May 2018 Briefing - Internal Medicine

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Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for May 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Comprehensive Primary Care Initiative Improves Care Delivery

THURSDAY, May 31, 2018 (HealthDay News) -- Introducing the Comprehensive Primary Care Initiative (CPC), a health care delivery model developed by the Centers for Medicare and Medicaid Services (CMS), improves primary care delivery but does not reduce Medicare spending enough to cover care management fees, according to a study published online May 23 in Health Affairs.

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No Consistent Cardiovascular Benefit Seen for Supplements

THURSDAY, May 31, 2018 (HealthDay News) -- The data on popular supplements show no consistent cardiovascular benefit, according to a study published in the June 5 issue of the Journal of the American College of Cardiology.

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Prompts May Up Goals-of-Care Dialogues at Outpatient Visits

THURSDAY, May 31, 2018 (HealthDay News) -- A patient-specific preconversation communication-priming intervention targeting patients and clinicians is associated with an increase in goals-of-care discussions among patients with serious illness, according to a study published online May 26 in JAMA Internal Medicine.

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Review IDs Exercise 'Dose' That May Improve Cognition in Seniors

THURSDAY, May 31, 2018 (HealthDay News) -- For older adults, exercise is associated with improved cognition, with exercising for at least 52 hours over a six month period for about an hour each session associated with improved cognitive skills, according to a review published online May 30 in Neurology: Clinical Practice.

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T1DM Self-Management Varies With Adult Developmental Stages

THURSDAY, May 31, 2018 (HealthDay News) -- Type 1 diabetes self-management behaviors vary across adult developmental stages, according to a study published online May 25 in Diabetes Care.

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CVD Risk Up Even in Metabolically Healthy Obese Women

THURSDAY, May 31, 2018 (HealthDay News) -- Obesity is associated with increased risk of cardiovascular disease risk even among metabolically healthy women, according to a study published online May 30 in The Lancet Diabetes & Endocrinology.

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ASHP: SVP, Injectable Opioid Shortages Threaten Patient Care

THURSDAY, May 31, 2018 (HealthDay News) -- The widespread shortages of injectable opioids and small-volume parenteral (SVP) solutions are jeopardizing patient care and placing a strain on hospital operations, according to a report published by the American Society of Health-System Pharmacists (ASHP).

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Galcanezumab Beats Placebo for Episodic Migraine

THURSDAY, May 31, 2018 (HealthDay News) -- For patients with episodic migraine, galcanezumab is better than placebo for reducing migraine headache days, according to a study published online May 29 in JAMA Neurology.

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Annual Health Care Expenditure Higher for Hypertensive Patients

WEDNESDAY, May 30, 2018 (HealthDay News) -- Individuals with hypertension have a higher annual adjusted incremental expenditure of $1,920, according to a study published online May 30 in the Journal of the American Heart Association.

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Older Adults Often Reluctant to Set Up Secure Patient Portal

WEDNESDAY, May 30, 2018 (HealthDay News) -- About half of older adults report having set up a patient portal, according to survey results from the National Poll on Healthy Aging.

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ACS Updates Colorectal Cancer Screening to Start at Age 45

WEDNESDAY, May 30, 2018 (HealthDay News) -- Colorectal cancer (CRC) screening should begin at age 45 for people at average risk, according to updated guidelines from the American Cancer Society published online May 30 in CA: A Cancer Journal for Clinicians.

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Birth Control Pills Recalled Over Potential Pregnancy Risk

WEDNESDAY, May 30, 2018 (HealthDay News) -- Almost 170,000 birth control pill packs are being recalled over a manufacturing error that could lead to unplanned pregnancy, maker Allergan says.

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Elevated HbA1c Usually Leads to Prompt Tx Start, Intensification

WEDNESDAY, May 30, 2018 (HealthDay News) -- Most patients are newly initiated on antidiabetic therapy or have antidiabetic therapy intensified within six months of hemoglobin A1c (HbA1c) elevation, according to a study published online May 24 in Diabetes Care.

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Genomic Medicine Will Help Shift Cardio Care to Proactive Approach

WEDNESDAY, May 30, 2018 (HealthDay News) -- Genomic medicine is likely to help clinical care shift from a reactive to a proactive approach, especially in the field of cardiovascular medicine, according to a scientific statement from the American Heart Association published online May 29 in Circulation: Genomic and Precision Medicine.

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Does Higher Protein Intake Up Heart Failure Risk in Men?

WEDNESDAY, May 30, 2018 (HealthDay News) -- Higher dietary protein intake is associated with a trend toward increased heart failure risk among middle-aged men, according to a study published online May 29 in Circulation: Heart Failure.

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Recommendations Developed for Improving Women's Health Care

WEDNESDAY, May 30, 2018 (HealthDay News) -- Women face unique health challenges across their lifetimes, and policies should be implemented to improve their health outcomes, according to a position paper published online May 29 in the Annals of Internal Medicine.

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CDC: Outpatient Rehab Rates Suboptimal for Stroke Survivors

WEDNESDAY, May 30, 2018 (HealthDay News) -- In 2015, 35.5 percent of adult stroke survivors used outpatient rehabilitation, up from 31.2 percent in 2013, according to research published in the May 25 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Tighter Alcohol Policies Cut Alcohol-Related Crash Deaths

WEDNESDAY, May 30, 2018 (HealthDay News) -- Strengthening state alcohol policies can reduce alcohol-related crash fatalities, according to a study published online May 29 in JAMA Internal Medicine.

