Obstructive Sleep Apnea Linked to Thinning of Calvaria, Skull Base

Share this content:
Obstructive Sleep Apnea Linked to Thinning of Calvaria, Skull Base
Obstructive Sleep Apnea Linked to Thinning of Calvaria, Skull Base

FRIDAY, May 4, 2018 (HealthDay News) -- Obstructive sleep apnea (OSA) is associated with thinning of the calvaria and skull base, according to a study published online May 3 in JAMA Otolaryngology-Head & Neck Surgery.

Cyrus Rabbani, M.D., from Indiana University School of Medicine in Indianapolis, and colleagues conducted a retrospective cohort study of 1,012 patients who underwent a polysomnogram and had high-resolution computed tomographic imaging of the head. Patients with and without OSA (56 and 58 patients, respectively) were matched for age and body mass index.

The researchers found that patients with OSA had thinner mean calvaria (2.73 versus 2.47 mm; difference, −0.26 mm [95 percent confidence interval, −0.49 to −0.04]) and thinner skull bases (5.03 versus 4.32 mm; difference, −0.71 mm [95 percent confidence interval, −1.23 to −0.19]). The mean extracranial zygoma thickness was the same for those with and without OSA (4.92 versus 4.84 mm; difference, −0.07 mm; 95 percent confidence interval, −0.39 to 0.24). In nearly twice as many patients with versus without OSA, the tegmen mastoideum was dehiscent (37 versus 20 percent; difference, 17 percent; 95 percent confidence interval, 0.4 to 32).

"OSA was independently associated with intracranial bone (calvaria and skull base) thinning and not with extracranial (zygoma) thinning," the authors write. "These findings support a possible role of OSA in the pathophysiologic development of spontaneous cerebrospinal fluid leaks."

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Zika, West Nile Cases Reported in Alabama

Zika, West Nile Cases Reported in Alabama

State health officials note that Zika hasn't been transmitted locally

TBI Linked to Increased Suicide Risk

TBI Linked to Increased Suicide Risk

Increased suicide risk with one, two, and three or more medical contacts for traumatic brain injury

Triple Combo Blood Pressure Pill Can Improve BP Control

Triple Combo Blood Pressure Pill Can Improve BP ...

Proportion achieving target BP increased with use of triple combo pill versus usual care at six months

is free, fast, and customized just for you!




Already a member?

Sign In Now »