Many Untreated CIN2 Lesions Regress Spontaneously

Share this content:
Many Untreated CIN2 Lesions Regress Spontaneously
Many Untreated CIN2 Lesions Regress Spontaneously

WEDNESDAY, Feb. 28, 2018 (HealthDay News) -- Most untreated cervical intraepithelial neoplasia grade 2 (CIN2) lesions regress, especially among women younger than 30 years, according to a review published online Feb. 27 in The BMJ.

Karoliina Tainio, M.D., from the University of Helsinki in Finland, and colleagues conducted a systematic review and meta-analysis to estimate the regression, persistence, and progression of untreated CIN2 lesions managed conservatively. Data were included from 36 studies with 3,160 women.

The researchers found that the pooled rates were 50 percent for regression, 32 percent for persistence, and 18 percent for progression at 24 months. The rates were 60, 23, and 11 percent, respectively, in a subgroup analysis of 1,069 women aged younger than 30 years. In prospective studies, the rate of non-compliance was about 10 percent.

"Most CIN2 lesions, particularly in young women (<30 years) regress spontaneously," the authors write. "Active surveillance, rather than immediate intervention, is therefore justified, especially among young women who are likely to adhere to monitoring."

Abstract/Full Text
Editorial

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: Progress in HIV Prevention Has Stalled in the United States

CDC: Progress in HIV Prevention Has Stalled in ...

Agency says effective HIV prevention, treatment not reaching those who could most benefit

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in Children

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in ...

All children with sustained unresponsiveness ingested concentrated and baked egg

Prenatal Vitamin Intake in Early Pregnancy May Cut Autism Risk

Prenatal Vitamin Intake in Early Pregnancy May Cut ...

ASD risk down for children whose mothers took prenatal vitamins during first month of pregnancy

is free, fast, and customized just for you!




Already a member?

Sign In Now »