Pre-, Post-Op C-Reactive Protein Levels Tied to Delirium

This article originally appeared here.
Share this content:
Pre-, Post-Op C-Reactive Protein Levels Tied to Delirium
Pre-, Post-Op C-Reactive Protein Levels Tied to Delirium

WEDNESDAY, July 5, 2017 (HealthDay News) -- For older adults undergoing major noncardiac surgery, preoperative and postoperative day 2 (POD2) C-reactive protein (CRP) levels are associated with the incidence, duration, and severity of delirium, according to a study published online May 26 in the Journal of the American Geriatrics Society.

Sarinnapha M. Vasunilashorn, Ph.D., from the Beth Israel Deaconess Medical Center in Boston, and colleagues conducted a prospective cohort study involving 560 adults aged 70 years and older undergoing major noncardiac surgery. They examined the correlation between CRP measured preoperatively and on POD2 and the incidence, duration, and feature severity of delirium.

The researchers found that postoperative delirium occurred in 24 percent of participants and that 12 percent had two or more delirium days. Compared with those with a preoperative CRP <3 mg/L, participants with preoperative CRP ≥3 mg/L had a 1.5-fold increased risk of delirium, 0.4 more delirium days, more severe delirium, and a 1.4-fold risk of prolonged length of stay after adjustment for age, sex, surgery type, anesthesia route, medical comorbidities, and postoperative infectious complications. Participants in the highest quartile of CRP POD2 were 1.5-fold more likely to develop delirium, had 0.2 more delirium days, and had more severe delirium compared with those in the lowest quartile.

"CRP may be useful to identify individuals who are at risk of developing delirium," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Gender Nonconformity Linked to Students' Mental Distress

Gender Nonconformity Linked to Students' Mental Distress

For male students, gender nonconformity strongly associated with substance use

Participation Up With Online Diabetes Prevention Program

Participation Up With Online Diabetes Prevention Program

But weight loss no different for online, in-person DPP for obese/overweight veterans with prediabetes

Net Benefit of Anticoagulants for A-Fib Varies With Stroke Rate

Net Benefit of Anticoagulants for A-Fib Varies With ...

Benefit of warfarin anticoagulation varies with varying published stroke rates

is free, fast, and customized just for you!




Already a member?

Sign In Now »