November 2018 Briefing - Diabetes & Endocrinology

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for November 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Family Functioning Does Not Impact Family Dinner, Diet Link

FRIDAY, Nov. 30, 2018 (HealthDay News) -- Among adolescents and young adults, family dinner frequency is associated with healthful dietary intake, regardless of family functioning, according to a study published online Nov. 21 in JAMA Network Open.

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Rotating Night Shift Work, Lifestyle Factors Linked to T2DM

FRIDAY, Nov. 30, 2018 (HealthDay News) -- Both rotating night shift work and unhealthy lifestyle are associated with an increased risk for type 2 diabetes among female nurses, with a significant additive interaction, according to a study published online Nov. 21 in the BMJ.

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Higher Cardiovascular Risk Seen With Psoriatic Arthritis

FRIDAY, Nov. 30, 2018 (HealthDay News) -- Cardiovascular risk should be carefully evaluated in patients with psoriatic arthritis, according to a study published online Nov. 5 in the International Journal of Rheumatic Diseases.

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Care for Chronic Kidney Disease Varies Across VA Facilities

FRIDAY, Nov. 30, 2018 (HealthDay News) -- For veterans with diabetes and concomitant chronic kidney disease (CKD), CKD care, including ordering laboratory tests and scheduling nephrology referrals, varies considerably by facility, according to a study published online Nov. 29 in the Clinical Journal of the American Society of Nephrology.

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Several Risk Factors More Strongly Linked to MI in Women

FRIDAY, Nov. 30, 2018 (HealthDay News) -- The incidence of myocardial infarction (MI) is higher in men than women, but several risk factors are more strongly linked to MI in women, according to a study published online Nov. 7 in The BMJ.

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Bone Indices on CT Scan Predict Fracture Risk in Older Adults

FRIDAY, Nov. 30, 2018 (HealthDay News) -- High-resolution peripheral quantitative computed tomography (HR-pQCT) indices improve prediction of fracture beyond bone mineral density and Fracture Risk Assessment Tool (FRAX) scores in older adults, according to a study published online Nov. 28 in The Lancet Diabetes & Endocrinology.

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Certain SGLT2 Inhibitors, GLP-1 RAs for T2DM Also Cut CV Risk

THURSDAY, Nov. 29, 2018 (HealthDay News) -- Certain sodium-glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide 1 receptor agonists (GLP-1 RAs) demonstrate significant cardiovascular (CV) benefit and should be used for reducing CV risk in patients with type 2 diabetes (T2D) and atherosclerotic cardiovascular disease (ASCVD), according to a report of the American College of Cardiology Task Force on Expert Consensus Decision Pathways published online Nov. 26 in the Journal of the American College of Cardiology.

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Large at Birth, Maternal Diabetes Up Child's Risk for Obesity

WEDNESDAY, Nov. 28, 2018 (HealthDay News) -- Large for gestational age (LGA) is a stronger marker than maternal diabetes for subsequently being overweight or obese in early childhood, according to a study published online Nov. 13 in Diabetologia.

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FDA to Update Medical Device Approvals Process

TUESDAY, Nov. 27, 2018 (HealthDay News) -- A major update of the United States' system for approving medical devices was announced yesterday by the Food and Drug Administration.

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Four Principles Underlie Patient and Family Partnership in Care

TUESDAY, Nov. 27, 2018 (HealthDay News) -- Patient and family partnership in care should include treatment of patients and families with dignity and respect, their active engagement in all aspects of care, and their contribution to the improvement of health care systems and education of health care professionals, according to a position paper published online Nov. 27 in the Annals of Internal Medicine.

Position Paper
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Food Assistance May Help Older Adults Adhere to Diabetes Meds

TUESDAY, Nov. 27, 2018 (HealthDay News) -- Participation in the Supplemental Nutrition Assistance Program (SNAP) may reduce the number of low-income older adults with diabetes forgoing medications because of cost, according to a study published online Nov. 19 in JAMA Internal Medicine.

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ACA Coverage Substantial, but Did Not Impact Labor Markets

MONDAY, Nov. 26, 2018 (HealthDay News) -- Millions of workers gained insurance coverage under the Affordable Care Act (ACA) without adverse effects on labor markets, according to a report published by the Robert Wood Johnson Foundation and the Urban Institute.

