Life Expectancy Equal to General Population With SVR in HCV

Share this content:
Life Expectancy Equal to General Population With SVR in HCV
Life Expectancy Equal to General Population With SVR in HCV

(HealthDay News) -- For patients with chronic hepatitis C virus (HCV) and bridging fibrosis or cirrhosis, attaining sustained virological response (SVR) is associated with life expectancy comparable to the general population, according to a study published in the Nov. 12 issue of the Journal of the American Medical Association.

Adriaan J. van der Meer, M.D., Ph.D., from the Erasmus MC University Medical Center Rotterdam in the Netherlands, and colleagues examined overall survival in patients with chronic HCV infection and bridging fibrosis or cirrhosis. Data were collected for 454 patients who were followed for a median of 8.4 years.

Of the participants, 36 percent attained SVR. The researchers found that 13 patients with SVR died, resulting in a cumulative 10-year overall survival rate of 91.1 percent, which was comparable to that of the age- and sex-matched general population (P = 0.57). One hundred patients without SVR died, resulting in a cumulative 10-year overall survival rate of 74.0 percent, which was significantly lower than the matched general population (P < 0.001).

"Among patients with chronic HCV infection and bridging fibrosis or cirrhosis, attaining SVR was associated with survival comparable with that of the general population, whereas not attaining SVR was associated with reduced survival," the authors write.

Several authors disclosed financial ties to the pharmaceutical and medical device industries.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Permits Marketing of Brain Stimulation Device for OCD

FDA Permits Marketing of Brain Stimulation Device for ...

FDA previously approved transcranial magnetic stimulation for major depression, certain migraines

Comments Open on End of NIH Review for Gene Therapy Studies

Comments Open on End of NIH Review for ...

NIH oversight panel no longer plans to review all applications for gene therapy experiments

U.S. Measles Outbreak Hits 107 Cases in 21 States, D.C.

U.S. Measles Outbreak Hits 107 Cases in 21 ...

Outbreak on track to exceed last year's; most of the people who got measles weren't vaccinated

is free, fast, and customized just for you!




Already a member?

Sign In Now »