March 2018 Briefing - Diabetes & Endocrinology

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for March 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Lower Energy Consumption for South Asian Migrants With T2DM

FRIDAY, March 30, 2018 (HealthDay News) -- Among South Asian (SA) migrants in the United States, those with type 2 diabetes mellitus (T2DM) consume less total energy and have lower consumption of many nutrients than those without T2DM, according to a study published in the April issue of Diabetes Research and Clinical Practice.

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Dining Out Linked to Phthalates Exposure in U.S. Population

THURSDAY, March 29, 2018 (HealthDay News) -- Among the U.S. population, dining out is associated with exposure to phthalates, according to a study published online March 28 in Environment International.

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Islet Transplantation Improves Quality of Life in T1DM

THURSDAY, March 29, 2018 (HealthDay News) -- There are significant improvements in health-related quality of life (HRQOL) following islet transplantation in patients with type 1 diabetes complicated by severe hypoglycemia, according to a study published online March 21 in Diabetes Care.

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Novel Interstitium Has Been Identified in Human Tissues

THURSDAY, March 29, 2018 (HealthDay News) -- A previously unrecognized interstitium has been identified in human tissues, according to a study published online March 27 in Scientific Reports.

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Menopausal Hormone Therapy Linked to Reduced Abdominal Fat

WEDNESDAY, March 28, 2018 (HealthDay News) -- Women who receive menopausal hormone therapy (MHT) have reduced age-adjusted visceral adipose tissue (VAT), according to a study published online March 27 in the Journal of Clinical Endocrinology & Metabolism.

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Use of E-Cigarettes May Hurt Efforts to Quit Smoking

WEDNESDAY, March 28, 2018 (HealthDay News) -- Among smokers who plan to quit after being discharged from the hospital, electronic cigarette (e-cigarette) users are less likely to abstain from tobacco at six months, compared to nonusers, according to a study published online March 27 in the Annals of Internal Medicine.

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Recent Years Have Seen Obesity Prevalence Increasing for Adults

WEDNESDAY, March 28, 2018 (HealthDay News) -- For adults, but not youth, there was an increase in the prevalence of obesity in decade between 2007-2008 and 2015-2016, according to a research letter published online March 23 in the Journal of the American Medical Association.

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Total Estimated Cost of Diagnosed Diabetes $327 Billion in 2017

WEDNESDAY, March 28, 2018 (HealthDay News) -- The total estimated cost of diagnosed diabetes in 2017 was $327 billion, including $237 billion in direct medical costs, according to a study published online March 22 in Diabetes Care.

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EHR Usability Contributes to Possible Patient Harm Events

TUESDAY, March 27, 2018 (HealthDay News) -- Electronic health record (EHR) usability may contribute to possible patient harm events, according to a research letter published in the March 27 issue of the Journal of the American Medical Association.

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Complete Genome Sequence Can Be ID'd From Amniotic Fluid

TUESDAY, March 27, 2018 (HealthDay News) -- The complete genome sequence of fetuses can be elucidated from amniotic fluid, according to a study published online March 15 in Clinical Chemistry.

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Ethical Duties ID'd for Short-Term Global Health Experiences

MONDAY, March 26, 2018 (HealthDay News) -- In a position paper published online March 27 in the Annals of Internal Medicine, ethical obligations have been detailed for physicians participating in short-term global health experiences (STEGHs).

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Intensive Lifestyle Interventions Cut Long-Term Disability in T2DM

MONDAY, March 26, 2018 (HealthDay News) -- For overweight or obese adults with type 2 diabetes, a long-term weight loss intervention is associated with a reduction in long-term disability, according to a study published online March 15 in Diabetes Care.

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Sports Sponsorships Often Market Unhealthy Food and Drinks

MONDAY, March 26, 2018 (HealthDay News) -- Sports sponsorships frequently advertise unhealthy food and nonalcoholic beverages, according to a study published online March 26 in Pediatrics.

