May 2018 Briefing - Diabetes & Endocrinology

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for May 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

ASHP: SVP, Injectable Opioid Shortages Threaten Patient Care

THURSDAY, May 31, 2018 (HealthDay News) -- The widespread shortages of injectable opioids and small-volume parenteral (SVP) solutions are jeopardizing patient care and placing a strain on hospital operations, according to a report published by the American Society of Health-System Pharmacists (ASHP).

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CVD Risk Up Even in Metabolically Healthy Obese Women

THURSDAY, May 31, 2018 (HealthDay News) -- Obesity is associated with increased risk of cardiovascular disease risk even among metabolically healthy women, according to a study published online May 30 in The Lancet Diabetes & Endocrinology.

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T1DM Self-Management Varies With Adult Developmental Stages

THURSDAY, May 31, 2018 (HealthDay News) -- Type 1 diabetes self-management behaviors vary across adult developmental stages, according to a study published online May 25 in Diabetes Care.

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Elevated HbA1c Usually Leads to Prompt Tx Start, Intensification

WEDNESDAY, May 30, 2018 (HealthDay News) -- Most patients are newly initiated on antidiabetic therapy or have antidiabetic therapy intensified within six months of hemoglobin A1c (HbA1c) elevation, according to a study published online May 24 in Diabetes Care.

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Senior CA Patients Also Benefit From Palliative Radiotherapy

WEDNESDAY, May 30, 2018 (HealthDay News) -- All patients with painful bone metastasis should be referred for palliative radiotherapy to relieve the pain, regardless of age, according to a study published online May 23 in the Journal of Medical Imaging and Radiation Oncology.

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Hypofractionated Radiotherapy Best in Anaplastic Thyroid Cancer

TUESDAY, May 29, 2018 (HealthDay News) -- In an orthotopic anaplastic thyroid cancer (ATC) model, hypofractionated radiotherapy (RT) is superior to conventionally fractionated RT, according to a study published online May 18 in Thyroid.

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Mini-Dose Glucagon May Halt Post-Exercise Hypoglycemia

TUESDAY, May 29, 2018 (HealthDay News) -- Mini-dose glucagon (MDG) is an effective approach for preventing exercise-induced hypoglycemia in patients with type 1 diabetes, according to a study published online May 18 in Diabetes Care.

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Non-Nutritive Sweeteners Don't Up Blood Glucose Levels

FRIDAY, May 25, 2018 (HealthDay News) -- Consumption of non-nutritive sweeteners (NNSs) does not increase blood glucose levels, according to a review published online May 15 in the European Journal of Clinical Nutrition.

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Higher Seafood Intake May Shorten Time to Pregnancy

FRIDAY, May 25, 2018 (HealthDay News) -- Higher seafood intake is tied to a shorter time to pregnancy (TTP), according to a study published online May 23 in the Journal of Clinical Endocrinology & Metabolism.

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Congress Approves Bill Expanding Private Care for VA Patients

THURSDAY, May 24, 2018 (HealthDay News) -- Patients served by the beleaguered Veterans Affairs health system may have wider access to private care, thanks to a bill approved Wednesday by the Senate. President Donald Trump is known to support the bill, which now awaits his signature.

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Burosumab May Benefit Children With X-Linked Hypophosphatemia

THURSDAY, May 24, 2018 (HealthDay News) -- For children with X-linked hypophosphatemia, subcutaneous burosumab is associated with decreases in rickets severity and with improved renal tubular phosphate reabsorption, according to a study published in the May 24 issue of the New England Journal of Medicine.

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Atherosclerotic CVD Mortality Higher in South Asians in the U.S.

THURSDAY, May 24, 2018 (HealthDay News) -- South Asians in the United States have increased proportional mortality rates from atherosclerotic cardiovascular disease (ASCVD), although there are no unique risk factors in this population, according to a scientific statement from the American Heart Association published online May 24 in Circulation.

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Global Variation in Personal Health Care Access and Quality

THURSDAY, May 24, 2018 (HealthDay News) -- There is considerable global variation in personal health care access and quality, according to a study published online May 23 in The Lancet.

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Major Depression in Males May Lower Chances of Conception

THURSDAY, May 24, 2018 (HealthDay News) -- Active major depression (MD) in the male partner may lower the likelihood of pregnancy, according to a study published in the May issue of Fertility & Sterility.

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Inverse Link for Plasma 25(OH)D Concentration, Risk of T2DM

WEDNESDAY, May 23, 2018 (HealthDay News) -- There is an inverse association for plasma 25-hydroxyvitamin D (25[OH]D) concentration with diabetes risk, according to a study published online April 19 in PLOS ONE.

