Malnutrition Is Associated With Poor Prognosis in Heart Failure

Share this content:
Malnutrition Is Associated With Poor Prognosis in Heart Failure
Malnutrition Is Associated With Poor Prognosis in Heart Failure

FRIDAY, May 11, 2018 (HealthDay News) -- Patients with heart failure frequently have malnutrition, which is associated with increased mortality, according to a study published online May 9 in JACC: Heart Failure.

Shirley Sze, M.B.B.S., from Hull York Medical School in the United Kingdom, and colleagues applied the geriatric nutritional risk index (GNRI), controlling nutritional status (CONUT) score, and prognostic nutritional index (PNI) to 550,000 patients referred with suspected heart failure to examine the prognostic consequences of malnutrition.

The researchers confirmed heart failure in 3,386 of 4,021 patients enrolled. Overall, 6.7, 10.0, and 7.5 percent of patients were moderately or severely malnourished using scores for GNRI ≤91, CONUT >4, and PNI ≤38, respectively; 57 percent of participants were at least mildly malnourished by one or more scores. Overall, 51 percent of patients died during a median follow-up of 1,573 days. One-year mortality was 28, 41, and 36 percent for patients moderately or severely malnourished for CONUT, GNRI, and PNI, respectively, compared with 9 percent for those with mild malnutrition or normal nutritional status. One-year survival was predicted by a model including age, urea, and log-N-terminal pro-B-type natriuretic peptide (C-statistic, 0.719); additional of nutritional indices, but not body mass index, slightly improved prediction (C-statistic, up to 0.724).

"Malnutrition is common among outpatients with heart failure and is strongly related to increased mortality," the authors write.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Vit D Independently, Inversely Tied to Cholesterol in Children

Vit D Independently, Inversely Tied to Cholesterol in ...

Gene variants do not modify the associations of 25(OH)D with lipids

Ibalizumab Active in Multidrug Resistant HIV-1 Infection

Ibalizumab Active in Multidrug Resistant HIV-1 Infection

Lower degree of susceptibility to ibalizumab for nine of 10 patients with virology failure, rebound

Weight Gain After Quitting Smoking May Up T2DM Risk

Weight Gain After Quitting Smoking May Up T2DM ...

But temporary increase in type 2 diabetes risk does not attenuate benefits on total, CVD mortality

is free, fast, and customized just for you!




Already a member?

Sign In Now »