Models May Predict Two-Year Mortality Risk for CKD Patients

This article originally appeared here.
Share this content:
Models May Predict Two-Year Mortality Risk for CKD Patients
Models May Predict Two-Year Mortality Risk for CKD Patients

WEDNESDAY, March 25, 2015 (HealthDay News) -- Risk prediction models with 16 characteristics may predict mortality risk in older adults with chronic kidney disease (CKD). The findings were published in the March issue of the Journal of the American Geriatrics Society.

Jessica W. Weiss, M.D., from the Oregon Health & Sciences University in Portland, and colleagues retrospectively evaluated data from individuals with severe CKD (estimated glomerular filtration rate, <30 mL/min per 1.73 m²; 1,915 patients aged 65 to 79 years; 2,139 patients aged ≥80 years). All patients received care at the Kaiser Permanente Northwest health maintenance organization between 2000 and 2008.

The researchers found that the risk prediction models used 16 characteristics to identify participants with the highest risk of mortality at two years. There was within 5 percent agreement for predicted and observed risks for each quintile, with a four- to five-fold difference in two-year predicted mortality risk observed between the highest and lowest quintiles. Models performed similarly with respect to mortality prediction at six months and two years in terms of discrimination and calibration for each age group.

"When validated, these risk prediction models may be helpful in supporting discussions about prognosis and treatment decisions sensitive to prognosis in older adults with CKD in real-world clinical settings," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Permits Marketing of Brain Stimulation Device for OCD

FDA Permits Marketing of Brain Stimulation Device for ...

FDA previously approved transcranial magnetic stimulation for major depression, certain migraines

Comments Open on End of NIH Review for Gene Therapy Studies

Comments Open on End of NIH Review for ...

NIH oversight panel no longer plans to review all applications for gene therapy experiments

U.S. Measles Outbreak Hits 107 Cases in 21 States, D.C.

U.S. Measles Outbreak Hits 107 Cases in 21 ...

Outbreak on track to exceed last year's; most of the people who got measles weren't vaccinated

is free, fast, and customized just for you!




Already a member?

Sign In Now »