January 2019 Briefing - Nephrology

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Here are what the editors at HealthDay consider to be the most important developments in Nephrology for January 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Fruit, Vegetable Intake Very Low in Hemodialysis Population

THURSDAY, Jan. 31, 2019 (HealthDay News) -- Fruit and vegetable intake is very low in the hemodialysis population, with higher consumption associated with lower mortality, according to a study published online Jan. 31 in the Clinical Journal of the American Society of Nephrology.

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Benefits, Barriers to Exercise Examined for Patients With ESKD

TUESDAY, Jan. 29, 2019 (HealthDay News) -- Patients with end-stage kidney disease (ESKD) undergoing maintenance dialysis express a desire to exercise to regain energy and strength, but many report barriers to exercise, according to a study published online Jan. 29 in the Clinical Journal of the American Society of Nephrology.

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Report IDs Areas Lacking Good Practice in Health Tech Assessment

FRIDAY, Jan. 25, 2019 (HealthDay News) -- In a report published in the January issue of Value in Health, an ISPOR--The Professional Society for Health Economics and Outcomes Research working group indicates the lack of good practices in three areas of health technology assessment (HTA).

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Cognitive Scores After Kidney Transplant Tied to Frailty

FRIDAY, Jan. 25, 2019 (HealthDay News) -- Frail kidney transplant recipients have lower cognitive scores than nonfrail recipients four years after transplant, according to a study published online Jan. 24 in the Journal of the American Society of Nephrology.

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Flu-Like Illness Tied to Increased Relative Mortality in ESRD

THURSDAY, Jan. 24, 2019 (HealthDay News) -- Community activity for influenza-like illness (ILI) is associated with seasonal variation in all-cause mortality among patients with end-stage renal disease (ESRD), according to a study published online Jan. 24 in the Journal of the American Society of Nephrology.

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CDC: Proportion of Increased-Risk Deceased Organ Donors on Rise

THURSDAY, Jan. 24, 2019 (HealthDay News) -- Among deceased organ donors, there has been an increase in the proportion at increased risk for transmitting hepatitis B virus (HBV), hepatitis C virus (HCV), and HIV to recipients, according to research published in the Jan. 25 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Renal Transplant Improves Survival in ESRD Due to Lupus

WEDNESDAY, Jan. 23, 2019 (HealthDay News) -- For patients with end-stage renal disease (ESRD) due to lupus nephritis (LN), renal transplant is associated with a survival benefit, according to a study published online Jan. 22 in the Annals of Internal Medicine.

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Exome Sequencing Beneficial for Pediatric Kidney Recipients

TUESDAY, Jan. 22, 2019 (HealthDay News) -- Whole-exome sequencing (WES) can identify a genetic cause for almost one-third of pediatric kidney transplant recipients, according to a study published online Jan. 17 in the Journal of the American Society of Nephrology.

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Radiographic Knee Osteoarthritis Tied to Increased Risk for Death

FRIDAY, Jan. 18, 2019 (HealthDay News) -- Radiographic knee osteoarthritis (RKOA) is associated with an increased risk for mortality from cardiovascular disease (CVD), diabetes, and renal diseases, but self-reported OA is not, according to a study published in the December issue of the International Journal of Epidemiology.

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FDA Down to 5 Weeks of Funding to Review New Drug Applications

THURSDAY, Jan. 17, 2019 (HealthDay News) -- Due to the federal government shutdown, the U.S. Food and Drug Administration has only about five weeks of funding left to review new drug applications, according to Commissioner Scott Gottlieb, M.D.

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Adoption of Advanced Health IT Capabilities Inconsistent

WEDNESDAY, Jan. 16, 2019 (HealthDay News) -- Adoption of advanced health information technology (HIT) capabilities is inconsistent across health care systems, with electronic health record (EHR) standardization being the strongest predictor of advanced capabilities, according to a study published in the January issue of the American Journal of Managed Care.

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Personalized Tx May Extend Life in CKD With Small Renal Tumors

WEDNESDAY, Jan. 16, 2019 (HealthDay News) -- Personalized treatment selection may extend life expectancy in patients with chronic kidney disease (CKD) and small renal tumors (≤4 cm), according to a study published online Jan. 15 in Radiology.

