May 2018 Briefing - Neurology

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Here are what the editors at HealthDay consider to be the most important developments in Neurology for May 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

ASHP: SVP, Injectable Opioid Shortages Threaten Patient Care

THURSDAY, May 31, 2018 (HealthDay News) -- The widespread shortages of injectable opioids and small-volume parenteral (SVP) solutions are jeopardizing patient care and placing a strain on hospital operations, according to a report published by the American Society of Health-System Pharmacists (ASHP).

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Galcanezumab Beats Placebo for Episodic Migraine

THURSDAY, May 31, 2018 (HealthDay News) -- For patients with episodic migraine, galcanezumab is better than placebo for reducing migraine headache days, according to a study published online May 29 in JAMA Neurology.

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Review IDs Exercise 'Dose' That May Improve Cognition in Seniors

THURSDAY, May 31, 2018 (HealthDay News) -- For older adults, exercise is associated with improved cognition, with exercising for at least 52 hours over a six month period for about an hour each session associated with improved cognitive skills, according to a review published online May 30 in Neurology: Clinical Practice.

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CDC: Outpatient Rehab Rates Suboptimal for Stroke Survivors

WEDNESDAY, May 30, 2018 (HealthDay News) -- In 2015, 35.5 percent of adult stroke survivors used outpatient rehabilitation, up from 31.2 percent in 2013, according to research published in the May 25 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Severe Hyponatremia Described After Drinking Horsetail Juice

TUESDAY, May 29, 2018 (HealthDay News) -- Severe hyponatremia has been described after drinking horsetail (Equisetum) juice in a case report published online May 29 in the Annals of Internal Medicine.

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Associative Memory Test Aids Prediction of Dementia Risk

TUESDAY, May 29, 2018 (HealthDay News) -- Among older adults with a minor decline on a screening test for cognitive ability, an additional three-minute test of associative memory can improve identification of patients at increased risk of developing dementia over the next several years, according to a study published in the May/June issue of the Annals of Family Medicine.

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Insomnia Found to Be Common but Mild in Older Adults

TUESDAY, May 29, 2018 (HealthDay News) -- Insomnia is common in older community-dwelling adults, but usually mild, according to a study published online May 21 in the Journal of the American Geriatrics Society.

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Gaps in Care Post Discharge for Mild Traumatic Brain Injury

TUESDAY, May 29, 2018 (HealthDay News) -- There are considerable gaps in follow-up care for patients with mild traumatic brain injury (mTBI) who have been discharged from the hospital, according to a study published online May 25 in JAMA Network Open.

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Early-Life Weight Associated With Cognitive Factors

FRIDAY, May 25, 2018 (HealthDay News) -- Early-life weight status has an inverse association with some cognitive abilities in children, according to a study published online May 23 in Obesity.

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Congress Approves Bill Expanding Private Care for VA Patients

THURSDAY, May 24, 2018 (HealthDay News) -- Patients served by the beleaguered Veterans Affairs health system may have wider access to private care, thanks to a bill approved Wednesday by the Senate. President Donald Trump is known to support the bill, which now awaits his signature.

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Neurologists Identify New Type of Vertigo

THURSDAY, May 24, 2018 (HealthDay News) -- A hyperactive and asymmetric velocity-storage mechanism may be responsible for intermittent attacks of vertigo in some patients with recurrent spontaneous vertigo (RSV) of unknown etiology, according to a study published online May 23 in Neurology.

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Global Variation in Personal Health Care Access and Quality

THURSDAY, May 24, 2018 (HealthDay News) -- There is considerable global variation in personal health care access and quality, according to a study published online May 23 in The Lancet.

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CDC: No Change in Level of Uninsured in U.S. in 2017

TUESDAY, May 22, 2018 (HealthDay News) -- Overall, 9.1 percent of individuals in the United States were uninsured in 2017, which was not significantly different from the level in 2016, according to a report published online May 22 by the U.S. Centers for Disease Control and Prevention's National Centers for Health Statistics.

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IBD Associated With Increased Risk of Parkinson's Disease

TUESDAY, May 22, 2018 (HealthDay News) -- There is a significantly increased risk of Parkinson's disease (PD) in patients with inflammatory bowel disease (IBD), according to a study published online May 21 in Gut.

