Liver Proton Density Fat Fraction Drops After Bariatric Surgery

Share this content:
Liver Proton Density Fat Fraction Drops After Bariatric Surgery
Liver Proton Density Fat Fraction Drops After Bariatric Surgery

TUESDAY, Dec. 18, 2018 (HealthDay News) -- The average liver proton density fat fraction (PDFF) normalizes by a mean of 22.5 weeks after bariatric surgery, according to a study published online Dec. 18 in Radiology.

B. Dustin Pooler, M.D., from the University of Wisconsin School of Medicine and Public Health in Madison, and colleagues monitored liver fat before and after bariatric surgery using quantitative chemical shift-encoded (CSE) magnetic resonance imaging (MRI) in a prospective study. The authors recruited 126 participants with obesity who were undergoing evaluation for bariatric surgery and following a very low calorie diet (VLCD) preoperatively. Participants underwent CSE MRI measuring of liver PDFF before and after VLCD (two to three weeks and one to three days before surgery, respectively) and at one, three, and six to 10 months after surgery.

Fifty participants completed the study. The researchers found that the mean PDFF decreased to 4.9 ± 3.4 percent and mean body mass index decreased to 34.5 ± 5.4 kg/m² by six to 10 months after surgery. The mean estimated time was 22.5 ± 11.5 weeks for PDFF normalization. The only strong predictor for both change in PDFF and time to PDFF normalization was initial PDFF.

"There's no reason this clinical tool can't be used to monitor all sorts of weight loss patients," Pooler said in a statement. "We want patients and physicians to know that this is an option for them."

Several authors disclosed financial ties to the pharmaceutical and medical device industries.

Abstract/Full Text

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Wait Times Have Improved in VA Health Care System

Wait Times Have Improved in VA Health Care ...

Wait times similar to private sector in 2014 but shorter overall and in some specialties in 2017

Medication Treatment for Substance Abuse Up in Facilities

Medication Treatment for Substance Abuse Up in Facilities

2007 to 2016 saw increase in use of medication treatment, reaching 36.1 percent in 2016

Mindfulness, Stress Linked to Menopausal Symptoms

Mindfulness, Stress Linked to Menopausal Symptoms

Link between mindfulness and symptoms more robust in women experiencing higher stress

is free, fast, and customized just for you!




Already a member?

Sign In Now »