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Severe Hyponatremia Described After Drinking Horsetail Juice

TUESDAY, May 29, 2018 (HealthDay News) -- Severe hyponatremia has been described after drinking horsetail (Equisetum) juice in a case report published online May 29 in the Annals of Internal Medicine.

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Associative Memory Test Aids Prediction of Dementia Risk

TUESDAY, May 29, 2018 (HealthDay News) -- Among older adults with a minor decline on a screening test for cognitive ability, an additional three-minute test of associative memory can improve identification of patients at increased risk of developing dementia over the next several years, according to a study published in the May/June issue of the Annals of Family Medicine.

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One in Six Women Regret Freezing Their Eggs

TUESDAY, May 29, 2018 (HealthDay News) -- Certain identifiable factors are associated with decision regret following elective oocyte cryopreservation (EOC), according to a study published online May 25 in Fertility and Sterility.

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Gaps in Care Post Discharge for Mild Traumatic Brain Injury

TUESDAY, May 29, 2018 (HealthDay News) -- There are considerable gaps in follow-up care for patients with mild traumatic brain injury (mTBI) who have been discharged from the hospital, according to a study published online May 25 in JAMA Network Open.

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Reduced-Dose Anticoagulants Feasible for Extended VTE Tx

TUESDAY, May 29, 2018 (HealthDay News) -- For an extended duration, reduced-dose direct oral anticoagulants (DOACs) may be as effective as full-dose treatment for preventing recurrent venous thromboembolism (VTE), according to a review published online May 17 in the Journal of Thrombosis and Haemostasis.

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Insomnia Found to Be Common but Mild in Older Adults

TUESDAY, May 29, 2018 (HealthDay News) -- Insomnia is common in older community-dwelling adults, but usually mild, according to a study published online May 21 in the Journal of the American Geriatrics Society.

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Mini-Dose Glucagon May Halt Post-Exercise Hypoglycemia

TUESDAY, May 29, 2018 (HealthDay News) -- Mini-dose glucagon (MDG) is an effective approach for preventing exercise-induced hypoglycemia in patients with type 1 diabetes, according to a study published online May 18 in Diabetes Care.

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New Hypertension Guideline Discussed for Older Adults

TUESDAY, May 29, 2018 (HealthDay News) -- Clinicians caring for older adults with hypertension should be mindful of the specific blood pressure (BP) goals proven to reduce cardiovascular disease events, while adopting the new 2017 American College of Cardiology/American Heart Association (ACC/AHA) hypertension guideline, according to an article published online May 20 in the Journal of the American Geriatrics Society.

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Increase in Tx Candidates With 2017 Hypertension Guidelines

FRIDAY, May 25, 2018 (HealthDay News) -- The 2017 American College of Cardiology/American Heart Association hypertension guideline is associated with an increase in the proportion of adults recommended for antihypertensive treatment compared with the 2014 guideline, according to a study published online May 23 in JAMA Cardiology.

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FDA Approves Palynziq for Phenylketonuria

FRIDAY, May 25, 2018 (HealthDay News) -- Palynziq (pegvaliase-pqpz) has been approved by the U.S. Food and Drug Administration to treat phenylketonuria, or PKU.

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CDC IDs Outbreak Trends Tied to Treated Recreational Water

FRIDAY, May 25, 2018 (HealthDay News) -- Outbreaks associated with treated recreational water with confirmed infectious etiology are usually caused by Cryptosporidium, Legionella, or Pseudomonas, according to research published in the May 18 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Certolizumab Looks Promising for Moderate-to-Severe Psoriasis

FRIDAY, May 25, 2018 (HealthDay News) -- Twice-weekly certolizumab biologic appears to be both safe and effective for the treatment of moderate-to-severe chronic plaque psoriasis, according to a study published online April 13 in the Journal of the American Academy of Dermatology.

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Mortality Still High After Surgery for Congenital Heart Defects

FRIDAY, May 25, 2018 (HealthDay News) -- Long-term mortality after congenital heart surgery is higher than that of the general population for all forms of congenital heart defects (CHDs), according to a study published in the May 29 issue of the Journal of the American College of Cardiology.

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CPAP Use May Improve Sexual QOL in Those With Sleep Apnea

FRIDAY, May 25, 2018 (HealthDay News) -- Successful continuous positive airway pressure (CPAP) use for obstructive sleep apnea may be associated with improved sexual quality of life (QOL), according to a study published online May 24 in JAMA Otolaryngology-Head & Neck Surgery.

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Antidepressant Prescribing Linked to Lasting Weight Gain

FRIDAY, May 25, 2018 (HealthDay News) -- Antidepressant prescribing is associated with long-term increased risk of weight gain, according to a study published online May 23 in The BMJ.

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Severe Atopic Eczema Tied to Higher CV Disease Risk

FRIDAY, May 25, 2018 (HealthDay News) -- Adults with severe atopic eczema are at increased risk of cardiovascular disease, according to a study published online May 23 in The BMJ.

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Laws Allowing Service Denial to Sexual Minorities Tied to Distress

FRIDAY, May 25, 2018 (HealthDay News) -- Laws permitting denial of services to same-sex couples are associated with an increase in sexual minority adults experiencing mental distress, according to a study published online May 23 in JAMA Psychiatry.

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Non-Nutritive Sweeteners Don't Up Blood Glucose Levels

FRIDAY, May 25, 2018 (HealthDay News) -- Consumption of non-nutritive sweeteners (NNSs) does not increase blood glucose levels, according to a review published online May 15 in the European Journal of Clinical Nutrition.

