Liver Proton Density Fat Fraction Drops After Bariatric Surgery

Share this content:
Liver Proton Density Fat Fraction Drops After Bariatric Surgery
Liver Proton Density Fat Fraction Drops After Bariatric Surgery

TUESDAY, Dec. 18, 2018 (HealthDay News) -- The average liver proton density fat fraction (PDFF) normalizes by a mean of 22.5 weeks after bariatric surgery, according to a study published online Dec. 18 in Radiology.

B. Dustin Pooler, M.D., from the University of Wisconsin School of Medicine and Public Health in Madison, and colleagues monitored liver fat before and after bariatric surgery using quantitative chemical shift-encoded (CSE) magnetic resonance imaging (MRI) in a prospective study. The authors recruited 126 participants with obesity who were undergoing evaluation for bariatric surgery and following a very low calorie diet (VLCD) preoperatively. Participants underwent CSE MRI measuring of liver PDFF before and after VLCD (two to three weeks and one to three days before surgery, respectively) and at one, three, and six to 10 months after surgery.

Fifty participants completed the study. The researchers found that the mean PDFF decreased to 4.9 ± 3.4 percent and mean body mass index decreased to 34.5 ± 5.4 kg/m² by six to 10 months after surgery. The mean estimated time was 22.5 ± 11.5 weeks for PDFF normalization. The only strong predictor for both change in PDFF and time to PDFF normalization was initial PDFF.

"There's no reason this clinical tool can't be used to monitor all sorts of weight loss patients," Pooler said in a statement. "We want patients and physicians to know that this is an option for them."

Several authors disclosed financial ties to the pharmaceutical and medical device industries.

Abstract/Full Text

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: Progress in HIV Prevention Has Stalled in the United States

CDC: Progress in HIV Prevention Has Stalled in ...

Agency says effective HIV prevention, treatment not reaching those who could most benefit

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in Children

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in ...

All children with sustained unresponsiveness ingested concentrated and baked egg

Prenatal Vitamin Intake in Early Pregnancy May Cut Autism Risk

Prenatal Vitamin Intake in Early Pregnancy May Cut ...

ASD risk down for children whose mothers took prenatal vitamins during first month of pregnancy

is free, fast, and customized just for you!




Already a member?

Sign In Now »