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Only Half of Adults With Familial Hypercholesterolemia on Statins

MONDAY, March 26, 2018 (HealthDay News) -- Only about 50 percent of adults with familial hypercholesterolemia (FH) are on statin therapy, and approximately 30 percent of those are taking high-intensity statins, according to a study published online March 26 in Circulation.

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Lean Approach May Help Tackle Burnout in Health Care Providers

FRIDAY, March 23, 2018 (HealthDay News) -- The Lean approach, which emphasizes reducing waste and improving customer value by focusing on the big picture, can be used to address physician burnout, according to a report published in Medical Economics.

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MVPA Mortality Risk Reduction Not Tied to Exercise in Bouts

FRIDAY, March 23, 2018 (HealthDay News) -- Moderate-to-vigorous physical activity (MVPA) is associated with reduced mortality risk, regardless of whether it is accumulated in bouts, according to a study published online March 22 in the Journal of the American Heart Association.

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Food Insecurity Tied to Poor Glycemic Control in Diabetes

FRIDAY, March 23, 2018 (HealthDay News) -- Limited food access owing to cost (food insecurity) is associated with increased hemoglobin A1c (HbA1C) among patients with diabetes, according to a study published online March 19 in Diabetes Care.

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Unique Risks Associated With Texting Medical Orders

THURSDAY, March 22, 2018 (HealthDay News) -- Despite the popularity, convenience, and speed of texting medical orders, there are unique and alarming risks associated with the practice, according to a report published in Drug Topics.

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Calorie Restriction Linked to Sustained Metabolic Adaptation

THURSDAY, March 22, 2018 (HealthDay News) -- Calorie restriction (CR) over two years is associated with considerable weight loss, and with lower than expected energy expenditure (EE) relative to the weight loss, according to a study published online March 22 in Cell Metabolism.

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Dipeptidyl Peptidase-4 Inhibitors in T2DM Linked to IBD

THURSDAY, March 22, 2018 (HealthDay News) -- Dipeptidyl peptidase-4 (DPP-4) inhibitors are associated with increased risk of inflammatory bowel disease among patients with type 2 diabetes, according to a study published online March 21 in The BMJ.

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Soy-Based Formula Tied to Reproductive Differences

THURSDAY, March 22, 2018 (HealthDay News) -- Infants given soy-based formula have reproductive system differences compared with those given cow-milk formula or breast milk, according to a study published online March 1 in the Journal of Clinical Endocrinology & Metabolism.

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Oxyntomodulin Augments Glucose Homeostasis

WEDNESDAY, March 21, 2018 (HealthDay News) -- In obese subjects with and without type 2 diabetes mellitus (T2DM), oxyntomodulin (OXM) significantly augments glucose-dependent insulin secretion, according to a study published online March 15 in Diabetes.

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Blueprint Being Developed to Address Physician Burnout

WEDNESDAY, March 21, 2018 (HealthDay News) -- A new, three-pronged approach is being applied to develop a blueprint for addressing physician burnout, according to a report published in Medical Economics.

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Personal Health Info Found in Recycling at Five Hospitals

TUESDAY, March 20, 2018 (HealthDay News) -- A considerable amount of personal health information (PHI) and personally identifiable information (PII) was found in the recycling at five Canadian teaching hospitals, according to a research letter published in the March 20 issue of the Journal of the American Medical Association.

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High Intake of Red Meats Tied to Liver Disease, Insulin Resistance

TUESDAY, March 20, 2018 (HealthDay News) -- High consumption of red and/or processed meat is associated with nonalcoholic fatty liver disease (NAFLD) and insulin resistance (IR), according to a study published online March 20 in the Journal of Hepatology.

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Prior Authorization Negatively Impacts Clinical Outcomes

MONDAY, March 19, 2018 (HealthDay News) -- The burdens associated with prior authorization (PA) are high and include a negative impact on clinical outcomes, reported by 92 percent of physicians, according to the results of a survey conducted for the American Medical Association (AMA).

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Altered Neural Responses in Memory Processing in T1DM

MONDAY, March 19, 2018 (HealthDay News) -- Young adults with type 1 diabetes have altered neural responses during working memory processing, according to a study published online March 12 in Diabetes.