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Congress Approves Bill Expanding Private Care for VA Patients

THURSDAY, May 24, 2018 (HealthDay News) -- Patients served by the beleaguered Veterans Affairs health system may have wider access to private care, thanks to a bill approved Wednesday by the Senate. President Donald Trump is known to support the bill, which now awaits his signature.

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Rising Fatal Drug Overdoses Linked to Years of Life Lost

THURSDAY, May 24, 2018 (HealthDay News) -- For non-Hispanic whites, rising fatal drug overdose rates are associated with increases in the mortality rate and years of potential life lost from 1999 to 2015, according to a study published online May 22 in the American Journal of Preventive Medicine.

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Atherosclerotic CVD Mortality Higher in South Asians in the U.S.

THURSDAY, May 24, 2018 (HealthDay News) -- South Asians in the United States have increased proportional mortality rates from atherosclerotic cardiovascular disease (ASCVD), although there are no unique risk factors in this population, according to a scientific statement from the American Heart Association published online May 24 in Circulation.

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Financial Incentives May Up Rates of Smoker Abstinence

THURSDAY, May 24, 2018 (HealthDay News) -- Financial incentives added to free cessation aids can improve the rate of sustained abstinence among smokers, according to a study published online May 23 in the New England Journal of Medicine.

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Social Isolation Tied to Worse Heart Failure Outcomes

THURSDAY, May 24, 2018 (HealthDay News) -- Greater perceived social isolation is associated with an increased risk of death and health care use among patients with heart failure, according to a study published online May 23 in the Journal of the American Heart Association.

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Global Variation in Personal Health Care Access and Quality

THURSDAY, May 24, 2018 (HealthDay News) -- There is considerable global variation in personal health care access and quality, according to a study published online May 23 in The Lancet.

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12 County-Level Factors Affect Individual Well-Being in U.S.

WEDNESDAY, May 23, 2018 (HealthDay News) -- Twelve county-level factors, including social and economic, clinical care, and physical environment, explain the majority of variation in resident well-being in the United States, according to a study published online May 23 in PLOS ONE.

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Lung Cancer Incidence Higher for Young Women Than Young Men

WEDNESDAY, May 23, 2018 (HealthDay News) -- Lung cancer incidence is higher among young women than young men, according to a study published in the May 24 issue of the New England Journal of Medicine.

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Extended INR Test Intervals Safe for Warfarin-Treated Patients

WEDNESDAY, May 23, 2018 (HealthDay News) -- For stable warfarin-treated patients, extended international normalized ratio (INR) testing can be successfully and safely implemented, according to a study published online May 15 in the Journal of Thrombosis and Haemostasis.

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Morbidity in Pregnancy Common for Women With Heart Disease

WEDNESDAY, May 23, 2018 (HealthDay News) -- For women with heart disease, cardiac complications occur in 16 percent of pregnancies and are mainly linked to arrhythmias and heart failure, according to a study published in the May 29 issue of the Journal of the American College of Cardiology.

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Inverse Link for Plasma 25(OH)D Concentration, Risk of T2DM

WEDNESDAY, May 23, 2018 (HealthDay News) -- There is an inverse association for plasma 25-hydroxyvitamin D (25[OH]D) concentration with diabetes risk, according to a study published online April 19 in PLOS ONE.

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Less Driving Tied to Lower Cardiovascular Disease Risk

WEDNESDAY, May 23, 2018 (HealthDay News) -- More active alternatives to the car for travel are associated with a reduced risk of cardiovascular disease (CVD) and all-cause mortality, according to a study published online May 21 in Heart.

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Better Social Support Network Protects Black Men Against HIV

WEDNESDAY, May 23, 2018 (HealthDay News) -- A better social support network may help protect black men who have sex with men (BMSM) against HIV acquisition, according to a study published in the June issue of the Journal of Acquired Immune Deficiency Syndrome.

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Post-Surgical Readmissions Higher Among Homeless Veterans

TUESDAY, May 22, 2018 (HealthDay News) -- Readmissions are higher in homeless veterans discharged to the community after surgery, compared to housed veterans, according to a study published in the June issue of Medical Care.

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Daily Egg Consumption Linked to Reduced CVD Risk

TUESDAY, May 22, 2018 (HealthDay News) -- A moderate level of egg consumption is associated with a reduced risk of cardiovascular disease (CVD), according to a study published online May 21 in Heart.

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IBD Associated With Increased Risk of Parkinson's Disease

TUESDAY, May 22, 2018 (HealthDay News) -- There is a significantly increased risk of Parkinson's disease (PD) in patients with inflammatory bowel disease (IBD), according to a study published online May 21 in Gut.

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From 2008 to 2014, Prostate Cancer Testing, Treatment Down

TUESDAY, May 22, 2018 (HealthDay News) -- Fewer men are being screened for, diagnosed with, and treated for prostate cancer, according to a study published online May 21 in Cancer.

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2003 to 2014 Saw Rise in Diabetic Ketoacidosis Admissions

TUESDAY, May 22, 2018 (HealthDay News) -- The incidence of hospitalization for diabetic ketoacidosis (DKA) and associated costs increased from 2003 to 2014, according to a study published online May 17 in Diabetes Care.

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Moral Distress for Docs Providing Emergency-Only Hemodialysis

TUESDAY, May 22, 2018 (HealthDay News) -- Clinicians who provide emergency-only hemodialysis (EOHD) to undocumented immigrants experience moral distress and professional burnout, according to a study published online May 22 in the Annals of Internal Medicine.

