Peri-Op RBC Transfusions Linked to Postoperative VTE

Share this content:
Peri-Op RBC Transfusions Linked to Postoperative VTE
Peri-Op RBC Transfusions Linked to Postoperative VTE

THURSDAY, June 14, 2018 (HealthDay News) -- Perioperative red blood cell (RBC) transfusions are associated with the development of new or progressive postoperative venous thromboembolism (VTE), according to a study published online June 13 in JAMA Surgery.

Ruchika Goel, M.D., M.P.H., from New York Presbyterian Hospital in New York City, and colleagues used prospectively collected registry data from the American College of Surgery National Surgical Quality Improvement Program (ACS-NSQIP) database to examine the correlation between perioperative RBC transfusions and postoperative VTE within 30 days of surgery. A total of 750,937 patients in the ACS-NSQIP registry who underwent a surgical procedure were included in the analysis.

The researchers found that 6.3 percent of the patients received at least one perioperative RBC transfusion. Overall, 0.8 percent of patients had postoperative VTE. Perioperative RBC transfusion was correlated with increased odds of VTE, deep vein thrombosis, and pulmonary embolism (adjusted odds ratios, 2.1, 2.2, and 1.9, respectively), independent of various possible risk factors. As the number of intraoperative and/or postoperative RBC transfusion events increased, there was a significant dose-response effect (adjusted odds ratios, 2.1, 3.1, and 4.5 for one, two, and three or more events, respectively, versus no intraoperative or postoperative transfusions). Across all surgical subspecialties analyzed, the correlation between any perioperative RBC transfusion and postoperative VTE remained statistically significant.

"These findings, if validated, should reinforce the importance of rigorous perioperative management of blood transfusion practices," the authors write.

Abstract/Full Text

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: More Than 400 Sickened by McDonald's Salads

CDC: More Than 400 Sickened by McDonald's Salads

Multistate outbreak of Cyclosporiasis linked to McDonald's Fresh Express Salad Mix

Jury Awards 289 Million in Case Linking Roundup to Man's Cancer

Jury Awards $289 Million in Case Linking Roundup ...

Case could set a precedent for other lawsuits against Monsanto, the manufacturer of Roundup

Prenatal Tdap Vaccination Not Linked to Autism Risk

Prenatal Tdap Vaccination Not Linked to Autism Risk

No increased risk of autism spectrum disorder in association with prenatal Tdap vaccination

is free, fast, and customized just for you!




Already a member?

Sign In Now »