Pre-Op Opioid Use Tied to Higher Post-Op Dependence

Share this content:
Pre-Op Opioid Use Tied to Higher Post-Op Dependence
Pre-Op Opioid Use Tied to Higher Post-Op Dependence

(HealthDay News) -- Greater preoperative opioid use predicts increased immediate postoperative opioid demand and decreased incidence of postoperative opioid independence among spine surgery patients, according to a study published in the Dec. 1 issue of Spine.

Sheyan J. Armaghani, M.D., from the Vanderbilt University School of Medicine in Nashville, Tenn., and colleagues assessed self-reported daily opioid consumption preoperatively (converted into morphine equivalent amounts) and at the 12-month postoperative point in 583 patients undergoing spine surgery.

The researchers found that the median preoperative morphine equivalent amount for the group was 8.75 mg. More than half of patients (55 percent) reported some degree of opioid use. Increased intraoperative opioid demand was significantly associated with younger age, more invasive surgery, anxiety, and primary surgery (P < 0.05). Similarly, younger age, anxiety, and greater preoperative opioid use were significantly associated with increased immediate postoperative opioid demand (P < 0.05). There was a significant decreased incidence of opioid independence 12 months postoperatively with more invasive surgery, anxiety, revision surgery, and greater preoperative opioid use (P < 0.01).

"Patients may benefit from preoperative counseling that emphasizes minimizing opioid use prior to undergoing spine surgery," the authors write.

Relevant financial activities outside the submitted work were disclosed: consultancy, grants.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Permits Marketing of Brain Stimulation Device for OCD

FDA Permits Marketing of Brain Stimulation Device for ...

FDA previously approved transcranial magnetic stimulation for major depression, certain migraines

Comments Open on End of NIH Review for Gene Therapy Studies

Comments Open on End of NIH Review for ...

NIH oversight panel no longer plans to review all applications for gene therapy experiments

U.S. Measles Outbreak Hits 107 Cases in 21 States, D.C.

U.S. Measles Outbreak Hits 107 Cases in 21 ...

Outbreak on track to exceed last year's; most of the people who got measles weren't vaccinated

is free, fast, and customized just for you!




Already a member?

Sign In Now »