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CDC: No Change in Level of Uninsured in U.S. in 2017

TUESDAY, May 22, 2018 (HealthDay News) -- Overall, 9.1 percent of individuals in the United States were uninsured in 2017, which was not significantly different from the level in 2016, according to a report published online May 22 by the U.S. Centers for Disease Control and Prevention's National Centers for Health Statistics.

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Exercise Modifies Predisposition to Obesity After Menopause

TUESDAY, May 22, 2018 (HealthDay News) -- Physical activity modifies the association between the body mass index (BMI) genetic risk score (GRS) and BMI, according to a study published online May 16 in Menopause.

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Patterns of Potential Misuse Help Assess Risk of Opioid Overdose

MONDAY, May 21, 2018 (HealthDay News) -- Patterns of potential opioid misuse are positively associated with subsequent opioid overdose, according to a study published online May 22 in the Annals of Internal Medicine.

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FDA Approves Aimovig to Prevent Migraines

MONDAY, May 21, 2018 (HealthDay News) -- Aimovig (erenumab-aooe) has been approved by the U.S. Food and Drug Administration to prevent migraine headaches in adults.

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Risk of Dementia Up for Older Adults With Lowest Wealth

MONDAY, May 21, 2018 (HealthDay News) -- The risk of dementia is increased for adults in the lowest versus the highest wealth quintile, according to a study published online May 16 in JAMA Psychiatry.

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Robust Immune Responses for Herpes Zoster Subunit Vaccine

MONDAY, May 21, 2018 (HealthDay News) -- Recipients of the herpes zoster subunit vaccine (HZ/su), consisting of varicella-zoster virus glycoprotein E (gE) and AS01B Adjuvant System, develop robust immune responses, according to a study published in the June 1 issue of The Journal of Infectious Diseases.

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Starting Exercise Even in Older Age Cuts Heart Failure Risk

MONDAY, May 21, 2018 (HealthDay News) -- Increasing patients' physical activity is an effective strategy to lower future risk of heart failure, according to a study published in the May issue of Circulation.

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Depression-Heart Rate Variability Link Is Bidirectional

MONDAY, May 21, 2018 (HealthDay News) -- There is a bidirectional association between depression and heart rate variability (HRV), according to a study published online May 16 in JAMA Psychiatry.

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Rivaroxaban Linked to Low VTE Recurrence in Active Cancer

MONDAY, May 21, 2018 (HealthDay News) -- For patients with active cancer and venous thromboembolism (VTE), rivaroxaban is associated with lower VTE recurrence compared with dalteparin, but with elevated clinically relevant non-major bleeding (CRNMB), according to a study published online May 10 in the Journal of Clinical Oncology.

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Semaglutide Found to Be Effective Against Type 2 Diabetes

MONDAY, May 21, 2018 (HealthDay News) -- Semaglutide is safe and effective for the treatment of type 2 diabetes, according to a review published online May 13 in Diabetes, Obesity and Metabolism.

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Over Half of Young Adult Smoke Volume Exposure From Hookahs

FRIDAY, May 18, 2018 (HealthDay News) -- Waterpipe tobacco smoking (or hookah smoking) accounts for half of young adults' tobacco smoke exposure, according to a study published online May 16 in Tobacco Control.

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Various Clinical Disturbances Precede MS Diagnosis

FRIDAY, May 18, 2018 (HealthDay News) -- Various clinical symptoms precede the diagnosis of multiple sclerosis (MS) by several years, according to a study published online May 8 in the Annals of Neurology.

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Language Used in Medical Record Can Affect Patient Care

FRIDAY, May 18, 2018 (HealthDay News) -- Stigmatizing language used in medical records to describe patients can influence medical students and residents in terms of their attitudes towards the patient and their clinical decision-making, according to a study published in the May issue of the Journal of General Internal Medicine.

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Pharmacists Should Counsel Patients Fasting for Ramadan

FRIDAY, May 18, 2018 (HealthDay News) -- Pharmacists should counsel Muslim patients who fast during Ramadan with respect to their medications and adjusting their medication regimen, according to an article published in Drug Topics.

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Adding Chiropractic to Usual Care Beneficial for Low Back Pain

FRIDAY, May 18, 2018 (HealthDay News) -- For active-duty military personnel, the addition of chiropractic care to usual medical care is associated with improvements in low back pain intensity and disability, according to a study published online May 18 in JAMA Network Open.

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Breath Test Shows Promise for Diagnosis of Esophagogastric CA

FRIDAY, May 18, 2018 (HealthDay News) -- Breath analysis shows potential for noninvasive diagnosis of esophagogastric cancer (OGC), according to a study published online May 17 in JAMA Oncology.

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Chemicals in Hair Products for Black Women Raise Concerns

FRIDAY, May 18, 2018 (HealthDay News) -- Multiple chemicals associated with endocrine disruption and asthma are contained in hair products used by black women and children, according to a study published online April 25 in Environmental Research.

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Higher Adiposity Increases Odds of Smoking

FRIDAY, May 18, 2018 (HealthDay News) -- Obesity is linked to an increased risk of smoking and an increase in the number of cigarettes smoked daily, according to a study published online May 16 in The BMJ.

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Ischemic Heart Disease, CHF Mortality Vary Across VA Systems

FRIDAY, May 18, 2018 (HealthDay News) -- Risk-standardized mortality rates for ischemic heart disease (IHD) and chronic heart failure vary across Veterans Affairs Medical Centers (VAMCs), according to a study published online May 16 in JAMA Cardiology.

