Oncocytomas Tend to Grow Slowly Over Time

This article originally appeared here.
Share this content:
Oncocytomas Tend to Grow Slowly Over Time
Oncocytomas Tend to Grow Slowly Over Time

THURSDAY, Feb. 18, 2016 (HealthDay News) -- The majority of oncocytic renal neoplasms will grow with time, according to a study published in the March issue of The Journal of Urology.

Patrick O. Richard, M.D., from the Princess Margaret Cancer Center in Toronto, and colleagues conducted a single center, retrospective study of patients diagnosed with lesions suggestive of oncocytoma or chromophobe renal cell carcinoma between 2003 and 2014. A mixed effect linear model was used to estimate growth rates.

The researchers found that 98 percent of the 95 lesions (81 oncocytoma, 14 chromophobe renal cell carcinoma) included in the analysis were diagnosed on biopsy. During a median follow-up of 34 and 25 months, respectively, the annual growth rate was 0.14 cm for oncocytoma and 0.38 cm for chromophobe renal cell carcinoma. There was a significant correlation for baseline lesion size with growth (P < 0.001). Growth was detected in 74 percent of oncocytomas and 67 percent of chromophobe renal cell carcinomas followed up to the three-year mark. Of these, eight patients underwent surgery (six in the chromophobe renal cell carcinoma group). In all patients the initial diagnosis was confirmed. Five patients died, all of nonrenal-related causes.

"Our experience indicates that oncocytomas and to some extent chromophobe renal cell carcinoma can initially be safely observed with regular imaging," the authors write. "Patients should be reassured that growth is not necessarily a sign of malignancy as most lesions will grow slowly with time."

One author disclosed financial ties to Omnyx Digital Pathology.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Permits Marketing of Brain Stimulation Device for OCD

FDA Permits Marketing of Brain Stimulation Device for ...

FDA previously approved transcranial magnetic stimulation for major depression, certain migraines

Comments Open on End of NIH Review for Gene Therapy Studies

Comments Open on End of NIH Review for ...

NIH oversight panel no longer plans to review all applications for gene therapy experiments

U.S. Measles Outbreak Hits 107 Cases in 21 States, D.C.

U.S. Measles Outbreak Hits 107 Cases in 21 ...

Outbreak on track to exceed last year's; most of the people who got measles weren't vaccinated

is free, fast, and customized just for you!




Already a member?

Sign In Now »