Multimodal Analgesia Cuts Complications Post Arthroplasty

Share this content:
Multimodal Analgesia Cuts Complications Post Arthroplasty
Multimodal Analgesia Cuts Complications Post Arthroplasty

WEDNESDAY, March 7, 2018 (HealthDay News) -- Use of multimodal analgesia is associated with fewer complications, reduced opioid prescriptions, and reduced hospital length of stay after total hip/knee arthroplasty, according to a study published online March 1 in Anesthesiology.

Stavros G. Memtsoudis, M.D., Ph.D., from the Weill Cornell Medical College in New York City, and colleagues included data from 512,393 total hip arthroplasties and 1,028,069 total knee arthroplasties from the Premier Perspective database (2006 to 2016). The number and type of analgesic modes were examined, and groups were categorized as opioids only, and one, two, or more than two additional modes.

The researchers found that 85.6 percent of patients received multimodal analgesia. Additions of analgesic modes correlated with stepwise positive effects in multivariable models: Compared with the opioids only group, total hip arthroplasty patients receiving more than two modes experienced 19 percent fewer respiratory and gastrointestinal complications (odds ratios, 0.81 and 0.74, respectively). This group also showed up to an 18.5 percent reduction in opioid prescription, and a 12.1 percent decrease in length of stay (all P < 0.05). Similar patterns were seen for total knee arthroplasty. The most effective modalities used seemed to be nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors.

"While the optimal multimodal regimen is still not known, the findings encourage the combined use of multiple modalities in perioperative analgesic protocols," the authors write.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: Progress in HIV Prevention Has Stalled in the United States

CDC: Progress in HIV Prevention Has Stalled in ...

Agency says effective HIV prevention, treatment not reaching those who could most benefit

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in Children

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in ...

All children with sustained unresponsiveness ingested concentrated and baked egg

Prenatal Vitamin Intake in Early Pregnancy May Cut Autism Risk

Prenatal Vitamin Intake in Early Pregnancy May Cut ...

ASD risk down for children whose mothers took prenatal vitamins during first month of pregnancy

is free, fast, and customized just for you!




Already a member?

Sign In Now »