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Acute Kidney Injury in Hospital Ups Risk of Later Heart Failure

THURSDAY, May 17, 2018 (HealthDay News) -- Acute kidney injury (AKI) is independently associated with a higher risk of cardiovascular events, especially heart failure, after hospital discharge, according to a study published online May 17 in the Clinical Journal of the American Society of Nephrology.

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Good Evidence That HPV Vaccines Protect Against Cervical Precancer

THURSDAY, May 17, 2018 (HealthDay News) -- Human papillomavirus (HPV) vaccines protect against cervical precancer in adolescent girls and young women, according to a review published online May 9 in the Cochrane Library.

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FDA Approves Non-Opioid Treatment for Opioid Withdrawal

THURSDAY, May 17, 2018 (HealthDay News) -- Lucemyra (lofexidine hydrochloride) has been approved by the U.S. Food and Drug Administration to treat symptoms of opioid withdrawal.

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More Variants in DCM-Tied Genes in Alcoholic Cardiomyopathy

THURSDAY, May 17, 2018 (HealthDay News) -- Patients with alcoholic cardiomyopathy (ACM) have more variants in dilated cardiomyopathy (DCM)-associated genes than those without ACM, according to a study published in the May 22 issue of the Journal of the American College of Cardiology.

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Healthful Diet Linked to Reduced Risk of Hearing Loss in Women

THURSDAY, May 17, 2018 (HealthDay News) -- For women, adherence to healthful dietary patterns is associated with reduced risk of hearing loss, according to a study published online May 11 in the Journal of Nutrition.

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CDC: Number of U.S. Births Dropped to 30-Year Low in 2017

THURSDAY, May 17, 2018 (HealthDay News) -- The number of U.S. births decreased in 2017, reaching a 30-year low, according to a report published online May 17 by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics.

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Aerobic + Strength Exercise Doesn't Slow Cognitive Decline

THURSDAY, May 17, 2018 (HealthDay News) -- An aerobic and strength exercise program does not slow cognitive impairment among people with mild-to-moderate dementia, according to a study published online May 16 in The BMJ.

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Seafood Recommended 1 to 2 Times/Week for Cardiac Benefit

THURSDAY, May 17, 2018 (HealthDay News) -- One to two servings of seafood per week is recommended for cardiovascular benefits, according to an American Heart Association science advisory published online May 17 in Circulation.

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Budesonide-Formoterol Used As Needed Beneficial in Mild Asthma

THURSDAY, May 17, 2018 (HealthDay News) -- Inhaled combined budesonide-formoterol used as needed is beneficial for mild asthma, according to two studies published in the May 17 issue of the New England Journal of Medicine.

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Sustained Use of Oxymetazoline Cream Efficacious for Rosacea

THURSDAY, May 17, 2018 (HealthDay News) -- Oxymetazoline is safe and effective for the treatment of moderate-to-severe persistent erythema of rosacea, according to a study published in the June issue of the Journal of the American Academy of Dermatology.

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Addition of Cannabidiol May Cut Drop Seizures in Lennox-Gastaut

WEDNESDAY, May 16, 2018 (HealthDay News) -- The addition of cannabidiol to conventional antiepileptic medication is associated with a reduction in the frequency of drop seizures among patients with Lennox-Gastaut syndrome, according to a study published in the May 17 issue of the New England Journal of Medicine.

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Nonprofit Manufacturer Could Keep Generic Drug Costs Down

WEDNESDAY, May 16, 2018 (HealthDay News) -- A nonprofit manufacturer could help keep generic drug prices down and maintain their supply, according to a perspective piece published in the May 17 issue of the New England Journal of Medicine.

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New Rabies Test Could Radically Change Testing, Treatment

WEDNESDAY, May 16, 2018 (HealthDay News) -- A new rapid rabies test for animals could revolutionize screening and spare humans unnecessary painful treatment, according to a U.S. Centers for Disease Control and Prevention study published online May 16 in PLOS ONE.

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Suicide Ideation, Attempts Increasing Among U.S. Children

WEDNESDAY, May 16, 2018 (HealthDay News) -- From 2008 to 2015 there was an increase in encounters for suicide ideation (SI) and suicide attempts (SAs) among U.S. children, according to a study published online May 16 in Pediatrics.

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Best Practices Developed for Use of EHR to Enhance Patient Care

WEDNESDAY, May 16, 2018 (HealthDay News) -- Best practices have been developed for using electronic health records (EHRs) to enhance patient-centered care, according to an article published online in Medical Economics.

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Sleep Apnea Rarely Investigated in Older Adults

WEDNESDAY, May 16, 2018 (HealthDay News) -- A high risk of obstructive sleep apnea (OSA) is common among older adults but is seldom investigated, though when it is investigated, it is almost always confirmed, according to a study published online May 9 in the Journal of the American Geriatrics Society.

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Fremanezumab Linked to Fewer Monthly Migraine Days

WEDNESDAY, May 16, 2018 (HealthDay News) -- For patients with episodic migraine, fremanezumab is associated with a reduction in the mean number of monthly migraine days, according to a study published in the May 15 issue of the Journal of the American Medical Association.

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Prevalence of Adult E-Cigarette Use Up from 2014 to 2016

TUESDAY, May 15, 2018 (HealthDay News) -- The prevalence of electronic cigarette (e-cigarette) ever use increased among U.S. adults from 2014 to 2016, according to a research letter published in the May 15 issue of the Journal of the American Medical Association.

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Shower Cream, Body Lotion Combo Improves Atopic Dry Skin

TUESDAY, May 15, 2018 (HealthDay News) -- A shower cream and a body lotion with physiological lipids are effective in improving skin hydration in patients with dry skin, according to a study published online May 10 in the Journal of Cosmetic Dermatology.

