Novel Case of Alzheimer's Reported in HIV+ Patient

This article originally appeared here.
Share this content:
Novel Case of Alzheimer's Reported in HIV+ Patient
Novel Case of Alzheimer's Reported in HIV+ Patient

TUESDAY, April 19, 2016 (HealthDay News) -- The first case of Alzheimer's disease (AD) diagnosed in a person with HIV suggests progressive dementia in older HIV+ individuals may be due to HIV-associated neurocognitive disorder (HAND), AD, or both. The case study was published online April 14 in Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring.

The patient -- a 71-year-old man -- was diagnosed after a medical scan revealed amyloid deposition in his brain. Until now, it was believed that HIV-related inflammation in the brain might prevent the formation of such deposition and thereby protect these patients from Alzheimer's.

"HIV infection does not preclude central nervous system Aβ/amyloid deposition," the authors write. "Amyloid positron emission tomography imaging may be of value in distinguishing HAND from AD pathologies."

"This patient may be a sentinel case that disputes what we thought we knew about dementia in HIV-positive individuals," study author R. Scott Turner, M.D., of the Memory Disorders Program at Georgetown University Medical Center in Washington, D.C., said in a university news release. The case also suggests that some older patients with HIV and dementia may be misdiagnosed with HIV-associated brain disorders, but actually have Alzheimer's disease. It's also possible that some older patients with HIV have both HIV-associated brain disorders and Alzheimer's, according to Turner.

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

NIH Panel Will No Longer Review Gene Therapy Experiments

NIH Panel Will No Longer Review Gene Therapy ...

FDA will now assess gene therapy experiments and products as it does with other treatments, drugs

is free, fast, and customized just for you!




Already a member?

Sign In Now »