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Social, Communication Delays With False-Negative on M-CHAT

MONDAY, May 21, 2018 (HealthDay News) -- Children who pass the Modified Checklist for Autism in Toddlers (M-CHAT) screening at 18 months but later receive diagnoses of autism spectrum disorder (ASD) exhibit delays in social, communication, and motor skills, according to a study published online May 21 in Pediatrics.

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FDA Approves Aimovig to Prevent Migraines

MONDAY, May 21, 2018 (HealthDay News) -- Aimovig (erenumab-aooe) has been approved by the U.S. Food and Drug Administration to prevent migraine headaches in adults.

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Various Clinical Disturbances Precede MS Diagnosis

FRIDAY, May 18, 2018 (HealthDay News) -- Various clinical symptoms precede the diagnosis of multiple sclerosis (MS) by several years, according to a study published online May 8 in the Annals of Neurology.

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Language Used in Medical Record Can Affect Patient Care

FRIDAY, May 18, 2018 (HealthDay News) -- Stigmatizing language used in medical records to describe patients can influence medical students and residents in terms of their attitudes towards the patient and their clinical decision-making, according to a study published in the May issue of the Journal of General Internal Medicine.

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Aerobic + Strength Exercise Doesn't Slow Cognitive Decline

THURSDAY, May 17, 2018 (HealthDay News) -- An aerobic and strength exercise program does not slow cognitive impairment among people with mild-to-moderate dementia, according to a study published online May 16 in The BMJ.

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Seafood Recommended 1 to 2 Times/Week for Cardiac Benefit

THURSDAY, May 17, 2018 (HealthDay News) -- One to two servings of seafood per week is recommended for cardiovascular benefits, according to an American Heart Association science advisory published online May 17 in Circulation.

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Addition of Cannabidiol May Cut Drop Seizures in Lennox-Gastaut

WEDNESDAY, May 16, 2018 (HealthDay News) -- The addition of cannabidiol to conventional antiepileptic medication is associated with a reduction in the frequency of drop seizures among patients with Lennox-Gastaut syndrome, according to a study published in the May 17 issue of the New England Journal of Medicine.

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Nonprofit Manufacturer Could Keep Generic Drug Costs Down

WEDNESDAY, May 16, 2018 (HealthDay News) -- A nonprofit manufacturer could help keep generic drug prices down and maintain their supply, according to a perspective piece published in the May 17 issue of the New England Journal of Medicine.

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Better Diet Quality Associated With Larger Brain Volume

WEDNESDAY, May 16, 2018 (HealthDay News) -- Better diet quality, including high intake of vegetables, fruit, whole grains, dairy, nuts, and fish, is associated with larger brain volume, according to a study published online May 16 in Neurology.

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Fremanezumab Linked to Fewer Monthly Migraine Days

WEDNESDAY, May 16, 2018 (HealthDay News) -- For patients with episodic migraine, fremanezumab is associated with a reduction in the mean number of monthly migraine days, according to a study published in the May 15 issue of the Journal of the American Medical Association.

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Best Practices Developed for Use of EHR to Enhance Patient Care

WEDNESDAY, May 16, 2018 (HealthDay News) -- Best practices have been developed for using electronic health records (EHRs) to enhance patient-centered care, according to an article published online in Medical Economics.

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Disruption of Circadian Rhythm Negatively Impacts Mental Health

WEDNESDAY, May 16, 2018 (HealthDay News) -- Circadian disruption and lower relative amplitude are both associated with higher risk of susceptibility to mental health issues, according to a study published online May 15 in The Lancet Psychiatry.

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Peripheral Neuropathy Common in Childhood Cancer Survivors

TUESDAY, May 15, 2018 (HealthDay News) -- Childhood cancer survivors frequently have clinical abnormalities attributable to peripheral neuropathy, according to a study published online May 14 in JAMA Neurology.

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FDA Expands Use of MS Drug to Include Children

MONDAY, May 14, 2018 (HealthDay News) -- The U.S. Food and Drug Administration has expanded its approval of the multiple sclerosis drug Gilenya (fingolimod) to include children aged 10 and older.