Report: How Have Workers Fared Under the ACA?

Insulin Needed for T2DM Tx Set to Increase >20 Percent by 2030

MONDAY, Nov. 26, 2018 (HealthDay News) -- From 2018 to 2030, the insulin required to treat type 2 diabetes is expected to increase more than 20 percent, according to a study published online Nov. 20 in The Lancet Diabetes & Endocrinology.

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Switching to High-Deductible Insurance Delays Diabetes Care

WEDNESDAY, Nov. 21, 2018 (HealthDay News) -- For patients with diabetes, those switching from low-deductible to high-deductible insurance have increased delays in seeking care and diagnostic testing for macrovascular symptoms and for first procedure-based treatment, according to a study published online Nov. 20 in the Annals of Internal Medicine.

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NPs and PAs Can Effectively Manage Diabetes in Primary Care

TUESDAY, Nov. 20, 2018 (HealthDay News) -- Diabetes outcomes do not differ for patients treated with a primary care provider who is either a physician, nurse practitioner (NP), or physician assistant (PA), according to a study published online Nov. 20 in the Annals of Internal Medicine.

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Higher Risk for Amputation, DKA With SGLT2 Inhibitors for T2DM

FRIDAY, Nov. 16, 2018 (HealthDay News) -- Use of sodium glucose cotransporter 2 (SGLT2) inhibitors is associated with an increased risk for lower-limb amputation and diabetic ketoacidosis compared with use of glucagon-like peptide 1 (GLP1) receptor agonists, according to a study published online Nov. 14 in The BMJ.

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CDC: 8.8 Percent Uninsured in U.S. in First Half of 2018

FRIDAY, Nov. 16, 2018 (HealthDay News) -- In the first six months of 2018, 8.8 percent of U.S. individuals of all ages were uninsured, which was not significantly different from 2017, according to a report published Nov. 15 by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Name-Brand Medications Driving Spike in U.S. Drug Spending

THURSDAY, Nov. 15, 2018 (HealthDay News) -- Rising drug spending in the United States is being fueled by expensive name-brand prescription medicines, a new study shows.

NBC News Article
Blue Cross Blue Shield Report

CDC: Many Americans May Have Prediabetes and Not Know It

THURSDAY, Nov. 15, 2018 (HealthDay News) -- More than one-third of Americans have prediabetes, but 90 percent of them do not know they have it, medical experts say.

Do I Have Prediabetes
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Patient Experiences Shed Light on Diagnostic Errors

THURSDAY, Nov. 15, 2018 (HealthDay News) -- Data from patient- and family-reported error narratives indicate that problems related to patient-physician interactions are major contributors to diagnostic errors, according to a study published in the November issue of Health Affairs.

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AMA to Collect Data on Suicide Among Doctors-in-Training

WEDNESDAY, Nov. 14, 2018 (HealthDay News) -- By collecting data on suicides by medical students, residents, and fellows, the American Medical Association hopes to identify ways to reduce suicides among doctors-in-training. The data collection policy was approved at a meeting yesterday.

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Changes in Risk Indicators of MetS Severity Tied to T2DM Risk

WEDNESDAY, Nov. 14, 2018 (HealthDay News) -- For patients with prediabetes who are randomly assigned to interventions, changes in risk indicators of metabolic syndrome (MetS) severity are associated with the risk for type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD), according to a study published in the November issue of Diabetes Care.

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Denosumab Promising for TDT-Induced Osteoporosis Treatment

TUESDAY, Nov. 13, 2018 (HealthDay News) -- Denosumab (DNM), a fully human monoclonal antibody against the receptor activator of nuclear factor kappa-B ligand (RANKL), may be beneficial for managing transfusion-dependent thalassemia (TDT)-induced osteoporosis, according to a study published online Oct. 31 in Blood Advances.

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Progress Toward Goals in Global Health Is Slowing

FRIDAY, Nov. 9, 2018 (HealthDay News) -- Global progress in health has slowed, and improvements in health have been unevenly distributed, according to a series of articles published in a special issue of The Lancet, highlighting the fact that global progress in health is not inevitable.

