Prenatal n-3 LCPUFAs Don't Cut IgE-Linked Disease in Children

Share this content:
Prenatal n-3 LCPUFAs Don't Cut IgE-Linked Disease in Children
Prenatal n-3 LCPUFAs Don't Cut IgE-Linked Disease in Children

THURSDAY, May 26, 2016 (HealthDay News) -- Prenatal supplementation with omega-3 (n-3) long-chain polyunsaturated fatty acids (LCPUFA) does not reduce immunoglobulin E (IgE)-associated allergic disease in children, according to a study published online May 25 in Pediatrics.

Karen P. Best, R.N., Ph.D., from the South Australian Health and Medical Research Institute in Adelaide, and colleagues assessed 706 children with a family history of allergic disease from the Docosahexaenoic Acid to Optimize Mother Infant Outcome trial at six-year follow-up. Women enrolled in the trial were randomized to n-3 LCPUFA-rich fish oil capsules or vegetable oil capsules.

The researchers found that the percentage of children with any IgE-associated allergic disease did not differ between the n-3 LCPUFA and control groups (31.5 versus 31.5 percent; adjusted relative risk, 1.04; 95 percent confidence interval, 0.82 to 1.33). The percentage of children sensitized to house dust mite Dermatophagoides farinae was reduced in the n-3 LCPUFA group (13.4 versus 20.3 percent; adjusted relative risk, 0.67; 95 percent confidence interval, 0.44 to 1.00).

"Prenatal n-3 LCPUFA supplementation did not reduce IgE-associated allergic disease at 6 years of age," the authors write. "Secondary outcomes were suggestive of a protective effect of the intervention on the incidence of D. farinae sensitization."

Two authors disclosed financial ties to the nutrition industry; one author has a patent pending.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Critics Demand Stop to 'Guinea Pig' Sepsis Clinical Trial

Critics Demand Stop to 'Guinea Pig' Sepsis Clinical ...

Clovers trial seeks to determine which IV fluids, vasopressors combo works best to curb sepsis

Education Can Up Emotional Intelligence in Residents

Education Can Up Emotional Intelligence in Residents

Increase in total EI median scores, stress management composite score after intervention

Cancer-Related Gene Variations Frequently Reclassified

Cancer-Related Gene Variations Frequently Reclassified

24.9 percent of variants of uncertain significance were reclassified at a single commercial laboratory

is free, fast, and customized just for you!




Already a member?

Sign In Now »