Metformin May Help Treatment-Associated Weight Gain in ASD

This article originally appeared here.
Share this content:
Metformin May Help Treatment-Associated Weight Gain in ASD
Metformin May Help Treatment-Associated Weight Gain in ASD

WEDNESDAY, Aug. 24, 2016 (HealthDay News) -- Metformin may be effective in decreasing weight gain associated with atypical antipsychotic use in autism spectrum disorder (ASD), according to a study published online Aug. 24 in JAMA Psychiatry.

Michael Aman, Ph.D., a retired professor of psychology at The Ohio State University in Columbus, and colleagues enrolled 60 individuals with ASD, aged 6 to 17. The patients were overweight due to the side effects of taking antipsychotic medications for irritability and agitation. For the study, participants were given either metformin or an inactive placebo for 16 weeks.

The researchers found that patients given metformin had much greater reductions in body mass index than those who took the placebo. Metformin was well tolerated overall.

"Our results showed that gastrointestinal side effects occurred for more days in the metformin group compared to placebo group, but the large majority of children taking metformin were able to maintain their treatment," Aman said in a university news release.

Abstract
Full Text
Editorial

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Bayer Stops U.S. Sale of Essure Birth Control Implant

Bayer Stops U.S. Sale of Essure Birth Control ...

Problems with device include chronic pain and perforations of the uterus and fallopian tubes

C.S. Mott Poll Addresses Child Safety at Amusement Parks

C.S. Mott Poll Addresses Child Safety at Amusement ...

2016 saw U.S. emergency departments deal with 30,000 injuries linked to amusement parks, carnivals

Greening Vacant Land Improves Neighborhood Mental Health

Greening Vacant Land Improves Neighborhood Mental Health

Cleaning up vacant lots in resource-limited urban settings can aid residents' mental health

is free, fast, and customized just for you!




Already a member?

Sign In Now »