Nutraceuticals Alone or With Ezetimibe Aid in Dyslipidemia

This article originally appeared here.
Share this content:
Nutraceuticals Alone or With Ezetimibe Aid in Dyslipidemia
Nutraceuticals Alone or With Ezetimibe Aid in Dyslipidemia

THURSDAY, Dec. 10, 2015 (HealthDay News) -- For statin-intolerant patients with dyslipidemia with ischemic heart disease treated with percutaneous coronary intervention, nutraceuticals alone or in combination with ezetimibe improve the lipid profile, according to a study published in the Dec. 15 issue of The American Journal of Cardiology.

Giuseppe Marazzi, M.D., Ph.D., from the Istituto di Ricerca a Carattere Scientifico San Raffaele Pisana in Rome, and colleagues conducted a randomized, prospective study comparing the safety and efficacy of a combination of nutraceuticals (red yeast rice, policosanol, berberine, folic acid, coenzyme Q10, and astaxanthin) and ezetimibe for three months. Patients who did not achieve their therapeutic target could add the alternative treatment for an additional 12 months. The authors enrolled 100 patients who were dyslipidemic with ischemic heart disease treated with percutaneous coronary intervention (50 to nutraceuticals and 50 to ezetimibe).

The researchers found that 14 patients in the nutraceutical group and none in the ezetimibe group achieved their therapeutic target (low-density lipoprotein cholesterol <100 mg/dL) after three months. The therapeutic goal was reached by 72.8 percent of the combined therapy group and by 100 percent of the nutraceutical group at one-year follow-up. There were no reports of important undesirable effects.

"Nutraceuticals alone or in combination with ezetimibe are well tolerated and improve the lipid profile in statin-intolerant patients with coronary heart disease," the authors write. "Further studies are needed to assess long-term effects of nutraceuticals on mortality."

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Dermatologists' Rx for Antibiotics Dropped From 2008 to 2016

Dermatologists' Rx for Antibiotics Dropped From 2008 to ...

However, rising use of antibiotics after dermatologic surgical visits is concerning

Coronary Artery Calcium May Help Predict CVD in South Asians

Coronary Artery Calcium May Help Predict CVD in ...

CAC incidence similar in South Asian men versus white, black, Latino men; higher than Chinese

High Levels of Activity, Motor Ability Linked to Better Cognition

High Levels of Activity, Motor Ability Linked to ...

Findings seen in older adults; independent correlations remained for those with Alzheimer disease

is free, fast, and customized just for you!




Already a member?

Sign In Now »