May 2018 Briefing - Gastroenterology

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Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for May 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

ASHP: SVP, Injectable Opioid Shortages Threaten Patient Care

THURSDAY, May 31, 2018 (HealthDay News) -- The widespread shortages of injectable opioids and small-volume parenteral (SVP) solutions are jeopardizing patient care and placing a strain on hospital operations, according to a report published by the American Society of Health-System Pharmacists (ASHP).

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FDA Approves New Treatment for Ulcerative Colitis

WEDNESDAY, May 30, 2018 (HealthDay News) -- U.S. Food and Drug Administration approval of Xeljanz (tofacitinib) has been expanded to include adults with active moderate-to-severe ulcerative colitis, the agency said Wednesday.

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ACS Updates Colorectal Cancer Screening to Start at Age 45

WEDNESDAY, May 30, 2018 (HealthDay News) -- Colorectal cancer (CRC) screening should begin at age 45 for people at average risk, according to updated guidelines from the American Cancer Society published online May 30 in CA: A Cancer Journal for Clinicians.

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Worse Survival for BRCA Germline Mutation Carriers in Pancreatic CA

WEDNESDAY, May 30, 2018 (HealthDay News) -- BRCA1/BRCA2 germline mutation carriers with pancreatic ductal adenocarcinoma (PDAC) have worse survival after resection, according to a study published in the April issue of the Journal of the American College of Surgeons.

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CDC IDs Outbreak Trends Tied to Treated Recreational Water

FRIDAY, May 25, 2018 (HealthDay News) -- Outbreaks associated with treated recreational water with confirmed infectious etiology are usually caused by Cryptosporidium, Legionella, or Pseudomonas, according to research published in the May 18 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Congress Approves Bill Expanding Private Care for VA Patients

THURSDAY, May 24, 2018 (HealthDay News) -- Patients served by the beleaguered Veterans Affairs health system may have wider access to private care, thanks to a bill approved Wednesday by the Senate. President Donald Trump is known to support the bill, which now awaits his signature.

AMA Statement
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Ingestible Bio-Electronic Device Could Monitor GI Health

THURSDAY, May 24, 2018 (HealthDay News) -- An ingestible micro-bio-electronic device (IMBED) could be used for in situ biomolecular detection based on environmentally resilient biosensor bacteria and luminescence readout electronics, according to a study published in the May 25 issue of Science.

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Global Variation in Personal Health Care Access and Quality

THURSDAY, May 24, 2018 (HealthDay News) -- There is considerable global variation in personal health care access and quality, according to a study published online May 23 in The Lancet.

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Editorial

Surveillance Frequency Doesn't Cut Mortality in Colorectal Cancer

TUESDAY, May 22, 2018 (HealthDay News) -- For patients with colorectal cancer after curative surgery, the frequency of surveillance is not associated with mortality; and, the intensity of posttreatment surveillance is not associated with detection of recurrence, according to two studies published in the May 22/29 issue of the Journal of the American Medical Association.

Abstract/Full Text - Wille-Jørgensen
Abstract/Full Text - Snyder
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CDC: No Change in Level of Uninsured in U.S. in 2017

TUESDAY, May 22, 2018 (HealthDay News) -- Overall, 9.1 percent of individuals in the United States were uninsured in 2017, which was not significantly different from the level in 2016, according to a report published online May 22 by the U.S. Centers for Disease Control and Prevention's National Centers for Health Statistics.

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IBD Associated With Increased Risk of Parkinson's Disease

TUESDAY, May 22, 2018 (HealthDay News) -- There is a significantly increased risk of Parkinson's disease (PD) in patients with inflammatory bowel disease (IBD), according to a study published online May 21 in Gut.

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FDA OKs Doptelet for Liver Dz Patients Undergoing Procedures

MONDAY, May 21, 2018 (HealthDay News) -- Doptelet (avatrombopag) has been approved by the U.S. Food and Drug Administration to treat adults with chronic liver disease who are slated to have a medical or dental procedure.

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Semaglutide Found to Be Effective Against Type 2 Diabetes

MONDAY, May 21, 2018 (HealthDay News) -- Semaglutide is safe and effective for the treatment of type 2 diabetes, according to a review published online May 13 in Diabetes, Obesity and Metabolism.

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Language Used in Medical Record Can Affect Patient Care

FRIDAY, May 18, 2018 (HealthDay News) -- Stigmatizing language used in medical records to describe patients can influence medical students and residents in terms of their attitudes towards the patient and their clinical decision-making, according to a study published in the May issue of the Journal of General Internal Medicine.

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V600E BRAF Mutation Tied to Worse Survival in CRC Liver Mets

FRIDAY, May 18, 2018 (HealthDay News) -- For patients undergoing resection of colorectal liver metastases (CRLM), the presence of the V600E BRAF mutation is associated with worse prognosis, according to a study published online May 16 in JAMA Surgery.