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Closed-Loop Insulin Delivery Promising in T1DM Pregnancy

FRIDAY, March 16, 2018 (HealthDay News) -- For pregnant women with type 1 diabetes, a closed-loop system is associated with comparable glucose control and significantly less hypoglycemia than sensor-augmented pump (SAP) therapy, according to a study published online March 13 in Diabetes Care.

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Guidelines Updated for Evaluating, Treating Hirsutism

THURSDAY, March 15, 2018 (HealthDay News) -- As an update to an earlier clinical practice guideline, recommendations for evaluating and treating hirsutism in premenopausal women have been issued and published online March 7 in the Journal of Clinical Endocrinology & Metabolism.

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Higher Exposure to Air Pollution Adds to CVD Risk for Blacks

THURSDAY, March 15, 2018 (HealthDay News) -- Blacks have significantly higher exposure to ambient fine particulate matter (particles with median aerodynamic diameter <2.5 µm [PM2.5]), with exposure associated with elevated blood glucose, worse endothelial function, and incident cardiovascular disease (CVD), according to a study published online March 15 in Arteriosclerosis, Thrombosis, and Vascular Biology.

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Grilled Meat, Chicken Ups Risk of Type 2 Diabetes in U.S. Adults

THURSDAY, March 15, 2018 (HealthDay News) -- Open-flame and/or high-temperature cooking methods (such as grilling/barbecuing, broiling, or roasting) to prepare chicken and red meat are associated with an increased risk of type 2 diabetes (T2D), according to a study published online March 12 in Diabetes Care.

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Drug Copayments Often Exceed Prescription Drug Costs

WEDNESDAY, March 14, 2018 (HealthDay News) -- Drug copayments frequently exceed prescription drug costs, with overpayments affecting 23 percent of all prescriptions, according to a research letter published in the March 13 issue of the Journal of the American Medical Association.

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Improved Glycemic Control With Surgical Tx of Obesity in Teens

WEDNESDAY, March 14, 2018 (HealthDay News) -- Surgical treatment of severe obesity in adolescents with type 2 diabetes is associated with better glycemic control and weight reduction than medical therapy, according to a study published online March 12 in JAMA Pediatrics.

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U.S. Spends Twice As Much for Similar Health Care Utilization

TUESDAY, March 13, 2018 (HealthDay News) -- Spending on health care is much higher in the United States than other high-income countries, but utilization rates are similar, according to a study published in the March 13 issue of the Journal of the American Medical Association.

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Great Recession Linked to Increase in BP, Blood Glucose

TUESDAY, March 13, 2018 (HealthDay News) -- The 2008 to 2010 Great Recession (GR) had a negative impact on the health of U.S. adults, with significant elevations in blood pressure and fasting glucose, according to a study published online March 12 in the Proceedings of the National Academy of Sciences.

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Three-Pronged Approach Can Improve Physician Engagement

MONDAY, March 12, 2018 (HealthDay News) -- The three-pronged approach implemented by one practice successfully improved physician engagement, according to an article published in Medical Economics.

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No Safety Concerns Noted in Study of Intranasal Insulin Use

MONDAY, March 12, 2018 (HealthDay News) -- Intranasal insulin application appears to be safe, according to a review published online March 6 in Diabetes, Obesity and Metabolism.

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Doctors Facing Challenge to Help Needy While Protecting Practices

FRIDAY, March 9, 2018 (HealthDay News) -- Physicians are increasingly being challenged to protect their practice finances while helping patients without insurance, according to an article published in Medical Economics.

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Circulating FGF23 Linked to Incident Coronary Heart Disease

FRIDAY, March 9, 2018 (HealthDay News) -- Higher circulating fibroblast growth factor 23 (FGF23) concentrations are associated with an increased risk of incident coronary heart disease (CHD), according to a study published online March 7 in JAMA Cardiology.

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Progression of Obesity Influences Risk of Diabetes Over Life Course

THURSDAY, March 8, 2018 (HealthDay News) -- Changes in weight influence the risk of diabetes, with lower risk of diabetes for obese individuals who lose weight versus stable obesity, according to a study published online March 5 in Diabetes Care.