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Hyoscyamine Helps in A-Fib With Slow Ventricular Response

TUESDAY, May 15, 2018 (HealthDay News) -- Hyoscyamine can prevent pacemaker placement in a patient with symptoms caused by a slow ventricular response during atrial fibrillation, according to a case study published online May 15 in the Annals of Internal Medicine.

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High Occupational Exercise Level Tied to Early Mortality in Men

TUESDAY, May 15, 2018 (HealthDay News) -- High levels of occupational physical activity in men are associated with an increased risk of early mortality, according to a review published online May 14 in the British Journal of Sports Medicine.

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Asthma Mortality Inversely Tied to Deprivation in English Young

TUESDAY, May 15, 2018 (HealthDay News) -- For children and younger adults with asthma, prevalence and admissions increase with deprivation, while mortality is inversely associated with deprivation, according to a study published online May 14 in Thorax.

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Novel Purchasing Strategy Could Cut Medicaid Costs for HCV Meds

TUESDAY, May 15, 2018 (HealthDay News) -- A novel purchasing strategy could dramatically reduce the costs of medications for hepatitis C virus (HCV), according to an Ideas and Opinions piece published online May 15 in the Annals of Internal Medicine.

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Risk Models Help Select Ever Smokers for Lung CA Screening

MONDAY, May 14, 2018 (HealthDay News) -- Four lung cancer risk models perform best in selecting ever-smokers for screening, according to a study published online May 15 in the Annals of Internal Medicine.

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Opioid-Related Payments Linked to Increase in Opioid Rx

MONDAY, May 14, 2018 (HealthDay News) -- Receipt of opioid-related payments from industry in 2014 was associated with increased opioid prescribing in 2015, according to a research letter published online May 14 in JAMA Internal Medicine.

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Rates of Major Depression Up Among U.S. Insured, Esp. Youth

MONDAY, May 14, 2018 (HealthDay News) -- Diagnoses of major depression have increased since 2013, particularly among adolescents and millennials, according to a report published May 10 by Blue Cross Blue Shield (BCBS).

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Practice Intervention Targeting IV Opioids May Cut Exposure

MONDAY, May 13, 2018 (HealthDay News) -- An intervention targeting the use of intravenous opioids may reduce opioid exposure, according to a study published online May 14 in JAMA Internal Medicine.

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Primary Care Providers Have Mixed Views on Genetic Tests

FRIDAY, May 11, 2018 (HealthDay News) -- Primary care providers view tests for genetic risks of common diseases as useful, but lack confidence in interpreting results, according to a study published in the May issue of Health Affairs.

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Fx Risk Should Be Monitored in Bisphosphonate Drug Holiday

FRIDAY, May 11, 2018 (HealthDay News) -- For patients with osteopenia or osteoporosis, taking a bisphosphonate (BP) drug holiday is associated with increased risk of fracture for patients with lower femoral neck bone mineral density (BMD) or T scores, according to a recent study published in Endocrine Practice.

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Malnutrition Is Associated With Poor Prognosis in Heart Failure

FRIDAY, May 11, 2018 (HealthDay News) -- Patients with heart failure frequently have malnutrition, which is associated with increased mortality, according to a study published online May 9 in JACC: Heart Failure.

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Resistance Exercise May Reduce Depressive Symptoms in Adults

FRIDAY, May 11, 2018 (HealthDay News) -- Resistance exercise training (RET) is associated with reduced depressive symptoms among adults, according to a meta-analysis published online May 9 in JAMA Psychiatry.

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Novel Thirdhand Smoke Exposure Route Identified

THURSDAY, May 10, 2018 (HealthDay News) -- Thirdhand smoke (THS), the chemical residue from cigarette smoke that attaches to anything and anyone in the vicinity of a smoke cloud, can still make its way into the air of buildings that currently have a non-smoking designation, according to a study published online May 9 in Science Advances.

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FDA Targets Clinics Offering Unapproved Stem Cell Therapies

THURSDAY, May 10, 2018 (HealthDay News) -- The U.S. Food and Drug Administration has launched legal action to stop two stem cell clinics from providing unapproved treatments that have caused serious, long-term harm to some patients.

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Many Oncologists Discuss, Recommend Medical Marijuana

THURSDAY, May 10, 2018 (HealthDay News) -- Many oncologists recommend medical marijuana (MM) clinically despite not feeling sufficiently knowledgeable about its utility, according to a study published online May 10 in the Journal of Clinical Oncology.

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Gestational Diabetes May Indicate Future Subclinical Renal Issues

THURSDAY, May 10, 2018 (HealthDay News) -- Gestational diabetes mellitus (GDM) may be an early indicator of subsequent subclinical renal dysfunction, according to a study published online May 4 in Diabetes Care.

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Low-Dose Vaginal Estradiol Improves Menopause-Linked QOL

THURSDAY, May 10, 2018 (HealthDay News) -- For menopausal women with moderate-severe vulvovaginal symptoms, treatment with low-dose vaginal estradiol is associated with improved menopause-related quality of life, according to a study published online May 7 in Menopause.

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Age of First Football Tackles Tied to Neuro Symptom Onset

THURSDAY, May 10, 2018 (HealthDay News) -- Younger age of exposure to tackle football predicts earlier neurobehavioral symptom onset among players with chronic traumatic encephalopathy (CTE), according to a study published online April 30 in the Annals of Neurology.

