Metabolic Response to Weight Loss Varies Greatly

This article originally appeared here.
Share this content:
Metabolic Response to Weight Loss Varies Greatly
Metabolic Response to Weight Loss Varies Greatly

TUESDAY, May 12, 2015 (HealthDay News) -- 'Thrifty' metabolism might sabotage weight loss efforts for some, according to a study published online May 11 in Diabetes.

"The results corroborate the idea that some people who are obese may have to work harder to lose weight due to metabolic differences," lead author Martin Reinhardt, M.D., from the Phoenix Epidemiology and Clinical Research Branch of the U.S. National Institute of Diabetes and Digestive and Kidney Diseases, said in an institute news release.

The small laboratory study included 12 obese men and women who underwent tests to assess their body's energy use in response to a day of fasting. This was followed by six weeks of reduced calorie intake. After accounting for factors such as age, sex, and race, the researchers found that participants who lost the least amount of weight during the six weeks of reducing calorie intake were those whose metabolism decreased the most during fasting. These people have what the researchers called a "thrifty" metabolism, as opposed to the "spendthrift" metabolism in participants who lost the most weight and whose metabolism decreased the least during fasting.

It's not known if people are born with different metabolic responses to lower calorie intake, or if they develop over time. Further research is needed to determine if these individual responses can be used to prevent weight gain, the study authors said. "What we've learned from this study may one day enable a more personalized approach to help people who are obese achieve a healthy weight," Griffin Rodgers, M.D., director of the Institute of Diabetes and Digestive and Kidney Diseases, said in the news release.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

WPSI Recommends Annual Urinary Incontinence Screening

WPSI Recommends Annual Urinary Incontinence Screening

Due to limited evidence, other experts urge caution in implementing guideline for women

Young, Growing Athletes at High Risk for ACL Injuries

Young, Growing Athletes at High Risk for ACL ...

Athletic teams should provide program that includes muscle strengthening, proper technique training

Side Effects of Biologics for Rheumatic Dz May Up Anxiety

Side Effects of Biologics for Rheumatic Dz May ...

Common patient concerns are risks of cancer and tuberculosis activation

is free, fast, and customized just for you!




Already a member?

Sign In Now »