Progression of Obesity Influences Risk of Diabetes Over Life Course

Share this content:
Progression of Obesity Influences Risk of Diabetes Over Life Course
Progression of Obesity Influences Risk of Diabetes Over Life Course

THURSDAY, March 8, 2018 (HealthDay News) -- Changes in weight influence the risk of diabetes, with lower risk of diabetes for obese individuals who lose weight versus stable obesity, according to a study published online March 5 in Diabetes Care.

Andrew Stokes, Ph.D., from the Boston University School of Public Health, and colleagues categorized individuals into four weight-change groups from young adulthood to midlife: stable non-obese, losing (moved from obese to non-obese), gaining (moved from non-obese to obese), and stable obese. Weight change was related to incident diabetes over 10 years of follow-up.

The researchers found that, compared to those with stable obesity, those who were obese and lost weight had a significantly lower risk of diabetes (hazard ratio [HR], 0.33). Lower risk was also seen for those who were stable non-obese (HR, 0.22) and those in the gaining category (HR, 0.70). Compared with individuals who were stable non-obese, there was evidence of an increased incidence of diabetes among obese individuals who lost weight; weight loss was rare and the correlation was not statistically significant. During the 10-year period, an estimated 9.1 percent of observed diabetes cases could have been averted if those who were obese had become non-obese; 64.2 percent of cases could have been averted if the population had maintained a normal body mass index.

"The findings from this study underscore the importance of population-level approaches to the prevention and treatment of obesity across the life course of individualS," the authors write.

Several authors disclosed financial ties to Johnson & Johnson and Ethicon (a Johnson & Johnson Company), which partially funded the study.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: Increase Seen in Salmonella Illnesses From Ground Beef

CDC: Increase Seen in <i>Salmonella</i> Illnesses From Ground ...

246 people now sickened; 59 people have been hospitalized; no deaths reported to date

Epinephrine Personal Autoinjectors Cost-Effective at 24

Epinephrine Personal Autoinjectors Cost-Effective at &#36;24

Based on 10-fold fatality risk difference, value-based price for personal epinephrine $24

Burden of Liver Cancer Rising in Medicare Patients

Burden of Liver Cancer Rising in Medicare Patients

Coexistence of other liver conditions tied to even higher risk for death, health care costs

is free, fast, and customized just for you!




Already a member?

Sign In Now »