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Study IDs Factors Linked to Quality of Life With Dementia

MONDAY, May 14, 2018 (HealthDay News) -- Good relationships, social engagement, better every day functioning, good physical and mental health, and high-quality care are linked to better quality of life (QoL) for patients with dementia, according to a review published online May 8 in Psychological Medicine.

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Rate of Deaths From Falls in Seniors Up From 2007 to 2016

MONDAY, May 14, 2018 (HealthDay News) -- From 2007 to 2016, the rate of deaths from falls among older adults increased by an average of 3.0 percent per year, according to research published in the May 11 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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FDA Targets Clinics Offering Unapproved Stem Cell Therapies

THURSDAY, May 10, 2018 (HealthDay News) -- The U.S. Food and Drug Administration has launched legal action to stop two stem cell clinics from providing unapproved treatments that have caused serious, long-term harm to some patients.

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Age of First Football Tackles Tied to Neuro Symptom Onset

THURSDAY, May 10, 2018 (HealthDay News) -- Younger age of exposure to tackle football predicts earlier neurobehavioral symptom onset among players with chronic traumatic encephalopathy (CTE), according to a study published online April 30 in the Annals of Neurology.

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Depressive Symptoms Tied to Memory, Aging of the Brain

WEDNESDAY, May 9, 2018 (HealthDay News) -- Greater depressive symptoms are associated with episodic memory and markers of brain aging in older Caribbean Hispanic patients, according to a study published online May 9 in Neurology.

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Women Have Stronger Link Between APOE-ε4, CSF Tau Levels

WEDNESDAY, May 9, 2018 (HealthDay News) -- The correlation between the apolipoprotein E (APOE) gene allele APOE-ε4 and cerebrospinal fluid (CSF) tau levels is stronger among women than men, according to a study published online May 7 in JAMA Neurology.

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Crowdfunding Exaggerates Efficacy of Unproven Stem Cell Tx

WEDNESDAY, May 9, 2018 (HealthDay News) -- Crowdfunding campaigns for unproven stem cell-based interventions tend to exaggerate the efficacy and underemphasize the risks, according to a research letter published in the May 8 issue of the Journal of the American Medical Association.

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Surgery for Hip Fx Cuts Mortality in NH Residents With Dementia

WEDNESDAY, May 9, 2018 (HealthDay News) -- For nursing home (NH) residents with dementia and hip fracture, surgical hip fracture repair is associated with lower mortality, according to a study published online May 7 in JAMA Internal Medicine.

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Regulatory Requirements Drive Dissatisfaction With EHRs

TUESDAY, May 8, 2018 (HealthDay News) -- Regulatory requirements are likely to be an important aspect of physician dissatisfaction with electronic health records (EHRs) that is driving burnout, according to an Ideas and Opinions piece published online May 8 in the Annals of Internal Medicine.

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Approaches to Firearms for Persons With Dementia Discussed

TUESDAY, May 8, 2018 (HealthDay News) -- Approaches to addressing the potential complications of owning firearms for persons with dementia (PWD) are presented in an article published online May 8 in the Annals of Internal Medicine.

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Risk of Pediatric Mental Illness Up After Injury Hospitalization

TUESDAY, May 8, 2018 (HealthDay News) -- Medicaid-insured children are at increased risk for mental health diagnoses and psychotropic prescriptions after hospitalization for an injury compared with pre-hospitalization, according to a study published online May 7 in The Journal of Pediatrics.

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Mild TBI Linked to Increased Dementia Risk in Veterans

MONDAY, May 7, 2018 (HealthDay News) -- Even mild traumatic brain injury (TBI) without loss of consciousness (LOC) is associated with increased risk of dementia among veterans, according to a study published online May 7 in JAMA Neurology.

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Folic Acid May Cut Stroke Risk in High-Risk Hypertensive Patients

MONDAY, May 7, 2018 (HealthDay News) -- Hypertensive patients may lower their stroke risk with folic acid supplements, according to a study published in the May 15 issue of the Journal of the American College of Cardiology.

