Lasting Outcome Similar for ULS, SSLF for Pelvic Organ Prolapse

Share this content:
Lasting Outcome Similar for ULS, SSLF for Pelvic Organ Prolapse
Lasting Outcome Similar for ULS, SSLF for Pelvic Organ Prolapse

TUESDAY, April 17, 2018 (HealthDay News) -- For women with pelvic organ prolapse, there is no significant difference in five-year outcomes with uterosacral ligament suspension (ULS) and sacrospinous ligament fixation (SSLF) surgeries, and no difference in the success of perioperative behavioral therapy and pelvic floor muscle training (BPMT) or usual care, according to a study published in the April 17 issue of the Journal of the American Medical Association.

J. Eric Jelovsek, M.D., from the Cleveland Clinic, and colleagues conducted a 2 × 2 factorial randomized clinical trial at nine U.S. medical centers. Women were randomized to BPMT or usual care (186 and 188 women, respectively), or to surgical interventions: ULS or SSLF (188 and 186 women, respectively).

The researchers found that the estimated surgical failure rate was 61.5 and 70.3 percent in the ULS and SSLF groups, respectively (adjusted difference, −8.8 percent; 95 percent confidence interval, −24.2 to 6.6), by year five. The estimated anatomic failure rate was 45.6 and 47.2 percent in the BPMT and usual care groups, respectively (adjusted difference, −1.6 percent; 95 percent confidence interval, −21.2 to 17.9). Improvements in the Pelvic Organ Prolapse Distress Inventory scores were −59.4 and −61.8 in the BPMT and usual care groups, respectively (adjusted mean difference, 2.4; 95 percent confidence interval, −13.7 to 18.4).

"Compared with outcomes at two years, rates of surgical failure increased during the follow-up period, although prolapse symptom scores remained improved," the authors write.

Several authors disclosed financial relationships with UpToDate.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: Progress in HIV Prevention Has Stalled in the United States

CDC: Progress in HIV Prevention Has Stalled in ...

Agency says effective HIV prevention, treatment not reaching those who could most benefit

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in Children

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in ...

All children with sustained unresponsiveness ingested concentrated and baked egg

Prenatal Vitamin Intake in Early Pregnancy May Cut Autism Risk

Prenatal Vitamin Intake in Early Pregnancy May Cut ...

ASD risk down for children whose mothers took prenatal vitamins during first month of pregnancy

is free, fast, and customized just for you!




Already a member?

Sign In Now »