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Vitamin D Supplement Tied to Less Wheezing in Black Preemies

WEDNESDAY, May 23, 2018 (HealthDay News) -- Vitamin D sustained supplementation is associated with reduced recurrent wheezing among black infants born preterm, according to a study published in the May 22/29 issue of the Journal of the American Medical Association.

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CDC: No Change in Level of Uninsured in U.S. in 2017

TUESDAY, May 22, 2018 (HealthDay News) -- Overall, 9.1 percent of individuals in the United States were uninsured in 2017, which was not significantly different from the level in 2016, according to a report published online May 22 by the U.S. Centers for Disease Control and Prevention's National Centers for Health Statistics.

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Moral Distress for Docs Providing Emergency-Only Hemodialysis

TUESDAY, May 22, 2018 (HealthDay News) -- Clinicians who provide emergency-only hemodialysis (EOHD) to undocumented immigrants experience moral distress and professional burnout, according to a study published online May 22 in the Annals of Internal Medicine.

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2003 to 2014 Saw Rise in Diabetic Ketoacidosis Admissions

TUESDAY, May 22, 2018 (HealthDay News) -- The incidence of hospitalization for diabetic ketoacidosis (DKA) and associated costs increased from 2003 to 2014, according to a study published online May 17 in Diabetes Care.

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Semaglutide Found to Be Effective Against Type 2 Diabetes

MONDAY, May 21, 2018 (HealthDay News) -- Semaglutide is safe and effective for the treatment of type 2 diabetes, according to a review published online May 13 in Diabetes, Obesity and Metabolism.

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Language Used in Medical Record Can Affect Patient Care

FRIDAY, May 18, 2018 (HealthDay News) -- Stigmatizing language used in medical records to describe patients can influence medical students and residents in terms of their attitudes towards the patient and their clinical decision-making, according to a study published in the May issue of the Journal of General Internal Medicine.

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Pharmacists Should Counsel Patients Fasting for Ramadan

FRIDAY, May 18, 2018 (HealthDay News) -- Pharmacists should counsel Muslim patients who fast during Ramadan with respect to their medications and adjusting their medication regimen, according to an article published in Drug Topics.

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Chemicals in Hair Products for Black Women Raise Concerns

FRIDAY, May 18, 2018 (HealthDay News) -- Multiple chemicals associated with endocrine disruption and asthma are contained in hair products used by black women and children, according to a study published online April 25 in Environmental Research.

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Higher Adiposity Increases Odds of Smoking

FRIDAY, May 18, 2018 (HealthDay News) -- Obesity is linked to an increased risk of smoking and an increase in the number of cigarettes smoked daily, according to a study published online May 16 in The BMJ.

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U.S. Nursing Home Costs Due to Diabetes Vary Greatly by State

THURSDAY, May 17, 2018 (HealthDay News) -- Diabetes-attributable nursing home costs are substantial, but vary greatly across the nation, according to a study published online May 14 in Diabetes Care.

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Nonprofit Manufacturer Could Keep Generic Drug Costs Down

WEDNESDAY, May 16, 2018 (HealthDay News) -- A nonprofit manufacturer could help keep generic drug prices down and maintain their supply, according to a perspective piece published in the May 17 issue of the New England Journal of Medicine.

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Best Practices Developed for Use of EHR to Enhance Patient Care

WEDNESDAY, May 16, 2018 (HealthDay News) -- Best practices have been developed for using electronic health records (EHRs) to enhance patient-centered care, according to an article published online in Medical Economics.

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Dual-Hormone System May Lower Time in Hypoglycemia in T1DM

TUESDAY, May 15, 2018 (HealthDay News) -- For physically active adults with type 1 diabetes, the addition of glucagon delivery to a closed-loop system using wearable sensors with automated exercise detection is associated with reduced hypoglycemia, according to a study published online May 11 in Diabetes Care.

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Fx Risk Should Be Monitored in Bisphosphonate Drug Holiday

FRIDAY, May 11, 2018 (HealthDay News) -- For patients with osteopenia or osteoporosis, taking a bisphosphonate (BP) drug holiday is associated with increased risk of fracture for patients with lower femoral neck bone mineral density (BMD) or T scores, according to a recent study published in Endocrine Practice.

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FDA Targets Clinics Offering Unapproved Stem Cell Therapies

THURSDAY, May 10, 2018 (HealthDay News) -- The U.S. Food and Drug Administration has launched legal action to stop two stem cell clinics from providing unapproved treatments that have caused serious, long-term harm to some patients.