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Molecular Basis for Varied Presentations of ETEC Explored

FRIDAY, May 18, 2018 (HealthDay News) -- The EtpA adhesion molecule, which is secreted by enterotoxigenic Escherichia coli (ETEC) strain H10407, is a dominant ETEC blood group A-specific lectin/hemagglutinin, according to a study published online May 17 in the Journal of Clinical Investigation.

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Breath Test Shows Promise for Diagnosis of Esophagogastric CA

FRIDAY, May 18, 2018 (HealthDay News) -- Breath analysis shows potential for noninvasive diagnosis of esophagogastric cancer (OGC), according to a study published online May 17 in JAMA Oncology.

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Nonprofit Manufacturer Could Keep Generic Drug Costs Down

WEDNESDAY, May 16, 2018 (HealthDay News) -- A nonprofit manufacturer could help keep generic drug prices down and maintain their supply, according to a perspective piece published in the May 17 issue of the New England Journal of Medicine.

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Higher CRC Risk With Advanced Adenoma Found on Colonoscopy

WEDNESDAY, May 16, 2018 (HealthDay News) -- Participants with an advanced adenoma at diagnostic colonoscopy have increased risk of developing colorectal cancer (CRC) relative to those with no adenoma, according to a study published in the May 15 issue of the Journal of the American Medical Association.

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Hepatitis C-Exposed Infants Not Adequately Screened

WEDNESDAY, May 16, 2018 (HealthDay News) -- Many infants who are exposed to hepatitis C virus (HCV) during pregnancy are not screened for HCV infection, according to a study published online May 2 in Pediatrics.

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Best Practices Developed for Use of EHR to Enhance Patient Care

WEDNESDAY, May 16, 2018 (HealthDay News) -- Best practices have been developed for using electronic health records (EHRs) to enhance patient-centered care, according to an article published online in Medical Economics.

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Novel Purchasing Strategy Could Cut Medicaid Costs for HCV Meds

TUESDAY, May 15, 2018 (HealthDay News) -- A novel purchasing strategy could dramatically reduce the costs of medications for hepatitis C virus (HCV), according to an Ideas and Opinions piece published online May 15 in the Annals of Internal Medicine.

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Sofosbuvir Improves Renal Safety in Patients With Chronic Hep C

FRIDAY, May 11, 2018 (HealthDay News) -- Sofosbuvir-based treatment appears to guarantee renal safety for patients with chronic hepatitis C virus over one year of follow-up, according to a study published online May 7 in the Journal of Clinical Pharmacy and Therapeutics.

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FDA Permits Marketing of New Device for Treating GI Bleeding

TUESDAY, May 8, 2018 (HealthDay News) -- The U.S. Food and Drug Administration has approved the new Hemospray device to help control bleeding of the gastrointestinal (GI) tract.

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Regulatory Requirements Drive Dissatisfaction With EHRs

TUESDAY, May 8, 2018 (HealthDay News) -- Regulatory requirements are likely to be an important aspect of physician dissatisfaction with electronic health records (EHRs) that is driving burnout, according to an Ideas and Opinions piece published online May 8 in the Annals of Internal Medicine.

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Many Organizations Not Meeting Trial Reporting Requirements

FRIDAY, May 4, 2018 (HealthDay News) -- Many organizations are not meeting the trial registration and results reporting requirements clarified by "The Final Rule," which had a compliance date of April 18, 2017, according to a study published online May 1 in BMC Medicine.

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Gender Disparity Observed in Cancer Genetic Testing in the U.S.

THURSDAY, May 3, 2018 (HealthDay News) -- Specific demographic groups have lower cancer genetic testing, including unaffected men compared with unaffected women, according to a research letter published online April 26 in JAMA Oncology.

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Reporting Outcomes Per Surgeon Tied to Drop in CRC Sx Mortality

THURSDAY, May 3, 2018 (HealthDay News) -- The introduction of public reporting of surgeon specific 90-day postoperative mortality in elective colorectal cancer surgery is associated with a reduction in observed 90-day mortality, according to a study published online May 2 in The BMJ.

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Nodal Response to Pre-Op Tx Tied to Survival in Esophageal Cancer

WEDNESDAY, May 2, 2018 (HealthDay News) -- For patients with locally advanced esophageal cancer, the status of lymph nodes following preoperative neoadjuvant chemotherapy or chemoradiation therapy determines survival, according to a study presented at the annual meeting of the American Association for Thoracic Surgery, held from April 28 to May 1 in San Diego.

Abstract
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Practices Should Be Aware of Correct Way to Fire Employees

TUESDAY, May 1, 2018 (HealthDay News) -- Physicians should be aware of the correct protocol for, as well as the laws involved in, firing employees, according to a report published in Medical Economics.

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