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Lymphoma, Leukemia Survivors Have Increased Health Care Use

WEDNESDAY, May 9, 2018 (HealthDay News) -- Survivors of lymphoma and chronic lymphocytic leukemia (CLL) have increased use of health care services versus a normative population, according to a study published online April 26 in Cancer.

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Psychological Therapies May Help Older Adults With Chronic Pain

WEDNESDAY, May 9, 2018 (HealthDay News) -- For older adults with chronic pain, psychological interventions have small benefits, including reducing pain and catastrophizing beliefs, according to a review published online May 7 in JAMA Internal Medicine.

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Chronic Aspirin Exposure Linked to Melanoma Risk in Males

WEDNESDAY, May 9, 2018 (HealthDay News) -- Chronic acetylsalicylic acid (ASA; aspirin) exposure is associated with increased risk of malignant melanoma (MM) in men, but not women, according to a letter to the editor published online March 27 in the Journal of the American Academy of Dermatology.

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Surgery for Hip Fx Cuts Mortality in NH Residents With Dementia

WEDNESDAY, May 9, 2018 (HealthDay News) -- For nursing home (NH) residents with dementia and hip fracture, surgical hip fracture repair is associated with lower mortality, according to a study published online May 7 in JAMA Internal Medicine.

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Crowdfunding Exaggerates Efficacy of Unproven Stem Cell Tx

WEDNESDAY, May 9, 2018 (HealthDay News) -- Crowdfunding campaigns for unproven stem cell-based interventions tend to exaggerate the efficacy and underemphasize the risks, according to a research letter published in the May 8 issue of the Journal of the American Medical Association.

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Coaching to Up H2O Intake Does Not Slow eGFR Decline in CKD

WEDNESDAY, May 9, 2018 (HealthDay News) -- Coaching to increase water intake does not significantly slow the decline in kidney function among adults with chronic kidney disease, according to a study published in the May 8 issue of the Journal of the American Medical Association.

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Lesbian, Bi Women More Likely to Develop T2DM at Younger Age

WEDNESDAY, May 9, 2018 (HealthDay News) -- Lesbian and bisexual (LB) women are more likely to develop type 2 diabetes at a younger age than heterosexual women, with the difference mediated by body mass index (BMI), according to a study published online May 2 in Diabetes Care.

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Regulatory Requirements Drive Dissatisfaction With EHRs

TUESDAY, May 8, 2018 (HealthDay News) -- Regulatory requirements are likely to be an important aspect of physician dissatisfaction with electronic health records (EHRs) that is driving burnout, according to an Ideas and Opinions piece published online May 8 in the Annals of Internal Medicine.

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USPSTF: Decision to Undergo PSA Screening Should Be Individual

TUESDAY, May 8, 2018 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) concludes that the decision to undergo periodic prostate-specific antigen (PSA) screening for prostate cancer should be an individual one for men aged 55 to 69 years. These findings form the basis of a final recommendation statement, published in the May 8 issue of the Journal of the American Medical Association.

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Exceptional Glycemic Control With Very Low-Carbohydrate Diet

TUESDAY, May 8, 2018 (HealthDay News) -- For children and adults with type 1 diabetes mellitus (T1DM), consuming a very low-carbohydrate diet (VLCD) is associated with exceptional glycemic control, according to a study published online May 7 in Pediatrics.

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High Number of Years of Life Lost Due to Police Violence in U.S.

TUESDAY, May 8, 2018 (HealthDay News) -- The number of years of life lost (YLLs) due to police violence in the United States is substantial and disproportionately impacts young people of color, according to a study published online May 7 in the Journal of Epidemiology & Community Health.

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Long-Term Cardiovascular Risk for Endometrial Cancer Survivors

TUESDAY, May 8, 2018 (HealthDay News) -- Endometrial cancer survivors have an elevated risk of various adverse long-term cardiovascular outcomes, according to a study published online May 8 in the Journal of the National Cancer Institute.

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Approaches to Firearms for Persons With Dementia Discussed

TUESDAY, May 8, 2018 (HealthDay News) -- Approaches to addressing the potential complications of owning firearms for persons with dementia (PWD) are presented in an article published online May 8 in the Annals of Internal Medicine.

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Evidence Lacking for Impact of PDMPs on Drug Overdoses

TUESDAY, May 8, 2018 (HealthDay News) -- There is insufficient evidence available for examining the correlation between prescription drug monitoring programs (PDMPs) and non-fatal or fatal overdoses, according to a review published online May 8 in the Annals of Internal Medicine.

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Cancer Incidences and Burden Expected to Shift in HIV-Positive

MONDAY, May 7, 2018 (HealthDay News) -- The cancer burden among persons living with HIV (PLWH) is projected to shift by 2030, according to a study published online May 8 in the Annals of Internal Medicine.

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Folic Acid May Cut Stroke Risk in High-Risk Hypertensive Patients

MONDAY, May 7, 2018 (HealthDay News) -- Hypertensive patients may lower their stroke risk with folic acid supplements, according to a study published in the May 15 issue of the Journal of the American College of Cardiology.

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Psoriasis Negatively Affects Patient Sleep Quality

MONDAY, May 7, 2018 (HealthDay News) -- Patients with psoriasis commonly report poor sleep, with itch being the main predictor, according to a study published online April 28 in the British Journal of Dermatology.

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Provider Counseling for Weight Loss Up for Arthritis, Overweight

MONDAY, May 7, 2018 (HealthDay News) -- In 2014, health care provider counseling for weight loss for adults with arthritis and overweight or obesity was 45.5 percent, up 10.4 percent from 2002, according to research published in the May 3 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Pharmacists Can Play Role in Identifying Frailty

FRIDAY, May 4, 2018 (HealthDay News) -- As the number of older people in the United States continues to increase, pharmacists and health care professionals need to recognize and address the health care challenges associated with age, including frailty, according to an article published in Drug Topics.