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Few U.S. Adults Meet Most T2DM Risk Reduction Goals

WEDNESDAY, March 7, 2018 (HealthDay News) -- A small proportion of U.S. adults engage in lifestyle behaviors known to reduce the risk of type 2 diabetes, according to a study published in the March issue of Diabetes Care.

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Repeated Ranibizumab Doesn't Impair Macular Perfusion

WEDNESDAY, March 7, 2018 (HealthDay News) -- For patients with diabetic macular edema, repeated ranibizumab treatment does not appear to be associated with impaired macular perfusion, according to a study published online March 1 in JAMA Ophthalmology.

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Minorities Face Worse Prognosis and Complications in T1DM

TUESDAY, March 6, 2018 (HealthDay News) -- Compared to whites, blacks and Hispanics have increased markers of poor prognosis of type 1 diabetes at diagnosis and three years afterward, according to a study published online March 1 in Diabetes Care.

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ACP Updates Guidance for HbA1c Targets for Adults With T2DM

MONDAY, March 5, 2018 (HealthDay News) -- Guidance has been developed for hemoglobin A1c (HbA1c) targets for glycemic control among nonpregnant adults with type 2 diabetes; the guidance statement was published online March 6 in the Annals of Internal Medicine.

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Increase in Other Flavored Tobacco Use After Menthol Ban

MONDAY, March 5, 2018 (HealthDay News) -- Implementation of a ban on menthol cigarettes results in an increase in those attempting to quit, and an increase in use of other flavored tobacco or electronic-cigarette use, according to a study published online March 5 in JAMA Internal Medicine.

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Global Costs of Diabetes Will Continue Rising Through 2030

MONDAY, March 5, 2018 (HealthDay News) -- The global costs of diabetes are high and will increase substantially by 2030, according to a study published online Feb. 23 in Diabetes Care.

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Researchers ID Five Distinct Adult-Onset Diabetes Subgroups

FRIDAY, March 2, 2018 (HealthDay News) -- Reclassification of diabetes into subgroups shows differing courses of disease progression and risk of diabetic complications, according to a study published online March 1 in The Lancet Diabetes & Endocrinology.

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Leptin Tied to Sleep Quality in Obese Patients With T2DM

FRIDAY, March 2, 2018 (HealthDay News) -- Plasma leptin levels are independently associated with sleep quality in obese patients with type 2 diabetes, but not in those who are not obese, according to a study published online Feb. 26 in the Journal of Diabetes Investigation.

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Coverage Increased After ACA for Patients With Diabetes

THURSDAY, March 1, 2018 (HealthDay News) -- For adults aged 18 to 64 years with diabetes, there was an increase in health insurance coverage after implementation of the Affordable Care Act (ACA), according to a study published online Feb. 23 in Diabetes Care.

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Obesity Linked to Increased CVD Morbidity and Mortality

THURSDAY, March 1, 2018 (HealthDay News) -- Compared with normal body mass index (BMI), obesity is associated with increased morbidity and mortality linked to cardiovascular disease, and shorter longevity, according to a study published online Feb. 28 in JAMA Cardiology.

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Diet-Treated Chronic Illness May Lead to Disordered Eating

THURSDAY, March 1, 2018 (HealthDay News) -- Interventions for diet-treated chronic illnesses may increase the risk for disordered eating in children, according to a review published online Feb. 22 in the International Journal of Eating Disorders.

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Retinopathy Associated With Accelerated Cognitive Decline

THURSDAY, March 1, 2018 (HealthDay News) -- Retinopathy is associated with accelerated rates of 20-year cognitive decline, according to a study published online Feb. 28 in Neurology.

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Exposure to Metformin In Utero Ups Risk of Being Overweight

THURSDAY, March 1, 2018 (HealthDay News) -- Children exposed to metformin in utero have an increased risk of being overweight at age 4 years, according to research published online Feb. 27 in the Journal of Clinical Endocrinology and Metabolism.

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