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Gestational Diabetes May Indicate Future Subclinical Renal Issues

THURSDAY, May 10, 2018 (HealthDay News) -- Gestational diabetes mellitus (GDM) may be an early indicator of subsequent subclinical renal dysfunction, according to a study published online May 4 in Diabetes Care.

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Lesbian, Bi Women More Likely to Develop T2DM at Younger Age

WEDNESDAY, May 9, 2018 (HealthDay News) -- Lesbian and bisexual (LB) women are more likely to develop type 2 diabetes at a younger age than heterosexual women, with the difference mediated by body mass index (BMI), according to a study published online May 2 in Diabetes Care.

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Regulatory Requirements Drive Dissatisfaction With EHRs

TUESDAY, May 8, 2018 (HealthDay News) -- Regulatory requirements are likely to be an important aspect of physician dissatisfaction with electronic health records (EHRs) that is driving burnout, according to an Ideas and Opinions piece published online May 8 in the Annals of Internal Medicine.

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Exceptional Glycemic Control With Very Low-Carbohydrate Diet

TUESDAY, May 8, 2018 (HealthDay News) -- For children and adults with type 1 diabetes mellitus (T1DM), consuming a very low-carbohydrate diet (VLCD) is associated with exceptional glycemic control, according to a study published online May 7 in Pediatrics.

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Type 2 Diabetes Ups Risk of Renal Cancer in Women, but Not Men

TUESDAY, May 8, 2018 (HealthDay News) -- Type 2 diabetes is independently associated with a greater risk of renal cell carcinoma (RCC) in women, but not in men, according to a study published online April 20 in Diabetes Care.

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FDA Approves Drug Combo for Aggressive Thyroid Cancer

MONDAY, May 7, 2018 (HealthDay News) -- Two anti-cancer drugs administered together have been approved by the U.S. Food and Drug Administration to treat BRAF-positive anaplastic thyroid cancer.

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Daily Sports Drink Consumption Down in U.S. Teenagers

MONDAY, May 7, 2018 (HealthDay News) -- Teenagers' weekly consumption of sports drinks increased from 2010 to 2015, although daily consumption declined for most teens, according to a study published online May 7 in Pediatrics.

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Community Health Worker-Led Intervention Beneficial in T2DM

MONDAY, May 7, 2018 (HealthDay News) -- A community health worker (CHW)-led diabetes self-management education (DSME) program is associated with sustained improvement in hemoglobin A1c (HbA1c), according to a study published online April 27 in Diabetes Care.

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Many Organizations Not Meeting Trial Reporting Requirements

FRIDAY, May 4, 2018 (HealthDay News) -- Many organizations are not meeting the trial registration and results reporting requirements clarified by "The Final Rule," which had a compliance date of April 18, 2017, according to a study published online May 1 in BMC Medicine.

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Novel Signal ID'd for Microalbuminuria in Europeans With T2DM

FRIDAY, May 4, 2018 (HealthDay News) -- A novel signal has been identified that is associated with microalbuminuria in Europeans with type 2 diabetes (T2D), according to a study published online April 27 in Diabetes.

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Reproductive Markers Associated With Risk of Diabetes

THURSDAY, May 3, 2018 (HealthDay News) -- Markers of reproductive history, including age of menarche and parity, may be tied to future diabetes risk in women with a body mass index (BMI) ≥25 kg/m², according to a study published in Diabetes, Obesity and Metabolism.

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Practices Should Be Aware of Correct Way to Fire Employees

TUESDAY, May 1, 2018 (HealthDay News) -- Physicians should be aware of the correct protocol for, as well as the laws involved in, firing employees, according to a report published in Medical Economics.

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Glyburide Not Noninferior to Insulin for Gestational Diabetes

TUESDAY, May 1, 2018 (HealthDay News) -- For women with gestational diabetes, glyburide is not noninferior to insulin, according to a study published in the May 1 issue of the Journal of the American Medical Association.

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Metabolically Healthy Obesity Not Without Risk of CVD

TUESDAY, May 1, 2018 (HealthDay News) -- Metabolically healthy obesity (MHO) is not a stable or reliable indicator of future cardiovascular disease (CVD) risk, according to a study published in the May 1 issue of the Journal of the American College of Cardiology.

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Perioperative MACCEs More Common With Diabetes

TUESDAY, May 1, 2018 (HealthDay News) -- Perioperative major adverse cardiovascular and cerebrovascular events (MACCEs) are more common among patients with diabetes mellitus (DM), according to a study published online April 4 in Diabetes Care.

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