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Many Organizations Not Meeting Trial Reporting Requirements

FRIDAY, May 4, 2018 (HealthDay News) -- Many organizations are not meeting the trial registration and results reporting requirements clarified by "The Final Rule," which had a compliance date of April 18, 2017, according to a study published online May 1 in BMC Medicine.

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Study IDs Pain Descriptors for Varying Stages of Low Back Pain

FRIDAY, May 4, 2018 (HealthDay News) -- Varying pain descriptors may be useful when evaluating patients with different stages of low back pain (LBP), according to a study published online April 30 in PAIN Practice.

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Physical Therapy Helps Recover Arm Function in Chronic CVA

FRIDAY, May 4, 2018 (HealthDay News) -- Physical therapy promotes the recovery of arm function and neuroplasticity in all chronic stroke patients, according to a study published online April 25 in the Journal of Evaluation in Clinical Practice.

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Five Strategies to Reduce Acute Care for Cancer Patients ID'd

THURSDAY, May 3, 2018 (HealthDay News) -- Five major strategies exist for reducing acute care for patients with cancer, according to a review published online April 17 in the Journal of Oncology Practice.

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Midlife Transition Tied to Decreasing Stress in Women

THURSDAY, May 3, 2018 (HealthDay News) -- Self-reported stress decreases for most women as they transition through midlife, according to a recent study published in Women's Midlife Health.

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Sleep Duration Linked to Health-Related QoL in Kidney Disease

THURSDAY, May 3, 2018 (HealthDay News) -- Sleep duration is associated with health-related quality of life among patients with chronic kidney disease (CKD), according to a study published online May 3 in the Clinical Journal of the American Society of Nephrology.

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Systemic Inflammation at Midlife May Up Risk of Later Frailty

THURSDAY, May 3, 2018 (HealthDay News) -- Those with systemic inflammation during midlife are more likely to have age-related frailty, according to a recent study published in The Journals of Gerontology: Series A.

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Older Adults Agree Sex Is Important Part of Relationships

THURSDAY, May 3, 2018 (HealthDay News) -- Most older adults agree that sex is an important part of a romantic relationship at any age, according to the National Poll on Healthy Aging.

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Health Care for Undocumented Immigrants Is Complex

WEDNESDAY, May 2, 2018 (HealthDay News) -- In a perspective piece published in the May 2 issue of the New England Journal of Medicine, health care for undocumented immigrants is addressed in the context of an anti-immigration federal policy environment.

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Vectorborne Diseases Up More Than Two-Fold From 2004 to 2016

WEDNESDAY, May 2, 2018 (HealthDay News) -- Vectorborne diseases represent an increasing problem in the United States, with a more than two-fold increase in the number of annual reports from 2004 to 2016, according to research published in the May 1 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Palliative Care Consult Can Cut Hospital Costs in Seriously Ill

WEDNESDAY, May 2, 2018 (HealthDay News) -- For hospitalized adults with serious illness, receiving a palliative care consultation (PCC) is associated with a reduction in hospital costs, according to a review published online April 30 in JAMA Internal Medicine.

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In Heart Failure, Initial ICU Care by Cardiologist Differs by Race

WEDNESDAY, May 2, 2018 (HealthDay News) -- Among heart failure patients admitted to the intensive care unit (ICU), African-Americans are less likely than Caucasians to receive primary care by a cardiologist, according to a study published in the May 1 issue of JACC: Heart Failure.

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Doctors Generally Confident With Deprescribing for Elderly

TUESDAY, May 1, 2018 (HealthDay News) -- Physicians are generally comfortable with deprescribing for elderly patients, although there are several barriers to deprescribing, according to a study published online April 22 in the Journal of Clinical Pharmacy and Therapeutics.

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Knowledge of Causes of Cancer Low in General Population

TUESDAY, May 1, 2018 (HealthDay News) -- Among the general population, awareness of actual and mythical causes of cancer is poor, according to a study published online April 25 in the European Journal of Cancer.

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Practices Should Be Aware of Correct Way to Fire Employees

TUESDAY, May 1, 2018 (HealthDay News) -- Physicians should be aware of the correct protocol for, as well as the laws involved in, firing employees, according to a report published in Medical Economics.

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Metabolically Healthy Obesity Not Without Risk of CVD

TUESDAY, May 1, 2018 (HealthDay News) -- Metabolically healthy obesity (MHO) is not a stable or reliable indicator of future cardiovascular disease (CVD) risk, according to a study published in the May 1 issue of the Journal of the American College of Cardiology.

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Severe Obesity Tied to Faster Progression to Disability With RA

TUESDAY, May 1, 2018 (HealthDay News) -- Severe obesity is associated with more rapid progression of disability in patients with rheumatoid arthritis (RA), according to a study published online April 30 in Arthritis Care & Research.

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Certain Foods May Impact Timing of Menopause

TUESDAY, May 1, 2018 (HealthDay News) -- Intake of some food groups and nutrients may affect the timing of menopause, according to a study published online April 30 in the Journal of Epidemiology & Community Health.

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Early Readmissions More Preventable Than Later Ones

TUESDAY, May 1, 2018 (HealthDay News) -- Early general medicine readmissions are more likely than late readmissions to be preventable with hospital-based interventions, according to a study published online May 1 in the Annals of Internal of Medicine.

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