Patient-Controlled Anesthesia Non-Inferior After C-Section

This article originally appeared here.
Share this content:
Patient-Controlled Anesthesia Non-Inferior After C-Section
Patient-Controlled Anesthesia Non-Inferior After C-Section

WEDNESDAY, March 16, 2016 (HealthDay News) -- Early patient-controlled oral analgesia is non-inferior to standard parenteral analgesia for pain management after elective cesarean section, according to a study published online March 2 in Anaesthesia.

Aurélien Bonnal, M.D., from the Arnaud de Villeneuve University Hospital in Montpellier, France, and colleagues compared the effectiveness of early patient-controlled oral analgesia versus parenteral analgesia in 77 women undergoing elective cesarean section under regional anesthesia. Participants received analgesia with acetaminophen, ketoprofen, and morphine. Those with patient-controlled oral analgesia were given four pillboxes containing tablets and instructions for self-medication on the postnatal ward.

The researchers found that in the patient-controlled oral analgesia group, the one sided 95 percent confidence interval of the difference in mean pain scores was significantly lower than 1 at all time points at rest and on movement, meeting the criteria for non-inferiority. More women in the patient-controlled oral analgesia group used morphine (58 versus 23 percent; P = 0.002); the median number of morphine doses was two in the patient-controlled group, versus one in the parenteral group (P = 0.006). Thirteen percent of women receiving patient-controlled oral analgesia had minor drug errors or omissions. The patient-controlled analgesia group more frequently had pruritus (37 versus 15 percent; P = 0.03).

"After elective cesarean section, early patient-controlled oral analgesia is non-inferior to standard parenteral analgesia for pain management, and can be one of the steps of an enhanced recovery process," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Permits Marketing of Brain Stimulation Device for OCD

FDA Permits Marketing of Brain Stimulation Device for ...

FDA previously approved transcranial magnetic stimulation for major depression, certain migraines

Comments Open on End of NIH Review for Gene Therapy Studies

Comments Open on End of NIH Review for ...

NIH oversight panel no longer plans to review all applications for gene therapy experiments

U.S. Measles Outbreak Hits 107 Cases in 21 States, D.C.

U.S. Measles Outbreak Hits 107 Cases in 21 ...

Outbreak on track to exceed last year's; most of the people who got measles weren't vaccinated

is free, fast, and customized just for you!




Already a member?

Sign In Now »