Majority of Fibromyalgia Drug Trials Are Industry Sponsored

This article originally appeared here.
Share this content:
Majority of Fibromyalgia Drug Trials Are Industry Sponsored
Majority of Fibromyalgia Drug Trials Are Industry Sponsored

(HealthDay News) -- Most fibromyalgia drug therapy randomized controlled trials (FM-RCTs) are funded by industry, and many authors have financial conflicts of interest (FCOIs), according to a study published online May 27 in the International Journal of Rheumatic Diseases.

Winnie K. Pang, M.D., from the University of Southern California-Los Angeles County Medical Center, and colleagues conducted a cross-sectional study of original, parallel-group, drug therapy FM-RCTs to examine the correlation between FCOIs and characteristics, outcomes, and reported methodological quality.

Data were included from 47 RCTs, with the funding source reported as industry (55.3 percent), non-profit (17 percent), mixed (10.6 percent), and unspecified (17 percent). The researchers found that RCTs funded by industry were more likely to be multicenter and enroll a greater number of patients. There was no difference in reporting between industry and non-profit funded RCTs; reporting of key methodological measures was found to be suboptimal. Almost two-thirds (63.8 percent) of RCTs had one or more authors who disclosed FCOIs. There was a univariate association for industry funding and certain authors' FCOIs with positive outcome; after adjustment for study sample size, the correlation did not persist.

"Continued surveillance of the potential influence of FCOIs on clinical trial outcomes, and policies to encourage transparent and adequate reporting of clinical trials will help to lessen concerns of industry bias in the study of drug therapies involving FM and other conditions," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Permits Marketing of Brain Stimulation Device for OCD

FDA Permits Marketing of Brain Stimulation Device for ...

FDA previously approved transcranial magnetic stimulation for major depression, certain migraines

Comments Open on End of NIH Review for Gene Therapy Studies

Comments Open on End of NIH Review for ...

NIH oversight panel no longer plans to review all applications for gene therapy experiments

U.S. Measles Outbreak Hits 107 Cases in 21 States, D.C.

U.S. Measles Outbreak Hits 107 Cases in 21 ...

Outbreak on track to exceed last year's; most of the people who got measles weren't vaccinated

is free, fast, and customized just for you!




Already a member?

Sign In Now »