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Many Organizations Not Meeting Trial Reporting Requirements

FRIDAY, May 4, 2018 (HealthDay News) -- Many organizations are not meeting the trial registration and results reporting requirements clarified by "The Final Rule," which had a compliance date of April 18, 2017, according to a study published online May 1 in BMC Medicine.

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Study IDs Pain Descriptors for Varying Stages of Low Back Pain

FRIDAY, May 4, 2018 (HealthDay News) -- Varying pain descriptors may be useful when evaluating patients with different stages of low back pain (LBP), according to a study published online April 30 in PAIN Practice.

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Obstructive Sleep Apnea Linked to Thinning of Calvaria, Skull Base

FRIDAY, May 4, 2018 (HealthDay News) -- Obstructive sleep apnea (OSA) is associated with thinning of the calvaria and skull base, according to a study published online May 3 in JAMA Otolaryngology-Head & Neck Surgery.

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Physical Therapy Helps Recover Arm Function in Chronic CVA

FRIDAY, May 4, 2018 (HealthDay News) -- Physical therapy promotes the recovery of arm function and neuroplasticity in all chronic stroke patients, according to a study published online April 25 in the Journal of Evaluation in Clinical Practice.

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Lightning Can Affect Deep Brain Stimulation Devices

THURSDAY, May 3, 2018 (HealthDay News) -- Lightning, which can result in strong electromagnetic fields (EMFs), can interfere with deep brain stimulation (DBS) devices, according to a case report published online May 1 in the Journal of Neurosurgery.

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Frequency of Sauna Bathing Linked to Reduced Stroke Risk

WEDNESDAY, May 2, 2018 (HealthDay News) -- For adults, frequent sauna bathing is associated with reduced risk of future stroke, according to a study published online May 2 in Neurology.

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DRESS Prototype Promising for Persons With Dementia

WEDNESDAY, May 2, 2018 (HealthDay News) -- For persons with dementia, a prototype intelligent system, the DRESS prototype, can provide automated dressing support by identifying incorrect dressing scenarios, according to a study published in the April-June issue of JMIR Medical Informatics.

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Palliative Care Consult Can Cut Hospital Costs in Seriously Ill

WEDNESDAY, May 2, 2018 (HealthDay News) -- For hospitalized adults with serious illness, receiving a palliative care consultation (PCC) is associated with a reduction in hospital costs, according to a review published online April 30 in JAMA Internal Medicine.

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Epilepsy Does Not Appear to Affect Likelihood of Pregnancy

WEDNESDAY, May 2, 2018 (HealthDay News) -- Women with epilepsy and no history of infertility have a similar likelihood of achieving pregnancy as peers without epilepsy, according to a study published online April 30 in JAMA Neurology.

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Practices Should Be Aware of Correct Way to Fire Employees

TUESDAY, May 1, 2018 (HealthDay News) -- Physicians should be aware of the correct protocol for, as well as the laws involved in, firing employees, according to a report published in Medical Economics.

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Clinically Significant Anxiety Tied to Subsequent Dementia Risk

TUESDAY, May 1, 2018 (HealthDay News) -- Clinically significant anxiety in midlife is associated with increased subsequent dementia risk over an interval of at least 10 years, according to a review published online April 30 in BMJ Open.

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Anesthesia Before Age 3 Not Linked to Intelligence Deficits

TUESDAY, May 1, 2018 (HealthDay News) -- Multiple exposures to anesthesia before the age of 3 years may have neuropsychological impacts, though intelligence does not appear to be affected, according to a study published online April 18 in Anesthesiology.

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Maternal, Child Sugar Intake Could Impact Child Cognition

TUESDAY, May 1, 2018 (HealthDay News) -- Greater sugar consumption during pregnancy and early childhood may adversely impact child cognition, according to a study published online April 16 in the American Journal of Preventive Medicine.

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Perioperative MACCEs More Common With Diabetes

TUESDAY, May 1, 2018 (HealthDay News) -- Perioperative major adverse cardiovascular and cerebrovascular events (MACCEs) are more common among patients with diabetes mellitus (DM), according to a study published online April 4 in Diabetes Care.

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