep-disordered breathing (SDB) is associated with increased likelihood of cognitive impairment, according to a review published online Aug. 28 in JAMA Neurology.

Yue Leng, Ph.D., from the University of California in San Francisco, and colleagues examined the correlation between SDB and risk of cognitive impairment in a systematic review. Data were included from cross-sectional and prospective studies with at least 200 participants (mean age, 40 years or older). Fourteen studies were included, of which six were prospective. The studies covered 4,288,419 men and women.

The researchers found that in pooled analysis of the six prospective studies, those with SDB were more likely to develop cognitive impairment (risk ratio, 1.26; 95 percent confidence interval, 1.05 to 1.5), with no indication of publication bias but significant heterogeneity between studies. The pooled risk ratio was 1.35 (95 percent confidence interval, 1.11 to 1.65) after the researchers removed one study that introduced significant heterogeneity. In pooled analysis of the seven cross-sectional studies, those with SBD had worse executive function (standard mean difference, −0.05; 95 percent confidence interval, −0.09 to 0), with no indication of heterogeneity or publication bias. There was no correlation between SDB and global cognition or memory.

"Further studies are required to determine the mechanisms linking these common conditions and whether treatment of SDB might reduce risk of cognitive impairment," the authors write.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Ground Beef Recalled After E. Coli Outbreak

Ground Beef Recalled After <i>E. Coli</i> Outbreak

Beef was produced and packaged at Cargill Meat Solutions in Fort Morgan, Colo.

Prevalence of Alzheimer's, Related Dementia Set to Double

Prevalence of Alzheimer's, Related Dementia Set to Double

Alzheimer's disease and related dementias burden is expected to increase to 3.3 percent in 2060

Long-Term Outcomes of Breast Implants Explored

Long-Term Outcomes of Breast Implants Explored

Higher rates of Sjogren syndrome, scleroderma, RA, stillbirth, melanoma for silicone implants

is free, fast, and customized just for you!




Already a member?

Sign In Now »