Regional Anesthesia Tied to Lower Opioid Use in TKA, THA

Share this content:
Regional Anesthesia Tied to Lower Opioid Use in TKA, THA
Regional Anesthesia Tied to Lower Opioid Use in TKA, THA

THURSDAY, May 24, 2018 (HealthDay News) -- Regional anesthesia is associated with a lower opioid consumption in both knee and hip replacement surgeries, compared to general anesthesia, according to a study published May 14 in PAIN Practice.

Katharina Donauer, M.D., from Saarland University in Homburg, Germany, and colleagues used the international PAIN OUT registry (2010 to 2016) to identify 2,346 cases of knee arthroplasty and 2,315 of hip arthroplasty. The authors sought to compare morphine consumption on the first postoperative day based upon the use of regional anesthesia versus general anesthesia.

The researchers found that for knee surgery, regional anesthesia was associated with reduced opioid consumption (P < 0.001) and less pain (P = 0.001) than general anesthesia, after adjustments for confounders. In hip surgery, regional anesthesia was only associated with reduced opioid consumption (P < 0.001), not less pain (P = 0.1).

"All cohorts with regional anesthesia showed a reduced opioid consumption not leading to reduced odds for nausea compared to systemic analgesia," the authors write.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: Progress in HIV Prevention Has Stalled in the United States

CDC: Progress in HIV Prevention Has Stalled in ...

Agency says effective HIV prevention, treatment not reaching those who could most benefit

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in Children

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in ...

All children with sustained unresponsiveness ingested concentrated and baked egg

Prenatal Vitamin Intake in Early Pregnancy May Cut Autism Risk

Prenatal Vitamin Intake in Early Pregnancy May Cut ...

ASD risk down for children whose mothers took prenatal vitamins during first month of pregnancy

is free, fast, and customized just for you!




Already a member?

Sign In Now »