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Study Explores Influence of Genetics, Environment in Disease

TUESDAY, Jan. 15, 2019 (HealthDay News) -- The influence of heritability and environmental factors has been identified for a large number of phenotypes, according to a study published online Jan. 14 in Nature Genetics.

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American College of Physicians Releases 7th Edition of Ethics Manual

TUESDAY, Jan. 15, 2019 (HealthDay News) -- Ethical principles are discussed in an updated Ethics Manual, issued by the American College of Physicians (ACP) and published as a supplement to the Jan. 15 issue of the Annals of Internal Medicine.

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Prices Still Explain High U.S. Health Care Spending

FRIDAY, Jan. 11, 2019 (HealthDay News) -- The difference in health spending between the United States and other countries is still explained by health care prices, according to a study published in the January issue of Health Affairs.

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Private Equity Acquisition of Physician Practices Discussed

THURSDAY, Jan. 10, 2019 (HealthDay News) -- The phenomenon of private equity acquisition of physician practices is discussed in an Ideas and Opinions piece published online Jan. 8 in the Annals of Internal Medicine.

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Many Female Health Care Workers Live in Poverty

WEDNESDAY, Jan. 9, 2019 (HealthDay News) -- Many U.S. female health care workers, particularly women of color, live in poverty and lack health insurance, according to a study published online Dec. 20 in the American Journal of Public Health.

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Increase in Brand-Name Drug Cost Mainly Due to Existing Drugs

WEDNESDAY, Jan. 9, 2019 (HealthDay News) -- The costs of oral and injectable brand-name drugs increased from 2008 to 2016, with most of the increase due to existing drugs, while new drugs accounted for cost increases in specialty and generic drugs, according to a study published in the January issue of Health Affairs.

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Medical Marketing Has Increased in Past 20 Years

TUESDAY, Jan. 8, 2019 (HealthDay News) -- From 1997 through 2016, there was an increase in medical marketing, especially direct-to-consumer (DTC) advertising, according to research published in the Jan. 1/8 issue of the Journal of the American Medical Association.

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Costs Higher for Those With Comorbid Noncommunicable Diseases

TUESDAY, Jan. 8, 2019 (HealthDay News) -- The costs of having two noncommunicable diseases (NCDs) is generally superadditive, according to a study published online Jan. 8 in PLOS Medicine.

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Cancer Death Rate in U.S. Decreased Continuously From 1991 to 2016

TUESDAY, Jan. 8, 2019 (HealthDay News) -- The overall cancer death rate decreased continuously by 27 percent from 1991 to 2016, according to a report published online Jan. 8 in CA: A Cancer Journal for Clinicians.

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ACA Coverage Gains Could Erode Without Individual Mandate

TUESDAY, Jan. 8, 2019 (HealthDay News) -- Eliminating the Affordable Care Act's individual mandate penalty is unlikely to destabilize the individual market in California but could roll back coverage gains, according to a study published in the January issue of Health Affairs.

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Multimethod Approach Improves ID of Med Nonadherence

MONDAY, Jan. 7, 2019 (HealthDay News) -- An approach involving a combination of provider report and pharmacy refill data can improve identification of medication nonadherence among youth with chronic kidney disease (CKD), according to a study published in the January issue of Pediatric Nephrology.

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Health Benefits of Nonsugar Sweeteners Uncertain

FRIDAY, Jan. 4, 2019 (HealthDay News) -- There is no compelling evidence to indicate health benefits of nonsugar sweetener (NSS) use on a range of health outcomes, according to a review published online Jan. 2 in The BMJ.

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Kidney Stones Tied to Increased Renal Cell Carcinoma Risk

WEDNESDAY, Jan. 2, 2019 (HealthDay News) -- Kidney stones are associated with an increased risk for renal cell carcinoma (RCC), specifically papillary RCC, and upper tract urothelial carcinoma (UTUC), according to a study published online Dec. 19 in the British Journal of Cancer.

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