The Lancet - The Global Burden of Disease Study 2017

Genetic Test Helps ID Benign Versus Malignant Thyroid Nodules

FRIDAY, Nov. 9, 2018 (HealthDay News) -- A multigene genomic classifier (GC) test for thyroid nodules with indeterminate cytology shows high sensitivity and negative predictive value, according to a study published online Nov. 8 in JAMA Oncology.

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CDC: About One in Three Adults With Prediabetes Has Arthritis

FRIDAY, Nov. 9, 2018 (HealthDay News) -- About one in three adults with prediabetes has arthritis, and half of those with both conditions are physically inactive and/or obese, according to research published in the Nov. 9 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Medicaid Expansion Approved in Three Republican-Leaning States

WEDNESDAY, Nov. 7, 2018 (HealthDay News) -- Hundreds of thousands more low-income Americans could get health insurance after voters in three Republican-leaning states approved Medicaid expansion in the midterm elections.

CNBC Article

Excess Gestational Weight Gain Not Better for Child Bone Health

WEDNESDAY, Nov. 7, 2018 (HealthDay News) -- Among women who are under/normal weight, gestational weight gain (GWG) is associated with slightly increased bone measures in offspring at age 7 years, but there is no effect for overweight/obese mothers, according to a study published online Nov. 7 in the Journal of Bone and Mineral Research.

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Colectomy Appears to Increase Later Risk of Type 2 Diabetes

WEDNESDAY, Nov. 7, 2018 (HealthDay News) -- Patients who have the entire or left side of the colon removed show increased risk for developing type 2 diabetes in the 18 years following surgery, according to a study published online Oct. 30 in eLife.

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Majority of Internists Still Have Financial Ties to Industry

MONDAY, Nov. 5, 2018 (HealthDay News) -- A majority of internists still report financial ties to industry, according to a study published online Oct. 5 in the Journal of General Internal Medicine.

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Abnormalities in Genes Linked to IRSP in Alzheimer's Disease

MONDAY, Nov. 5, 2018 (HealthDay News) -- Individuals with Alzheimer's disease (AD) have abnormalities and reductions in gene expression in the parahippocampal gyri that map to genes associated with the insulin receptor signaling pathway (IRSP), according to a study published online Nov. 1 in PLOS ONE.

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Older Paternal Age Linked to Adverse Perinatal Outcomes

MONDAY, Nov. 5, 2018 (HealthDay News) -- Advanced paternal age is associated with adverse infant and maternal outcomes, according to a study published online Oct. 31 in The BMJ.

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Sign-Up Season Begins on HealthCare.gov

FRIDAY, Nov. 2, 2018 (HealthDay News) -- The federal government website where Americans can sign up for health insurance under the Affordable Care Act is up and running, officials said yesterday.

AP News Article
HealthCare.gov

National Youth Obesity Rate at 15.8 Percent for 2016 to 2017

FRIDAY, Nov. 2, 2018 (HealthDay News) -- In 2016 to 2017, the national obesity rate for youth ages 10 to 17 years was 15.8 percent, which was not statistically different from the 16.1 percent rate in 2016 alone, according to a report published by the Robert Wood Johnson Foundation.

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CDC: Prevalence of Gestational Diabetes 6.0 Percent in 2016

FRIDAY, Nov. 2, 2018 (HealthDay News) -- The prevalence of gestational diabetes was 6.0 percent in 2016, with a slight increase seen from 2012 to 2016, according to research published in the Nov. 2 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Plant-Based Diets Beneficial for Adults With Type 2 Diabetes

THURSDAY, Nov. 1, 2018 (HealthDay News) -- For adults with type 2 diabetes, plant-based diets can improve psychological health, quality of life, hemoglobin A1c levels, and weight, according to a review published online Oct. 30 in BMJ Open Diabetes Research & Care.

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Financial Conflicts of Interest Prevalent Among CPG Authors

THURSDAY, Nov. 1, 2018 (HealthDay News) -- There is a high prevalence of financial conflicts of interest among authors of clinical practice guidelines (CPGs) related to high-revenue medications and in gastroenterology, according to two research letters published online Oct. 29 in JAMA Internal Medicine.

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